Contribution of the Ade Resistance-Nodulation-Cell Division-Type Efflux Pumps to Fitness and Pathogenesis of Acinetobacter baumannii
Authors: Eun-Jeong Yoon
MBio, 2016;7(3):.
Species: Mouse
Sample Type: BALF

Glucosylation drives the innate inflammatory response to Clostridium difficile Toxin A
Authors: Carrie A Cowardin
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Type: Cell Culture Supernates

Inducible Expression of CXCL1 within the Central Nervous System Amplifies Viral-Induced Demyelination.
Authors: Marro B, Grist J, Lane T
J Immunol, 2016;196(4):1855-64.
Species: Mouse
Sample Type: Cell Culture Supernates

C1P Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Preventing NF-?B Activation in Neutrophils
J Immunol, 2016;196(5):2319-26.
Species: Mouse
Sample Type: BALF

Poly-N-acetyl glucosamine production by Staphylococcus epidermidis cells increases their in vivo pro-inflammatory effect
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Type: Peritoneal Exudates

Inhibiting complex IL-17A and IL-17RA interactions with a linear peptide
Sci Rep, 2016;6(0):26071.
Species: Mouse
Sample Type: Cell Culture Supernates

Role of Complement C5 in Experimental Blunt Chest Trauma-Induced Septic Acute Lung Injury (ALI)
PLoS ONE, 2016;11(7):e0159417.
Species: Mouse
Sample Type: BALF

Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor
Sci Rep, 2016;6(0):26490.
Species: Mouse
Sample Type: Tissue Homogenates

Antiviral Activity of Oroxylin A against Coxsackievirus B3 Alleviates Virus-Induced Acute Pancreatic Damage in Mice
PLoS ONE, 2016;11(5):e0155784.
Species: Mouse
Sample Type: Serum

Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection.
Authors: Zhao Y, Olonisakin T, Xiong Z, Hulver M, Sayeed S, Yu M, Gregory A, Kochman E, Chen B, Mallampalli R, Sun M, Silverstein R, Stolz D, Shapiro S, Ray A, Ray P, Lee J
Mucosal Immunol, 2015;8(4):896-905.
Species: Mouse
Sample Type: Tissue Homogenates

Coadministration of Hedera helix L. Extract Enabled Mice to Overcome Insufficient Protection against Influenza A/PR/8 Virus Infection under Suboptimal Treatment with Oseltamivir.
Authors: Hong E, Song J, Shim A, Lee B, Kwon B, Song H, Kim Y, Chang S, Jeong H, Kim J, Seo S, Kim H, Kwon Y, Ko H
PLoS ONE, 2015;10(6):e0131089.
Species: Mouse
Sample Type: Tissue Homogenates

Smoking p66Shc knocked out mice develop respiratory bronchiolitis with fibrosis but not emphysema.
Authors: Lunghi B, De Cunto G, Cavarra E, Fineschi S, Bartalesi B, Lungarella G, Lucattelli M
PLoS ONE, 2015;10(3):e0119797.
Species: Mouse
Sample Type: BALF

Alveolar Epithelial A2B Adenosine Receptors in Pulmonary Protection during Acute Lung Injury.
Authors: Hoegl S, Brodsky K, Blackburn M, Karmouty-Quintana H, Zwissler B, Eltzschig H
J Immunol, 2015;195(4):1815-24.
Species: Mouse
Sample Type: BALF

Limited Contribution of IL-36 versus IL-1 and TNF Pathways in Host Response to Mycobacterial Infection.
Authors: Segueni N, Vigne S, Palmer G, Bourigault M, Olleros M, Vesin D, Garcia I, Ryffel B, Quesniaux V, Gabay C
PLoS ONE, 2015;10(5):e0126058.
Species: Mouse
Sample Type: Homogenized Tissue

Autoprocessing of neutrophil elastase near its active site reduces the efficiency of natural and synthetic elastase inhibitors.
Authors: Dau T, Sarker R, Yildirim A, Eickelberg O, Jenne D
Nat Commun, 2015;6(0):6722.
Species: Mouse
Sample Type: BALF

