Hu CD41b Pure HIP2 100ug
货号:
555468 基本售价:
3150.0 元 规格:
100ug
产品信息
概述货号 | 555468 |
描述 | The HIP2 monoclonal antibody specifically binds to CD41b. CD41b/CD41 is encoded by the ITGA2B gene and is also known as Platelet glycoprotein GPIIb and Integrin alpha IIb. CD41 is transmembrane glycoprotein that is post-translationally processed into a disulfide linked α-chain and β-chain. CD41 combines with CD61, otherwise known as Glycoprotein IIIa or β3 integrin, to form the CD41/CD61 (GPIIb/IIIa) complex. This complex is expressed on platelets and megakaryocytes and is involved in platelet activation, aggregation and binding to extracellular matrix proteins. Upon platelet activation, the CD41/CD61 complex can function as a receptor for fribrinogen, fibronectin and von Willebrand factor. In contrast to other CD41b antibodies, HIP2 does not detect anti-ZWa bound to GPIIb/IIIa. This antibody appears to be a weak aggregation inducer. |
别名 | ITGA2B; CD41; GP2B; GPIIb; GPalpha IIb; Platelet glycoprotein GPIIb |
同种亚型 | IgG3,κ |
反应种属 | Human (QC Testing) |
来源宿主 | Mouse |
使用方法 | FC |
性能供应商 | BD Pharmingen |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
|
存储溶液 | Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. |
浓度 | 0.5 mg/ml |