HU CD41A BB515 HIP8 25TST
货号：
565938 基本售价：
2850.0 元 规格：
25TST
产品信息
概述| 货号 | 565938 |
| 描述 | The HIP8 monoclonal antibody specifically binds to the α -chain of CD41. CD41 is also known as Integrin α IIb or Platelet GPIIb. The calcium-dependent complex of CD41 and CD61 ( β 3 integrin or GPIIIa) is normally expressed on platelets and megakaryocytes. The CD41/CD61 complex is the receptor for fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation. CD41 (clone HIP8) completely inhibits ADP-, epinephrine-, and collagen-induced platelet activation, and partially inhibits ristocetin- and thrombin-induced platelet activation. This antibody is useful in the morphological and physiological studies of platelets and megakaryocytes. |
| 别名 | ITGA2B; Integrin alpha-2b (αIIb); Platelet glycoprotein IIb (GPIIb) |
| 同种亚型 | Mouse BALB/c IgG1, κ |
| 反应种属 | Human (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Purified platelet membrane glycoproteins |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BB515 under optimum conditions and unconjugated antibody was removed.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