Poly(inosinic-cytidylic) acid-triggered exacerbation of experimental asthma depends on IL-17A produced by NK cells.
Authors: Lunding L, Webering S, Vock C, Behrends J, Wagner C, Holscher C, Fehrenbach H, Wegmann M
J Immunol, 2015;194(12):5615-25.
Species: Mouse
Sample Type: BALF

De novo-induced self-antigen-specific Foxp3+ regulatory T cells impair the accumulation of inflammatory dendritic cells in draining lymph nodes.
Authors: Alissafi T, Hatzioannou A, Ioannou M, Sparwasser T, Grun J, Grutzkau A, Verginis P
J Immunol, 2015;194(12):5812-24.
Species: Mouse
Sample Type: Cell Culture Supernates

Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NFkappaB Activity in Macrophages.
Authors: Hamers A, van Dam L, Teixeira Duarte J, Vos M, Marinkovic G, van Tiel C, Meijer S, van Stalborch A, Huveneers S, Te Velde A, de Jonge W, de Vries C
PLoS ONE, 2015;10(8):e0133598.
Species: Mouse
Sample Type: Cell Culture Supernates

Mast cells play an important role in chlamydia pneumoniae lung infection by facilitating immune cell recruitment into the airway.
Authors: Chiba N, Shimada K, Chen S, Jones H, Alsabeh R, Slepenkin A, Peterson E, Crother T, Arditi M
J Immunol, 2015;194(8):3840-51.
Species: Mouse
Sample Type: BALF

C1q Deficiency Promotes Pulmonary Vascular Inflammation and Enhances the Susceptibility of the Lung Endothelium to Injury.
Authors: Shah D, Romero F, Zhu Y, Duong M, Sun J, Walsh K, Summer R
J Biol Chem, 2015;290(49):29642-51.
Species: Mouse
Sample Type: BALF

The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection.
Authors: Schliehe C, Flynn E, Vilagos B, Richson U, Swaminathan S, Bosnjak B, Bauer L, Kandasamy R, Griesshammer I, Kosack L, Schmitz F, Litvak V, Sissons J, Lercher A, Bhattacharya A, Khamina K, Trivett A, Tessarollo L, Mesteri I, Hladik A, Merkler D, Kubicek S, Knapp S, Epstein M, Symer D, Aderem A, Bergthaler A
Nat Immunol, 2015;16(1):67-74.
Species: Mouse
Sample Type: BALF

C1q Modulates the Response to TLR7 Stimulation by Pristane-Primed Macrophages: Implications for Pristane-Induced Lupus.
Authors: Carlucci F, Ishaque A, Ling G, Szajna M, Sandison A, Donatien P, Cook H, Botto M
J Immunol, 2015;196(4):1488-94.
Species: Mouse
Sample Type: Serum

Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection.
Authors: Brown A, Murphy A, Lalor S, Leech J, OKeeffe K, Mac Aogain M, OHalloran D, Lacey K, Tavakol M, Hearnden C, Fitzgerald-Hughes D, Humphreys H, Fennell J, van Wamel W, Foster T, Geoghegan J, Lavelle E, Rogers T, McLoughlin R
PLoS Pathog, 2015;11(11):e1005226.
Species: Mouse
Sample Type: Cell Culture Supernates

Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.
Authors: Kearney C, Cullen S, Tynan G, Henry C, Clancy D, Lavelle E, Martin S
Cell Death Differ, 2015;22(8):1313-27.
Species: Mouse
Sample Type: Cell Culture Supernates

IRF-3, IRF-7, and IPS-1 promote host defense against acute human metapneumovirus infection in neonatal mice.
Authors: Spann K, Loh Z, Lynch J, Ullah A, Zhang V, Baturcam E, Werder R, Khajornjiraphan N, Rudd P, Loo Y, Suhrbier A, Gale M, Upham J, Phipps S
Am J Pathol, 2014;184(6):1795-806.
Species: Mouse
Sample Type: Homogenized Tissue

Interleukin-15 modulates adipose tissue by altering mitochondrial mass and activity.
Authors: Barra, Nicole G, Palanivel, Rengasam, Denou, Emmanuel, Chew, Marianne, Gillgrass, Amy, Walker, Tina D, Kong, Josh, Richards, Carl D, Jordana, Manel, Collins, Stephen, Trigatti, Bernardo, Holloway, Alison C, Raha, Sandeep, Steinberg, Gregory, Ashkar, Ali A
PLoS ONE, 2014;9(12):e114799.
Species: Mouse
Sample Type: Cell Culture Supernates

