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Mouse IL-17 DuoSet ELISA, 15 Plate (1 KT)

货号: DY421 基本售价: 10120.7 元 规格: 1 KIT

产品信息

概述
货号DY421
别名
CTLA-8; CTLA8cytotoxic T-lymphocyte-associated serine esterase 8; Cytotoxic T-lymphocyte-associated antigen 8; IL17; IL-17; IL17A; IL-17A; IL-17Acytotoxic T-lymphocyte-associated protein 8; IL-17CTLA-8; IL17interleukin-17A; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A
全称Interleukin 17
反应种属Mouse
目标/特异性Please see the product datasheet
性能
供应商R&D Systems
检测类型Solid Phase Sandwich ELISA
Entrez Gene IDs3605 (Human); 16171 (Mouse); 301289 (Rat); 481837 (Canine);
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

AAV8-Mediated Angiotensin-Converting Enzyme 2 Gene Delivery Prevents Experimental Autoimmune Uveitis by Regulating MAPK, NF-?B and STAT3 Pathways
Sci Rep, 2016;6(0):31912.
Species: Mouse
Sample Type: Cell Culture Supernates

Novel Function of Extracellular Matrix Protein 1 in Suppressing Th17 Cell Development in Experimental Autoimmune Encephalomyelitis
Authors: Pan Su
J Immunol, 2016;0(0):.
Species: Mouse
Sample Type: Cell Culture Supernates

Poly-N-acetyl glucosamine production by Staphylococcus epidermidis cells increases their in vivo pro-inflammatory effect
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Type: Peritoneal Exudates

The circadian clock regulates inflammatory arthritis
FASEB J, 2016;0(0):.
Species: Mouse
Sample Type: Serum

Repeated Activation of Lung Invariant NKT Cells Results in Chronic Obstructive Pulmonary Disease-Like Symptoms.
Authors: Tsao C, Tsao P, Chen Y, Chuang Y
PLoS ONE, 2016;11(1):e0147710.
Species: Mouse
Sample Type: BALF

Myelin Oligodendrocyte Glycoprotein induces incomplete tolerance of CD4(+) T cells specific for both a myelin and a neuronal self antigen in mice
Authors: Liliana E Lucca
Eur J Immunol, 2016;0(0):.
Species: Mouse
Sample Type: Cell Culture Supernates

Interleukin-27 Mediates Susceptibility to Visceral Leishmaniasis by Suppressing the IL-17-Neutrophil Response
Authors: Gustavo F S Quirino
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Type: Tissue Homogenates

Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge
Authors: A Savers, O Rasid, M Parlato, M Brock, G Jouvion, B Ryffel, JM Cavaillon, G Eberl, O Ibrahim-Gr
PLoS ONE, 2016;11(4):e0153829.
Species: Mouse
Sample Type: tissue lysates

IL-22 Restrains Tapeworm-Mediated Protection against Experimental Colitis via Regulation of IL-25 Expression
Authors: JL Reyes, MR Fernando, F Lopes, G Leung, NL Mancini, CE Matisz, A Wang, DM McKay
PLoS Pathog, 2016;12(4):e1005481.
Species: Mouse
Sample Type: Cell Culture SupernatesSpleen and MLN

Impact of Histone H1 on the Progression of Allergic Rhinitis and Its Suppression by Neutralizing Antibody in Mice
Authors: T Nakano, R Kamei, T Fujimura, Y Takaoka, A Hori, CY Lai, KC Chiang, Y Shimada, N Ohmori, T Goto, K Ono, CL Chen, S Goto, S Kawamoto
PLoS ONE, 2016;11(4):e0153630.
Species: Mouse
Sample Type: Cell Culture Supernates

A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis.
Authors: Bernard N, Finlay C, Tannahill G, Cassidy J, ONeill L, Mills K
Mucosal Immunol, 2015;8(5):982-92.
Species: Mouse
Sample Type: Tissue Homogenates

Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge.
Authors: Monin L, Griffiths K, Slight S, Lin Y, Rangel-Moreno J, Khader S
Mucosal Immunol, 2015;8(5):1099-109.
Species: Mouse
Sample Type: Cell Culture Supernates

RSV vaccine-enhanced disease is orchestrated by the combined actions of distinct CD4 T cell subsets.
Authors: Knudson C, Hartwig S, Meyerholz D, Varga S
PLoS Pathog, 2015;11(3):e1004757.
Species: Mouse
Sample Type: cell supernates

Obeticholic acid, a synthetic bile acid agonist of the farnesoid X receptor, attenuates experimental autoimmune encephalomyelitis.
Authors: Ho P, Steinman L
Proc Natl Acad Sci U S A, 2015;113(6):1600-5.
Species: Mouse
Sample Type: Cell Culture Supernates

DCIR maintains bone homeostasis by regulating IFN-gamma production in T cells.
Authors: Maruhashi T, Kaifu T, Yabe R, Seno A, Chung S, Fujikado N, Iwakura Y
J Immunol, 2015;194(12):5681-91.
Species: Mouse
Sample Type: Tissue Homogenates

De novo-induced self-antigen-specific Foxp3+ regulatory T cells impair the accumulation of inflammatory dendritic cells in draining lymph nodes.
Authors: Alissafi T, Hatzioannou A, Ioannou M, Sparwasser T, Grun J, Grutzkau A, Verginis P
J Immunol, 2015;194(12):5812-24.
Species: Mouse
Sample Type: Cell Culture Supernates

Genome-wide transcriptional analyses of islet-specific CD4+ T cells identify Idd9 genes controlling diabetogenic T cell function.
Authors: Berry G, Frielle C, Luu T, Salzberg A, Rainbow D, Wicker L, Waldner H
J Immunol, 2015;194(6):2654-63.
Species: Mouse
Sample Type: Cell Culture Supernates

Cholera toxin adjuvant promotes a balanced Th1/Th2/Th17 response independently of IL-12 and IL-17 by acting on Gsalpha in CD11b(+) DCs.
Authors: Mattsson J, Schon K, Ekman L, Fahlen-Yrlid L, Yrlid U, Lycke N
Mucosal Immunol, 2015;8(4):815-27.
Species: Mouse
Sample Type: Cell Culture Supernates

Positional identification of RT1-B (HLA-DQ) as susceptibility locus for autoimmune arthritis.
Authors: Haag S, Tuncel J, Thordardottir S, Mason D, Yau A, Dobritzsch D, Backlund J, Peters E, Holmdahl R
J Immunol, 2015;194(6):2539-50.
Species: Rat
Sample Type: Cell Culture Supernates

Prostaglandin E2 Production and T Cell Function in Mouse Adenovirus Type 1 Infection following Allogeneic Bone Marrow Transplantation.
Authors: McCarthy M, Procario M, Wilke C, Moore B, Weinberg J
PLoS ONE, 2015;10(9):e0139235.
Species: Mouse
Sample Type: Cell Culture Supernates

Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens.
Authors: Kortman G, Mulder M, Richters T, Shanmugam N, Trebicka E, Boekhorst J, Timmerman H, Roelofs R, Wiegerinck E, Laarakkers C, Swinkels D, Bolhuis A, Cherayil B, Tjalsma H
Eur J Immunol, 2015;45(9):2553-67.
Species: Mouse
Sample Type: Cell Culture Supernates

Unexpected Role for Adaptive alphabetaTh17 Cells in Acute Respiratory Distress Syndrome.
Authors: Li J, Melton A, Su G, Hamm D, LaFemina M, Howard J, Fang X, Bhat S, Huynh K, OKane C, Ingram R, Muir R, McAuley D, Matthay M, Sheppard D
J Immunol, 2015;195(1):87-95.
Species: Mouse
Sample Type: BALF

