Hu CD158b Pure CH-L 100ug
货号：
559783 基本售价：
2016.0 元 规格：
100ug
产品信息
概述| 货号 | 559783 |
| 描述 | The CH-L monoclonal antibody specifically binds to CD158b proteins. These proteins are 50-58 kDa type I glycoproteins that belong to the killer cell inhibitory receptor (KIR) family. They are also known as CD158b1 (Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2/KIR2DL2; NKAT-6; p58.2); CD158b2 (Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3/KIR2DL3; NKAT-2; p58.2); or CD158j (Killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2/KIR2DS2; NKAT-5; p50.2). CD158b molecules are composed of two extracellular Ig-like domains, a transmembrane region, and either long (76-84 amino acids) or short (39 amino acid) cytoplasmic tails. They are expressed on NK cells and subsets of TCR αβ+ cells or TCR γδ+ cells. Ligand- or CH-L antibody-bound CD158b1 or CD158b2 can reportedly inhibit cytolytic NK and T cell responses to various stimuli including certain target cells expressing MHC class I ligands encoded by HLA-C alleles (Cw 1, 3, 7 and 8). CD158j reportedly may enhance some cellular cytolytic responses. |
| 同种亚型 | IgG2b,κ |
| 反应种属 | Human (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
