| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. 4-methylumbelliferone diminishes catabolically-activated articular chondrocytes and cartilage explants via a mechanism independent of hyaluronan inhibition
J Biol Chem, 2016;0(0):.
Species: Human
Sample Type: Cell Lysates
Impaired Synthesis of Stromal Components in Response to Minnelide Improves Vascular Function, Drug Delivery, and Survival in Pancreatic Cancer.
Authors: Banerjee S, Modi S, McGinn O, Zhao X, Dudeja V, Ramakrishnan S, Saluja A
Clin Cancer Res, 2016;22(2):415-25.
Species: Mouse
Sample Type: Tissue Homogenates
Hyaluronan Does Not Regulate Human Epidermal Keratinocyte Proliferation and Differentiation
Authors: J Malaisse, V Pendaries, F Hontoir, V De Glas, D Van Vlaend, M Simon, C Lambert de, Y Poumay, B Flamion
J. Biol. Chem, 2016;291(12):6347-58.
Species: Human
Sample Type: Cell Culture Supernates
Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis
J Clin Invest, 2016;0(0):.
Species: Human
Sample Type: Cell Culture Supernates
Chronic lymphocytic leukemia: a paradigm of innate immune cross-tolerance.
Authors: Jurado-Camino T, Cordoba R, Esteban-Burgos L, Hernandez-Jimenez E, Toledano V, Hernandez-Rivas J, Ruiz-Sainz E, Cobo T, Siliceo M, Perez de Diego R, Belda C, Cubillos-Zapata C, Lopez-Collazo E
J Immunol, 2015;194(2):719-27.
Species: Human
Sample Type: Serum
Articular Joint Lubricants during Osteoarthritis and Rheumatoid Arthritis Display Altered Levels and Molecular Species.
Authors: Kosinska M, Ludwig T, Liebisch G, Zhang R, Siebert H, Wilhelm J, Kaesser U, Dettmeyer R, Klein H, Ishaque B, Rickert M, Schmitz G, Schmidt T, Steinmeyer J
PLoS ONE, 2015;10(5):e0125192.
Species: Human
Sample Type: Synovial Fluid
Inhibition of hyaluronan synthesis protects against central nervous system (CNS) autoimmunity and increases CXCL12 expression in the inflamed CNS.
Authors: Mueller A, Yoon B, Sadiq S
J Biol Chem, 2014;289(33):22888-99.
Species: Human
Sample Type: cell supernates
Molecular mass dependence of hyaluronan detection by sandwich ELISA-like assay and membrane blotting using biotinylated hyaluronan binding protein.
Authors: Yuan, Han, Tank, Mihir, Alsofyani, Abeer, Shah, Naman, Talati, Nishant, LoBello, Jaclyn C, Kim, Jin Ryou, Oonuki, Yoji, de la Motte, Carol A, Cowman, Mary K
Glycobiology, 2013;23(11):1270-80.
Species: N/A
Sample Type: protein
Murine hyaluronidase 2 deficiency results in extracellular hyaluronan accumulation and severe cardiopulmonary dysfunction.
Authors: Chowdhury, Biswajit, Hemming, Richard, Hombach-Klonisch, Sabine, Flamion, Bruno, Triggs-Raine, Barbara
J Biol Chem, 2013;288(1):520-8.
Species: Mouse
Sample Type: Serum
Effective targeting of the tumor microenvironment for cancer therapy.
Authors: Jiang P, Li X, Thompson CB
Anticancer Res., 2012;32(4):1203-12.
Species: Human
Sample Type: Cell Culture Supernates
Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors.
Authors: Schledzewski K, Geraud C, Arnold B, Wang S, Grone HJ, Kempf T, Wollert KC, Straub BK, Schirmacher P, Demory A, Schonhaber H, Gratchev A, Dietz L, Thierse HJ, Kzhyshkowska J, Goerdt S
J. Clin. Invest., 2011;121(2):703-14.
Species: Mouse
Sample Type: Plasma
Peroxisome Proliferator-activated Receptor gamma Ligands Inhibit Transforming Growth Factor-beta-induced, Hyaluronan-dependent, T Cell Adhesion to Orbital Fibroblasts.