Cooperation between IL-7 Receptor and Integrin alpha2beta1 (CD49b) Drives Th17-Mediated Bone Loss.
Authors: El Azreq M, Arseneault C, Boisvert M, Page N, Allaeys I, Poubelle P, Tessier P, Aoudjit F
J Immunol, 2015;195(9):4198-209.
Species: Mouse
Sample Type: Cell Culture Supernates

Role of a Novel Human Leukocyte Antigen-DQA1*01:02;DRB1*15:01 Mixed Isotype Heterodimer in the Pathogenesis of "Humanized" Multiple Sclerosis-like Disease.
Authors: Kaushansky N, Eisenstein M, Boura-Halfon S, Hansen B, Nielsen C, Milo R, Zeilig G, Lassmann H, Altmann D, Ben-Nun A
J Biol Chem, 2015;290(24):15260-78.
Species: Mouse
Sample Type: Cell Culture Supernates

Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection.
Authors: Brown A, Murphy A, Lalor S, Leech J, OKeeffe K, Mac Aogain M, OHalloran D, Lacey K, Tavakol M, Hearnden C, Fitzgerald-Hughes D, Humphreys H, Fennell J, van Wamel W, Foster T, Geoghegan J, Lavelle E, Rogers T, McLoughlin R
PLoS Pathog, 2015;11(11):e1005226.
Species: Mouse
Sample Type: Cell Culture Supernates

IFN-gamma-producing and IL-17-producing gammadelta T cells differentiate at distinct developmental stages in murine fetal thymus.
Authors: Shibata K, Yamada H, Nakamura M, Hatano S, Katsuragi Y, Kominami R, Yoshikai Y
J Immunol, 2014;192(5):2210-8.
Species: Mouse
Sample Type: Cell Culture Supernates

IL-27 and IL-12 oppose pro-inflammatory IL-23 in CD4+ T cells by inducing Blimp1.
Authors: Heinemann C, Heink S, Petermann F, Vasanthakumar A, Rothhammer V, Doorduijn E, Mitsdoerffer M, Sie C, Prazeres da Costa O, Buch T, Hemmer B, Oukka M, Kallies A, Korn T
Nat Commun, 2014;5(0):3770.
Species: Mouse
Sample Type: Cell Culture Supernates

Pulmonary immune responses to 2009 pandemic influenza A (H1N1) virus in mice.
Authors: Lv J, Wang D, Hua Y, Pei S, Wang J, Hu W, Wang X, Jia N, Jiang Q
BMC Infect Dis, 2014;14(0):197.
Species: Mouse
Sample Type: Tissue Homogenates

IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis.
Authors: Hams, Emily, Armstrong, Michelle, Barlow, Jillian, Saunders, Sean P, Schwartz, Christia, Cooke, Gordon, Fahy, Ruairi J, Crotty, Thomas B, Hirani, Nikhil, Flynn, Robin J, Voehringer, David, McKenzie, Andrew N, Donnelly, Seamas C, Fallon, Padraic
Proc Natl Acad Sci U S A, 2014;111(1):367-72.
Species: Mouse
Sample Type: Tissue Homogenates

MyD88 signaling regulates both host defense and immunopathogenesis during pneumocystis infection.
Authors: Bello-Irizarry S, Wang J, Johnston C, Gigliotti F, Wright T
J Immunol, 2014;192(1):282-92.
Species: Mouse
Sample Type: BALF

Signaling via tumor necrosis factor receptor 1 but not Toll-like receptor 2 contributes significantly to hydrosalpinx development following Chlamydia muridarum infection.
Authors: Dong X, Liu Y, Chang X, Lei L, Zhong G
Infect Immun, 2014;82(5):1833-9.
Species: Mouse
Sample Type: Cell Culture Supernates