Distinct lipid a moieties contribute to pathogen-induced site-specific vascular inflammation.
Authors: Slocum C, Coats S, Hua N, Kramer C, Papadopoulos G, Weinberg E, Gudino C, Hamilton J, Darveau R, Genco C
PLoS Pathog, 2014;10(7):e1004215.
Species: Mouse
Sample Type: Cell Culture Supernates

Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection.
PLoS ONE, 2014;9(12):e114884.
Species: Mouse
Sample Type: Tissue Homogenates

Induction of type I interferon signaling determines the relative pathogenicity of Staphylococcus aureus strains.
Authors: Parker D, Planet P, Soong G, Narechania A, Prince A
PLoS Pathog, 2014;10(2):e1003951.
Species: Mouse
Sample Type: BALF

Pseudomonas aeruginosa quorum-sensing molecule homoserine lactone modulates inflammatory signaling through PERK and eI-F2alpha.
Authors: Grabiner M, Fu Z, Wu T, Barry K, Schwarzer C, Machen T
J Immunol, 2014;193(3):1459-67.
Species: Mouse
Sample Type: Cell Culture Supernates

Circadian clock function is disrupted by environmental tobacco/cigarette smoke, leading to lung inflammation and injury via a SIRT1-BMAL1 pathway.
Authors: Hwang J, Sundar I, Yao H, Sellix M, Rahman I
FASEB J, 2014;28(1):176-94.
Species: Mouse
Sample Type: Tissue Homgenates

A TNF-alpha-CCL20-CCR6 axis regulates Nod1-induced B cell responses.
Authors: Paradis M, Mindt B, Duerr C, Rojas O, Ng D, Boulianne B, McCarthy D, Yu M, Summers deLuca L, Ward L, Waldron J, Philpott D, Gommerman J, Fritz J
J Immunol, 2014;192(6):2787-99.
Species: Mouse
Sample Type: Serum

Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes.
Authors: Dreymueller D, Martin C, Schumacher J, Groth E, Boehm J, Reiss L, Uhlig S, Ludwig A
J Immunol, 2014;192(2):722-31.
Species: Mouse
Sample Type: Cell Culture Supernates

Mannose receptor 1 mediates cellular uptake and endosomal delivery of CpG-motif containing oligodeoxynucleotides.
Authors: Moseman, Annie Pa, Moseman, E Ashley, Schworer, Stephen, Smirnova, Irina, Volkova, Tatyana, von Andrian, Ulrich, Poltorak, Alexande
J Immunol, 2013;191(11):5615-24.
Species: Mouse
Sample Type: cell culture supernate

Effect of secretin on preadipocyte, differentiating and mature adipocyte functions.
Authors: Miegueu P, Cianflone K, Richard D, St-Pierre D
Int J Obes (Lond), 2013;37(3):366-74.
Species: Mouse
Sample Type: cell supernates

alpha1-Antitrypsin promotes SPLUNC1-mediated lung defense against Pseudomonas aeruginosa infection in mice.
Authors: Jiang D, Persinger R, Wu Q, Gross A, Chu H
Respir Res, 2013;14(0):122.
Species: Mouse
Sample Type: BALF

The lung inflammation and skeletal muscle wasting induced by subchronic cigarette smoke exposure are not altered by a high-fat diet in mice.
Authors: Hansen, Michelle, Chen, Hui, Jones, Jessica, Langenbach, Shenna Y, Vlahos, Ross, Gualano, Rosa C, Morris, Margaret, Anderson, Gary P
PLoS ONE, 2013;8(11):e80471.
Species: Mouse
Sample Type: Tissue Homogenates

Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C
Infect. Immun., 2012;80(1):100-9.
Species: Mouse
Sample Type: Serum

The role of alveolar epithelial cells in initiating and shaping pulmonary immune responses: communication between innate and adaptive immune systems.
Authors: Chuquimia OD, Petursdottir DH, Rahman MJ, Hartl K, Singh M, Fernandez C
PLoS ONE, 2012;7(2):e32125.
Species: Mouse
Sample Type: Cell Culture Supernates