Authors: Guo N, Woeller CF, Feldon SE, Phipps RP
J. Biol. Chem., 2011;286(21):18856-67.
Species: Human
Sample Type: Cell Culture Supernates
Mast cell-derived prostaglandin D2 controls hyaluronan synthesis in human orbital fibroblasts via DP1 activation: implications for thyroid eye disease.
Authors: Guo N, Baglole CJ, OLoughlin CW, Feldon SE, Phipps RP
J. Biol. Chem., 2010;285(21):15794-804.
Species: Human
Sample Type: Cell Culture Supernates
Chronic cigarette smoke exposure generates pathogenic T cells capable of driving COPD-like disease in Rag2-/- mice.
Authors: Motz GT, Eppert BL, Wesselkamper SC, Flury JL, Borchers MT
Am. J. Respir. Crit. Care Med., 2010;181(11):1223-33.
Species: Mouse
Sample Type: BALF
CD44 deficiency is associated with increased bacterial clearance but enhanced lung inflammation during Gram-negative pneumonia.
Authors: van der Windt GJ, Florquin S, de Vos AF
Am. J. Pathol., 2010;177(5):2483-94.
Species: Mouse
Sample Type: BALF
Hyaluronan synthesis mediates the fibrotic response of keratocytes to transforming growth factor beta.
Authors: Guo N, Li X, Mann MM, Funderburgh ML, Du Y, Funderburgh JL
J. Biol. Chem., 2010;285(42):32012-9.
Species: Bovine
Sample Type: Cell Culture Supernates
Platelet-derived hyaluronidase 2 cleaves hyaluronan into fragments that trigger monocyte-mediated production of proinflammatory cytokines.
Authors: de la Motte C, Nigro J, Vasanji A, Rho H, Kessler S, Bandyopadhyay S, Danese S, Fiocchi C, Stern R
Am. J. Pathol., 2009;174(6):2254-64.
Species: Human
Sample Type: Cell Culture Supernates
Imatinib mesylate and AMN107 inhibit PDGF-signaling in orbital fibroblasts: a potential treatment for Graves' ophthalmopathy.
Authors: van Steensel L, Paridaens D, Schrijver B, Dingjan GM, van Daele PL, van Hagen PM, van den Bosch WA, Drexhage HA, Hooijkaas H, Dik WA
Invest. Ophthalmol. Vis. Sci., 2009;50(7):3091-8.
Species: Human
Sample Type: Cell Culture Supernates
High levels of hyaluronan in idiopathic pulmonary arterial hypertension.
Authors: Aytekin M, Comhair SA, de la Motte C, Bandyopadhyay SK, Farver CF, Hascall VC, Erzurum SC, Dweik RA
Am. J. Physiol. Lung Cell Mol. Physiol., 2008;295(5):L789-99.
Species: Human
Sample Type: Plasma
TGFbeta2-mediated production of hyaluronan is important for the induction of epicardial cell differentiation and invasion.
Authors: Craig EA, Craig E, Austin A, Austin AF, Vaillancourt RR, Vaillancourt R, Barnett JV, Camenisch T, Camenisch TD
Exp Cell Res, 0;316(20):3397-405.
Species: Mouse
Sample Type: Cell Culture Supernates
Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.
Authors: Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Schaefer R, Grone HJ, Schaefer L
J Biol Chem, 0;284(36):24035-48.
Species: Mouse
Sample Type: Cell Culture Supernates
4-Methylumbelliferone Diminishes Catabolically Activated Articular Chondrocytes and Cartilage Explants via a Mechanism Independent of Hyaluronan Inhibition.
Authors: Ishizuka S, Askew E, Ishizuka N, Knudson C, Knudson W
J Biol Chem, 0;291(23):12087-104.
Species: Human
Sample Type: Cell Culture Supernates
Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients.
Authors: Bellini A, Marini MA, Bianchetti L, Barczyk M, Schmidt M, Mattoli S
Mucosal Immunol, 0;5(2):140-9.
Species: Human
Sample Type: Cell Culture Supernates
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