| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Lung protective ventilation induces immunotolerance and nitric oxide metabolites in porcine experimental postoperative sepsis.
Authors: Sperber J, Lipcsey M, Larsson A, Larsson A, Sjolin J, Castegren M
PLoS ONE, 2013;8(12):e83182.
Species: Porcine
Sample Type: Plasma
Characterization of homologous and heterologous adaptive immune responses in porcine reproductive and respiratory syndrome virus infection.
Authors: Diaz I, Gimeno M, Darwich L, Navarro N, Kuzemtseva L, Lopez S, Galindo I, Segales J, Martin M, Pujols J, Mateu E
Vet. Res., 2012;43(1):30.
Species: Porcine
Sample Type: Serum
N(pro) of Classical Swine Fever Virus Prevents Type I Interferon-Mediated Priming of Conventional Dendritic Cells for Enhanced Interferon-alpha Response.
Authors: Husser L, Ruggli N, Summerfield A
J. Interferon Cytokine Res., 2012;32(5):221-9.
Species: Porcine
Sample Type: Cell Culture Supernates
Cytokine protein expression levels in tracheobronchial lymph node homogenates of pigs infected with pseudorabies virus.
Authors: Miller LC, Zanella EL, Waters WR
Clin. Vaccine Immunol., 2010;17(5):728-34.
Species: Porcine
Sample Type: Tissue Homogenates
Inflammatory and circulatory effects of the reduction of endotoxin concentration in established porcine endotoxemic shock--a model of endotoxin elimination.
Authors: Carlsson M, Lipcsey M, Larsson A, Tano E, Rubertsson S, Eriksson M, Sjolin J
Crit. Care Med., 2009;37(3):1031-e4.
Species: Porcine
Sample Type: Plasma
Impact of topical cooling solution and prediction of pulmonary graft viability from non-heart-beating donors.
Authors: Inci I, Arni S, Inci D, Zhai W, Hillinger S, Leskosek B, Vogt P, Weder W
J. Heart Lung Transplant., 2008;27(9):1016-22.
Species: Porcine
Sample Type: BALF
Early administration of probiotics alters bacterial colonization and limits diet-induced gut dysfunction and severity of necrotizing enterocolitis in preterm pigs.
Authors: Siggers RH, Siggers J, Boye M, Thymann T, Molbak L, Leser T, Jensen BB, Sangild PT
J. Nutr., 2008;138(8):1437-44.
Species: Porcine
Sample Type: Tissue Homogenates
Toll-like receptor 7 and MyD88 knockdown by lentivirus-mediated RNA interference to porcine dendritic cell subsets.
Authors: Alves MP, Neuhaus V, Guzylack-Piriou L, Ruggli N, McCullough KC, Summerfield A
Gene Ther., 2007;14(10):836-44.
Species: Porcine
Sample Type: Cell Culture Supernates
In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid.
Authors: Saurer L, McCullough KC, Summerfield A
J. Immunol., 2007;179(6):3504-14.
Species: Porcine
Sample Type: Cell Culture Supernates
Neutrophil and small intestinal lymphocyte migration after Salmonella typhimurium infection: impact of fermentable fiber.
Authors: Milo LA, Correa-Matos NJ, Donovan SM, Tappenden KA
J. Pediatr. Gastroenterol. Nutr., 2004;39(1):73-9.
Species: Porcine
Sample Type: Plasma
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| 背景 | IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. It contributes to chronic inflammation in obesity, insulin resistance, inflammatory bowel disease, arthritis, sepsis, and atherosclerosis. IL-6 signals through a receptor complex of IL-6 R alpha and gp130. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 R alpha are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 R alpha elicit responses from gp130-expressing cells that lack cell surface IL-6 R alpha. |