Fecal lipocalin 2, a sensitive and broadly dynamic non-invasive biomarker for intestinal inflammation.
PLoS ONE, 2012;7(9):e44328.
Species: Mouse
Sample Type: Serum

Macrophage Dectin-1 Expression Is Controlled by Leukotriene B4 via a GM-CSF/PU.1 Axis.
Authors: Serezani CH, Kane S, Collins L
J. Immunol., 2012;189(2):906-15.
Species: Mouse
Sample Type: BALF

Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33.
J. Exp. Med., 2012;209(8):1505-17.
Species: Mouse
Sample Type: Cell Culture Supernates

Altered regulation of Toll-like receptor responses impairs antibacterial immunity in the allergic lung.
Authors: Habibzay, M, Saldana, J I, Goulding, J, Lloyd, C M, Hussell, T
Mucosal Immunol, 2012;5(5):524-34.
Species: Mouse
Sample Type: BALF

Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, Is crucial for murine asthma.
Authors: Suzukawa M, Morita H, Nambu A, Arae K, Shimura E, Shibui A, Yamaguchi S, Suzukawa K, Nakanishi W, Oboki K, Kajiwara N, Ohno T, Ishii A, Korner H, Cua D, Suto H, Yoshimoto T, Iwakura Y, Yamasoba T, Ohta K, Sudo K, Saito H, Okumura K, Broide D, Matsumoto K, Nakae S
J Immunol, 2012;189(7):3641-52.
Species: Mouse
Sample Type: BALF

Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis.
J. Immunol., 2012;189(4):1911-9.
Species: Mouse
Sample Type: Serum

IL-22 signaling contributes to West Nile encephalitis pathogenesis.
Authors: Wang, Penghua, Bai, Fengwei, Zenewicz, Lauren A, Dai, Jianfeng, Gate, David, Cheng, Gong, Yang, Long, Qian, Feng, Yuan, Xiaoling, Montgomery, Ruth R, Flavell, Richard, Town, Terrence, Fikrig, Erol
PLoS ONE, 2012;7(8):e44153.
Species: Mouse
Sample Type: Plasma

The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa.
Authors: Moalli F, Paroni M, Veliz Rodriguez T, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S, Nebuloni M, Mantovani A, Bragonzi A, Garlanda C
J. Immunol., 2011;186(9):5425-34.
Species: Mouse
Sample Type: Tissue Homogenates

Local delivery of GM-CSF protects mice from lethal pneumococcal pneumonia.
Authors: Steinwede K, Tempelhof O, Bolte K, Maus R, Bohling J, Ueberberg B, Langer F, Christman JW, Paton JC, Ask K, Maharaj S, Kolb M, Gauldie J, Welte T, Maus UA
J. Immunol., 2011;187(10):5346-56.
Species: Mouse
Sample Type: BALF

Recombinant human tissue factor pathway inhibitor exerts anticoagulant, anti-inflammatory and antimicrobial effects in murine pneumococcal pneumonia.
Authors: Van Den Boogaard FE, Brands X, Schultz MJ, Levi M, Roelofs JJ, Van t Veer C, van der Poll T
J. Thromb. Haemost., 2011;9(1):122-32.

Leukocyte ADAM17 Regulates Acute Pulmonary Inflammation.
Authors: Arndt PG, Strahan B, Wang Y, Long C, Horiuchi K, Walcheck B
PLoS ONE, 2011;6(5):e19938.
Species: Mouse
Sample Type: BALF

Innate immune responses to systemic Acinetobacter baumannii infection in mice: neutrophils, but not interleukin-17, mediate host resistance.
Authors: Breslow JM, Meissler JJ, Hartzell RR
Infect. Immun., 2011;79(8):3317-27.
Species: Mouse
Sample Type: plueral exudate fluid

A natural protective function of invariant NKT cells in a mouse model of innate-cell-driven lung inflammation.
Authors: Bourgeois EA, Levescot A, Diem S, Chauvineau A, Berges H, Milpied P, Lehuen A, Damotte D, Gombert JM, Schneider E, Girard JP, Gourdy P, Herbelin A
Eur. J. Immunol., 2011;41(2):299-305.
Species: Mouse
Sample Type: BALF

Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein.
Authors: Le Goffic R, Leymarie O, Chevalier C, Rebours E, Da Costa B, Vidic J, Descamps D, Sallenave JM, Rauch M, Samson M, Delmas B
PLoS Pathog., 2011;7(8):e1002202.
Species: Mouse
Sample Type: BALF

Lung-targeted overexpression of the NF-kappaB member RelB inhibits cigarette smoke-induced inflammation.
Authors: McMillan DH, Baglole CJ, Thatcher TH, Maggirwar S, Sime PJ, Phipps RP
Am. J. Pathol., 2011;179(1):125-33.
Species: Mouse
Sample Type: BALF

Chemokine binding protein M3 of murine gammaherpesvirus 68 modulates the host response to infection in a natural host.
Authors: Hughes DJ, Kipar A, Leeming GH, Bennett E, Howarth D, Cummerson JA, Papoula-Pereira R, Flanagan BF, Sample JT, Stewart JP
PLoS Pathog., 2011;7(3):e1001321.
Species: Mouse
Sample Type: Tissue Homogenates

Phosphoinositide 3-kinase gamma plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice.
Authors: Russo RC, Garcia CC, Barcelos LS, Rachid MA, Guabiraba R, Roffe E, Souza AL, Sousa LP, Mirolo M, Doni A, Cassali GD, Pinho V, Locati M, Teixeira MM
J. Leukoc. Biol., 2011;89(2):269-82.
Species: Mouse
Sample Type: Tissue Homogenates

Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity.
Authors: Sellge G, Magalhaes JG, Konradt C, Fritz JH, Salgado-Pabon W, Eberl G, Bandeira A, Di Santo JP, Sansonetti PJ, Phalipon A
J. Immunol., 2010;184(4):2076-85.
Species: Mouse
Sample Type: Cell Culture Supernates

Toll-like receptor 4 mediates the response of epithelial and stromal cells to lipopolysaccharide in the endometrium.
Authors: Sheldon IM, Roberts MH,
PLoS ONE, 2010;5(9):e12906.
Species: Mouse
Sample Type: Cell Culture Supernates

Distinct roles of hepatocyte- and myeloid cell-derived IL-1 receptor antagonist during endotoxemia and sterile inflammation in mice.
Authors: Lamacchia C, Palmer G, Bischoff L, Rodriguez E, Talabot-Ayer D, Gabay C
J. Immunol., 2010;185(0):2516-24.
Species: Mouse
Sample Type: Serum

Impact of adiponectin deficiency on pulmonary responses to acute ozone exposure in mice.
Authors: Zhu M, Hug C, Kasahara DI
Am. J. Respir. Cell Mol. Biol., 2010;43(4):487-97.
Species: Mouse
Sample Type: BALF

Ligands of the receptor for advanced glycation end products, including high-mobility group box 1, limit bacterial dissemination during Escherichia coli peritonitis.
Authors: van Zoelen MA, Achouiti A, Schmidt AM, Yang H, Florquin S, Tracey KJ, van der Poll T
Crit. Care Med., 2010;38(6):1414-22.
Species: Mouse
Sample Type: Peritoneal Fluid

Trimer stability of YadA is critical for virulence of Yersinia enterocolitica.
Authors: Schutz M, Weiss EM, Schindler M, Hallstrom T, Zipfel PF, Linke D, Autenrieth IB
Infect. Immun., 2010;78(6):2677-90.
Species: Mouse
Sample Type: Serum

Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid.
Authors: van Neerven S, Regen T, Wolf D, Nemes A, Johann S, Beyer C, Hanisch UK, Mey J
J. Neurochem., 2010;114(5):1511-26.
Species: Mouse
Sample Type: Cell Culture Supernates

Defective regulation of CXCR2 facilitates neutrophil release from bone marrow causing spontaneous inflammation in severely NF-kappa B-deficient mice.
Authors: von Vietinghoff S, Asagiri M, Azar D
J. Immunol., 2010;185(1):670-8.
Species: Mouse
Sample Type: Plasma

Spatiotemporal expression of chemokines and chemokine receptors in experimental anti-myeloperoxidase antibody-mediated glomerulonephritis.
Authors: van der Veen BS, Petersen AH, Belperio JA, Satchell SC, Mathieson PW, Molema G, Heeringa P
Clin. Exp. Immunol., 2009;158(1):143-53.
Species: Mouse
Sample Type: Tissue Homogenates

IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema.
Authors: Couillin I, Vasseur V, Charron S, Gasse P, Tavernier M, Guillet J, Lagente V, Fick L, Jacobs M, Coelho FR, Moser R, Ryffel B
J. Immunol., 2009;183(12):8195-202.
Species: Mouse
Sample Type: BALF

CCR7 modulates pulmonary and lymph node inflammatory responses in cigarette smoke-exposed mice.
Authors: Demoor T, Bracke KR, Vermaelen KY, Dupont L, Joos GF, Brusselle GG
J. Immunol., 2009;183(12):8186-94.
Species: Mouse
Sample Type: BALF

Trappin-2 promotes early clearance of Pseudomonas aeruginosa through CD14-dependent macrophage activation and neutrophil recruitment.
Authors: Wilkinson TS, Dhaliwal K, Hamilton TW, Lipka AF, Farrell L, Davidson DJ, Duffin R, Morris AC, Haslett C, Govan JR, Gregory CD, Sallenave JM, Simpson AJ
Am. J. Pathol., 2009;174(4):1338-46.
Species: Mouse
Sample Type: BALF

The long pentraxin PTX3 is crucial for tissue inflammation after intestinal ischemia and reperfusion in mice.
Authors: Souza DG, Amaral FA, Fagundes CT, Coelho FM, Arantes RM, Sousa LP, Matzuk MM, Garlanda C, Mantovani A, Dias AA, Teixeira MM
Am. J. Pathol., 2009;174(4):1309-18.
Species: Mouse
Sample Type: Serum

Role of endothelial TLR4 for neutrophil recruitment into central nervous system microvessels in systemic inflammation.
Authors: Zhou H, Andonegui G, Wong CH, Kubes P
J. Immunol., 2009;183(8):5244-50.
Species: Mouse
Sample Type: Plasma

TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia.
Authors: Lagler H, Sharif O, Haslinger I, Matt U, Stich K, Furtner T, Doninger B, Schmid K, Gattringer R, de Vos AF, Knapp S
J. Immunol., 2009;183(3):2027-36.
Species: Mouse
Sample Type: Tissue Homogenates

Matrix metalloproteinase-9 deficiency worsens lung injury in a model of bronchopulmonary dysplasia.
Authors: Lukkarinen H, Hogmalm A, Lappalainen U, Bry K
Am. J. Respir. Cell Mol. Biol., 2009;41(1):59-68.
Species: Mouse
Sample Type: Tissue Homogenates

Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent.
Authors: Doz E, Noulin N, Boichot E, Guenon I, Fick L, Le Bert M, Lagente V, Ryffel B, Schnyder B, Quesniaux VF, Couillin I
J. Immunol., 2008;180(2):1169-78.
Species: Mouse
Sample Type: BALF

An age-associated increase in pulmonary inflammation after burn injury is abrogated by CXCR2 inhibition.
Authors: Nomellini V, Faunce DE, Gomez CR, Kovacs EJ
J. Leukoc. Biol., 2008;83(6):1493-501.

The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature.
Authors: Coelho FM, Pinho V, Amaral FA, Sachs D, Costa VV, Rodrigues DH, Vieira AT, Silva TA, Souza DG, Bertini R, Teixeira AL, Teixeira MM
Arthritis Rheum., 2008;58(8):2329-37.
Species: Mouse
Sample Type: Tissue Homogenates

Scavenging roles of chemokine receptors: chemokine receptor deficiency is associated with increased levels of ligand in circulation and tissues.
Authors: Cardona AE, Sasse ME, Liu L, Cardona SM, Mizutani M, Savarin C, Hu T, Ransohoff RM
Blood, 2008;112(2):256-63.
Species: Mouse
Sample Type: Tissue Homogenates

Methylprednisolone improves lung mechanics and reduces the inflammatory response in pulmonary but not in extrapulmonary mild acute lung injury in mice.
Authors: Leite-Junior JH, Garcia CS, Souza-Fernandes AB, Silva PL, Ornellas DS, Larangeira AP, Castro-Faria-Neto HC, Morales MM, Negri EM, Capelozzi VL, Zin WA, Pelosi P, Bozza PT, Rocco PR
Crit. Care Med., 2008;36(9):2621-8.
Species: Mouse
Sample Type: BALF

