Rat MAG/Siglec-4a DuoSet ELISA, 15 Plate (1 KT)
货号:
DY538 基本售价:
10120.7 元 规格:
1 KIT
产品信息
概述货号 | DY538 |
别名 | GMAsialic acid binding Ig-like lectin 4A; MAG; myelin associated glycoprotein; myelin-associated glycoprotein; sialic acid-binding immunoglobulin-like lectin 4A; Siglec4a; Siglec-4a; S-MAG |
全称 | Myelin-associated Glycoprotein | 反应种属 | Rat |
目标/特异性 | Please see the product datasheet |
性能供应商 | R&D Systems |
检测类型 | Solid Phase Sandwich ELISA |
Entrez Gene IDs | 4099 (Human); 17136 (Mouse); 29409 (Rat); |
背景 | MAG (Myelin-Associated Glycoprotein), also known as Siglec-4a, is a transmembrane lectin that preferentially binds to alpha-2,3-linked sialic acid terminal carbohydrates on cell surface molecules. It is expressed by myelinating oligodendrocytes and Schwann cells and plays an important role in axon-myelin stability. MAG also regulates axon structure at nodes of Ranvier, inhibits neurite outgrowth, and protects neurons from excitotoxicity. It interacts with the gangliosides GD1a and GT1b, the Nogo receptors NgR1 and NgR2/NgRH1, Integrin beta 1/CD29, and PIR-B. Proteolytic cleavage releases a soluble form that is released from myelin in large quantities. |
运输条件 | Blue Ice |
存放说明 | 4℃ |