Hu CD95 NHP BV421 DX2 50Tst
货号：
562648 基本售价：
2385.0 元 规格：
50Tst
产品信息
概述| 货号 | 562648 |
| 描述 | The DX2 monoclonal antibody specifically binds to the human Fas antigen (also called APO-1). This 45 kDa transmembrane cell surface molecule was designated as CD95 at the Fifth HLDA Workshop. Fas is a member of the TNF-receptor superfamily and is also known as Tumor necrosis factor receptor superfamily member 6 (TNFRSF6). It is expressed on a variety of normal and neoplastic cells including activated T and B lymphocytes and some undifferentiated thymocytes. The Fas/CD95 antigen is a polypeptide that plays a role in the programmed sequence of events leading to cell death, termed apoptosis. The DX2 clone specifically reacts with murine L cells, murine L1210 leukemia cells and murine P815 mastocytoma cells transfected with human Fas cDNA but not with untransfected parental cell lines. Crosslinking CD95 with DX2 antibody delivers an apoptotic signal indicating that DX2 recognizes a functional epitope of the CD95 antigen. |
| 别名 | APO-1; FAS; TNFRSF6; APT1; ALPS1A; FAS1; FASTM; FASLG receptor |
| 同种亚型 | Mouse C3H, also known as C3H/He, C3H/Bi IgG1< |
| 反应种属 | Rhesus, Cynomolgus, Baboon (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human CD95-transfected L Cells |
| 标记 | BV421 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BV421 under optimum conditions, and unconjugated antibody and free BD Horizon™ BV421 were removed.
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| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
