Hu Neuropilin-1 BV421 U21-1283 100Tst
货号：
565953 基本售价：
3080.0 元 规格：
100Tst
产品信息
概述| 货号 | 565953 |
| 描述 | The U21-1283 monoclonal antibody specifically recognizes Neuropilin-1 (NRP1) which is also known as CD304, Blood dendritic cell antigen 4 (BDCA4), or Vascular endothelial cell growth factor 165 receptor (VEGF165R). CD304 is a type I transmembrane glycoprotein that is involved in the development of the nervous and cardiovascular systems. It mediates the interaction, growth, survival, and migration of a variety of normal or tumor cells. CD304 is expressed on neurons, thymocytes, regulatory T cells, a subset of T follicular helper cells, dendritic cells, endothelial cells, and certain tumor cells. Neuropilin-1 has a very short cytoplasmic domain and interacts with various coreceptors to form ligand-binding, signal-transducing receptor complexes. CD304 complexes with Plexin-A family members to bind chemorepellent Class 3 Semaphorins and to guide neuronal axon growth. It also functions as a coreceptor with VEGFR2/CD309 to stimulate angiogenesis in response to VEGF165. CD304 serves to mediate the interactions between some T cells and dendritic cells. |
| 别名 | Neuropilin; NRP; NP1; Blood dendritic cell antigen 4; BDCA-4; VEGF165R |
| 同种亚型 | Mouse IgG2b, κ |
| 反应种属 | Human (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Recombinant Human Neuropilin-1 |
| 标记 | BV421 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BV421 under optimum conditions, and unconjugated antibody and free BD Horizon™ BV421 were removed.
|
| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