MyD88 regulation of Fusarium keratitis is dependent on TLR4 and IL-1R1 but not TLR2.
Authors: Tarabishy AB, Aldabagh B, Sun Y, Imamura Y, Mukherjee PK, Lass JH, Ghannoum MA, Pearlman E
J. Immunol., 2008;181(1):593-600.
Species: Mouse
Sample Type: Tissue Homogenates

Adenosine receptors in regulation of dendritic cell differentiation and function.
Authors: Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM
Blood, 2008;112(5):1822-31.
Species: Mouse
Sample Type: Cell Culture Supernates

Modulation of ozone-induced airway hyperresponsiveness and inflammation by interleukin-13.
Authors: Williams AS, Nath P, Leung SY, Khorasani N, McKenzie AN, Adcock IM, Chung KF
Eur. Respir. J., 2008;32(3):571-8.
Species: Mouse
Sample Type: BALF

Involvement of vitronectin in lipopolysaccaride-induced acute lung injury.
Authors: Tsuruta Y, Park YJ, Siegal GP, Liu G, Abraham E
J. Immunol., 2007;179(10):7079-86.
Species: Mouse
Sample Type: Tissue Homogenates

Clara cells impact the pulmonary innate immune response to LPS.
Authors: Elizur A, Adair-Kirk TL, Kelley DG, Griffin GL, deMello DE, Senior RM
Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(2):L383-92.
Species: Mouse
Sample Type: Cell Culture Supernates

Role of mesothelial cell-derived granulocyte colony-stimulating factor in interleukin-17-induced neutrophil accumulation in the peritoneum.
Authors: Witowski J, Ksiazek K, Warnecke C, Kuzlan M, Korybalska K, Tayama H, Wisniewska-Elnur J, Pawlaczyk K, Trominska J, Breborowicz A, Jorres A
Kidney Int., 2007;71(6):514-25.
Species: Mouse
Sample Type: Peritoneal Lavage

Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
Immunity, 2007;26(4):445-59.
Species: Mouse
Sample Type: Cell Culture Supernates

Transgenic blockade of interleukin 6 transsignaling abrogates inflammation.
Authors: Rabe B, Chalaris A, May U, Waetzig GH, Seegert D, Williams AS, Jones SA, Rose-John S, Scheller J
Blood, 2007;111(3):1021-8.
Species: Mouse
Sample Type: Air Pouch Exudate

IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice.
Authors: Smith E, Zarbock A, Stark MA, Burcin TL, Bruce AC, Foley P, Ley K
J. Immunol., 2007;179(12):8274-9.
Species: Mouse
Sample Type: Serum

IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice.
Authors: Gasse P, Mary C, Guenon I, Noulin N, Charron S, Schnyder-Candrian S, Schnyder B, Akira S, Quesniaux VF, Lagente V, Ryffel B, Couillin I
J. Clin. Invest., 2007;117(12):3786-99.
Species: Mouse
Sample Type: BALF

Role of Toll-like receptor 2 in recognition of Legionella pneumophila in a murine pneumonia model.
Authors: Fuse ET, Tateda K, Kikuchi Y, Matsumoto T, Gondaira F, Azuma A, Kudoh S, Standiford TJ, Yamaguchi K
J. Med. Microbiol., 2007;56(0):305-12.
Species: Mouse
Sample Type: Tissue Homogenates

Deletion of TLR5 results in spontaneous colitis in mice.
Authors: Vijay-Kumar M, Sanders CJ, Taylor RT, Kumar A, Aitken JD, Sitaraman SV, Neish AS, Uematsu S, Akira S, Williams IR, Gewirtz AT
J. Clin. Invest., 2007;117(12):3909-21.
Species: Mouse
Sample Type: Serum

Differential involvement of TLR2 and TLR4 in host survival during pulmonary infection with Chlamydia pneumoniae.
Authors: Rodriguez N, Wantia N, Fend F, Durr S, Wagner H, Miethke T
Eur. J. Immunol., 2006;36(5):1145-55.
Species: Mouse
Sample Type: Tissue Homogenates

