Hu MIG (CXCL9) PE B8-11 50Tst
货号：
566013 基本售价：
2795.0 元 规格：
50Tst
产品信息
概述| 货号 | 566013 |
| 描述 | The B8-11 monoclonal antibody specifically recognizes monokine induced by gamma interferon (MIG), which is also known as chemokine (C-X-C motif) ligand 9 (CXCL9). MIG is a chemotactic cytokine that belongs to the CXC subfamily of chemokines. MIG is predominantly expressed by monocytes, macrophages, hepatocytes, and endothelial cells in response to interferon-gamma (IFN- γ ) stimulation. It is primarily involved in the recruitment of activated T cells. MIG/CXCL9, and the closely-related IP10/CXCL10 and I-TAC/CXCL11 chemokines, exert their biological activities by binding to and signaling through the CXCR3 (CD183) chemokine receptor. CXCR3 is expressed on multiple cell types but predominantly on memory and effector T cells. The CXCL9 and CXCR3 interaction plays an important role in the onset of inflammation and is implicated in the pathogenesis of T-cell mediated immunity in several disease models. |
| 别名 | C-X-C motif chemokine 9; CMK; crg-10; Humig; SCYB9 |
| 同种亚型 | Mouse IgG1, κ |
| 反应种属 | Human (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Recombinant Human MIG Protein |
| 标记 | PE |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
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| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
