Hu/NHP IFN-Gma PE-Cy7 4S.B3 50Tst
货号：
560741 基本售价：
2960.0 元 规格：
50Tst
产品信息
概述| 货号 | 560741 |
| 描述 | The 4S.B3 monoclonal antibody specifically binds to interferon-γ (IFN-γ). The immunogen used to generate this hybridoma was partially purified human IFN-γ obtained from supernatants of human PBMC stimulated with Staphylococcus aureus. Interferon-γ (IFN-γ) is a potent multifunctional cytokine that is produced by several activated cell types including NK, NKT, CD4+TCRαβ+, CD8+TCRαβ+, and TCRγδ + T cells. IFN- γ exerts its biological effects through specific binding to the high-affinity IFN-γ Receptor Complex comprised of IFN-γRα (CD119) and IFN-γRβ subunits. In addition to its antiviral effects, IFN- γ upregulates a number of lymphoid cell functions including the antimicrobial and antitumor responses of macrophages, NK cells, and neutrophils. In addition, IFN- γ can exert strong regulatory influences on the proliferation, differentiation, and effector responses of B cell and T cell subsets. Th ese influences can involve IFN- γ ’s capacity to boost MHC class I and II expression by antigen-presenting cells as well as to direct effects on B cells and T cells themselves. Human IFN-γ is a 14- 18 kDa glycoprotein containing 143 amino acid residues. |
| 同种亚型 | IgG1,κ |
| 反应种属 | Rhesus, Cynomolgus, Baboon (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | IC/FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human IFN-γ from supernatants of S. aureus-stimulated PBMC |
| 标记 | PE-Cy7 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with PE-Cy7 under optimum conditions, and unconjugated antibody and free PE-Cy7 were removed.
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| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