Toll-like receptor 4 signaling leads to neutrophil migration impairment in polymicrobial sepsis.
Authors: Alves-Filho JC, de Freitas A, Russo M, Cunha FQ
Crit. Care Med., 2006;34(2):461-70.
Species: Mouse
Sample Type: Tissue Homogenates

Interleukin-17 is a negative regulator of established allergic asthma.
Authors: Schnyder-Candrian S, Togbe D, Couillin I, Mercier I, Brombacher F, Quesniaux V, Fossiez F, Ryffel B, Schnyder B
J. Exp. Med., 2006;203(12):2715-25.
Species: Mouse
Sample Type: Tissue Homogenates

Increased pulmonary responses to acute ozone exposure in obese db/db mice.
Authors: Lu FL, Johnston RA, Flynt L, Theman TA, Terry RD, Schwartzman IN, Lee A, Shore SA
Am. J. Physiol. Lung Cell Mol. Physiol., 2006;290(5):L856-65.
Species: Mouse
Sample Type: Serum

Flagellin suppresses epithelial apoptosis and limits disease during enteric infection.
Authors: Vijay-Kumar M, Wu H, Jones R, Grant G, Babbin B, King TP, Kelly D, Gewirtz AT, Neish AS
Am. J. Pathol., 2006;169(5):1686-700.
Species: Mouse
Sample Type: Serum

Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals.
Authors: Scott P, Ma H, Viriyakosol S, Terkeltaub R, Liu-Bryan R
J. Immunol., 2006;177(9):6370-8.
Species: Mouse
Sample Type: Cell Culture Supernates

Impaired inflammatory angiogenesis, but not leukocyte influx, in mice lacking TNFR1.
Authors: Barcelos LS, Talvani A, Teixeira AS, Vieira LQ, Cassali GD, Andrade SP, Teixeira MM
J. Leukoc. Biol., 2005;78(2):352-8.
Species: Mouse
Sample Type: sponge fluids

Anti-inflammatory activity in the aqueous crude extract of the leaves of Nidularium procerum: A bromeliaceae from the Brazilian coastal rain forest.
Authors: Amendoeira FC, Frutuoso VS, Zanon C, Chedier LM, Figueiredo MR, Kaplan MA, Bandeira-Melo C, Bozza PT, Castro-Faria-Neto HC
Biol. Pharm. Bull., 2005;28(6):1010-5.
Species: Mouse
Sample Type: Pleural Fluid

An essential role for non-bone marrow-derived cells in control of Pseudomonas aeruginosa pneumonia.
Authors: Hajjar AM, Harowicz H, Liggitt HD, Fink PJ, Wilson CB, Skerrett SJ
Am. J. Respir. Cell Mol. Biol., 2005;33(5):470-5.
Species: Mouse
Sample Type: Tissue Homogenates

Tissue inhibitor of metalloproteinase-1 deficiency amplifies acute lung injury in bleomycin-exposed mice.
Authors: Kim KH, Burkhart K, Chen P, Frevert CW, Randolph-Habecker J, Hackman RC, Soloway PD, Madtes DK
Am. J. Respir. Cell Mol. Biol., 2005;33(3):271-9.
Species: Mouse
Sample Type: BALF

Both hemopoietic and resident cells are required for MyD88-dependent pulmonary inflammatory response to inhaled endotoxin.
Authors: Noulin N, Quesniaux VF, Schnyder-Candrian S, Schnyder B, Maillet I, Robert T, Vargaftig BB, Ryffel B, Couillin I
J. Immunol., 2005;175(10):6861-9.
Species: Mouse
Sample Type: BALF

Pyocyanin production by Pseudomonas aeruginosa induces neutrophil apoptosis and impairs neutrophil-mediated host defenses in vivo.
Authors: Allen L, Dockrell DH, Pattery T, Lee DG, Cornelis P, Hellewell PG, Whyte MK
J. Immunol., 2005;174(6):3643-9.
Species: Mouse
Sample Type: BALF

Adenoviral infection decreases mortality from lipopolysaccharide-induced liver failure via induction of TNF-alpha tolerance.
Authors: Yarovinsky TO, Powers LS, Butler NS, Bradford MA, Monick MM, Hunninghake GW
J. Immunol., 2003;171(5):2453-60.
Species: Mouse
Sample Type: Serum