Mouse CXCL12/SDF-1 DuoSet ELISA, 15 Plate (1 KT)【科瑞奥博】

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Mouse CXCL12/SDF-1 DuoSet ELISA, 15 Plate (1 KT)

货号： DY460 基本售价： 10120.7 元规格： 1 KIT

产品信息

概述
货号	DY460
别名	chemokine (C-X-C motif) ligand 12; C-X-C motif chemokine 12; CXCL12; hIRH; hSDF-1; Intercrine reduced in hepatomas; IRH; PBSF; PBSFSDF-1a; Pre-B cell growth-stimulating factor; SCYB12; SDF1; SDF-1; SDF1A; SDF1B; SDF1SDF-1b; stromal cell-derived factor 1; TLSF; TLSF-a; TLSF-b; TPAR1
反应种属	Mouse
目标/特异性	Please see the product datasheet

性能
供应商	R&D Systems
检测类型	Solid Phase Sandwich ELISA
Entrez Gene IDs	6387 (Human); 20315 (Mouse); 493806 (Feline); 574334 (Rhesus Macaque);
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment EMBO Mol Med, 2016;0(0):. Species: Mouse Sample Type: Cell Culture Supernates Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction. Authors: Projahn D, Simsekyilmaz S, Singh S, Kanzler I, Kramp B, Langer M, Burlacu A, Bernhagen J, Klee D, Zernecke A, Hackeng T, Groll J, Weber C, Liehn E, Koenen R J Cell Mol Med, 2014;18(5):790-800. Species: Mouse Sample Type: cell supernates Molecular changes in bone marrow, tumor and serum after conductive ablation of murine 4T1 breast carcinoma. Authors: Przybyla B, Shafirstein G, Vishal S, Dennis R, Griffin R Int J Oncol, 2014;44(2):600-8. Species: Mouse Sample Type: Homogenized Tissue CX3CR1 regulates the maintenance of KLRG1+ NK cells into the bone marrow by promoting their entry into circulation. Authors: Ponzetta A, Sciume G, Benigni G, Antonangeli F, Morrone S, Santoni A, Bernardini G J Immunol, 2013;191(11):5684-94. Species: Mouse Sample Type: cell culture supernate HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4. Authors: Schiraldi M, Raucci A, Munoz LM, Livoti E, Celona B, Venereau E, Apuzzo T, De Marchis F, Pedotti M, Bachi A, Thelen M, Varani L, Mellado M, Proudfoot A, Bianchi ME, Uguccioni M J. Exp. Med., 2012;209(3):551-63. Species: Mouse Sample Type: Cell Culture Supernates Chemokine binding protein M3 of murine gammaherpesvirus 68 modulates the host response to infection in a natural host. Authors: Hughes DJ, Kipar A, Leeming GH, Bennett E, Howarth D, Cummerson JA, Papoula-Pereira R, Flanagan BF, Sample JT, Stewart JP PLoS Pathog., 2011;7(3):e1001321. Species: Mouse Sample Type: Tissue Homogenates Dual effect of AMD3100, a CXCR4 antagonist, on bleomycin-induced lung inflammation. Authors: Watanabe M, Matsuyama W, Shirahama Y, Mitsuyama H, Oonakahara K, Noma S, Higashimoto I, Osame M, Arimura K J. Immunol., 2007;178(9):5888-98. Species: Mouse Sample Type: Tissue Homogenates Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing. Authors: Jung Y, Wang J, Schneider A, Sun YX, Koh-Paige AJ, Osman NI, McCauley LK, Taichman RS Bone, 2006;38(4):497-508. Species: Mouse Sample Type: Cell Culture Supernates
背景	CXCL12/Stromal Cell-derived Factor 1 (SDF-1) is a member of the CXC chemokine ligand superfamily. Six alternatively spliced CXCL12/SDF-1 isoforms have been identified including, CXCL12/SDF-1 alpha, CXCL12/SDF-1 beta, and CXCL12/SDF-1 gamma. CXCL12/SDF-1 alpha is 89 amino acids (aa) in length with a predicted molecular weight of 10 kDa, CXCL12/SDF-1 beta is 93 aa in length with a predicted molecular weight of 10.6 kDa, and CXCL12/SDF-1 gamma is 119 aa in length with a predicted molecular weight of 13.7 kDa. The mouse CXCL12/SDF-1 orthologs share 99% aa sequence identity with the human protein. The alpha and beta isoforms are ubiquitously expressed while the gamma isoform is primarily expressed in the heart. CXCL12/SDF-1 isoforms are chemotactic for T lymphocytes and monocytes. It is cardio protective and has also been shown to hinder CXCR4-mediated HIV infection of T cells.
运输条件	Blue Ice
存放说明	4℃