A ThPOK-LRF transcriptional node maintains the integrity and effector potential of post-thymic CD4+ T cells.
Authors: Vacchio M, Wang L, Bouladoux N, Carpenter A, Xiong Y, Williams L, Wohlfert E, Song K, Belkaid Y, Love P, Bosselut R
Nat Immunol, 2014;15(10):947-56.
Species: Mouse
Sample Type: Cell Culture Supernates

Subcomponent vaccine based on CTA1-DD adjuvant with incorporated UreB class II peptides stimulates protective Helicobacter pylori immunity.
Authors: Nedrud J, Bagheri N, Schon K, Xin W, Bergroth H, Eliasson D, Lycke N
PLoS ONE, 2013;8(12):e83321.
Species: Mouse
Sample Type: Cell Culture Supernates

Epithelial NF-kappaB orchestrates house dust mite-induced airway inflammation, hyperresponsiveness, and fibrotic remodeling.
Authors: Tully J, Hoffman S, Lahue K, Nolin J, Anathy V, Lundblad L, Daphtary N, Aliyeva M, Black K, Dixon A, Poynter M, Irvin C, Janssen-Heininger Y
J Immunol, 2013;191(12):5811-21.
Species: Mouse
Sample Type: Tissue Homogenates

Rac2-deficiency leads to exacerbated and protracted colitis in response to Citrobacter rodentium infection.
Authors: Fattouh R, Guo C, Lam G, Gareau M, Ngan B, Glogauer M, Muise A, Brumell J
PLoS ONE, 2013;8(4):e61629.
Species: Mouse
Sample Type: Cell culture supernatant

Exposure to atmospheric particulate matter enhances Th17 polarization through the aryl hydrocarbon receptor.
Authors: van Voorhis, Michael, Knopp, Samantha, Julliard, Walker, Fechner, John H, Zhang, Xiaoji, Schauer, James J, Mezrich, Joshua D
PLoS ONE, 2013;8(12):e82545.
Species: Mouse
Sample Type: cell culture supernate

Preconditioning of microglia by alpha-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation.
Authors: Roodveldt C, Labrador-Garrido A, Gonzalez-Rey E, Lachaud C, Guilliams T, Fernandez-Montesinos R, Benitez-Rondan A, Robledo G, Hmadcha A, Delgado M, Dobson C, Pozo D
PLoS ONE, 2013;8(11):e79160.
Species: Mouse
Sample Type: Cell Culture Supernates

Immune Modulation Mediated by Cryptococcal Laccase Promotes Pulmonary Growth and Brain Dissemination of Virulent Cryptococcus neoformans in Mice.
Authors: Qiu Y, Davis M, Dayrit J, Hadd Z, Meister D, Osterholzer J, Williamson P, Olszewski M
PLoS ONE, 2012;7(10):e47853.
Species: Mouse
Sample Type: Cell Culture Supernates

Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C
Infect. Immun., 2012;80(1):100-9.
Species: Mouse
Sample Type: Serum

LXR-mediated inhibition of CD4+ T helper cells.
Authors: Solt L, Kamenecka T, Burris T
PLoS ONE, 2012;7(9):e46615.
Species: Mouse
Sample Type: Cell Culture Supernates

Macrophage Dectin-1 Expression Is Controlled by Leukotriene B4 via a GM-CSF/PU.1 Axis.
Authors: Serezani CH, Kane S, Collins L
J. Immunol., 2012;189(2):906-15.
Species: Mouse
Sample Type: BALF

Interleukin-23-mediated inflammation in Pseudomonas aeruginosa pulmonary infection.
Authors: Dubin PJ, Martz A, Eisenstatt JR, Fox MD, Logar A, Kolls JK
Infect. Immun., 2012;80(1):398-409.
Species: Mouse
Sample Type: BALF

Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.
Authors: Jones GW, Stumhofer JS, Foster T, Twohig JP, Hertzog P, Topley N, Williams AS, Hunter CA, Jenkins BJ, Wang EC, Jones SA
FASEB J., 2011;25(1):409-19.
Species: Mouse
Sample Type: Cell Culture Supernates

IL-33-responsive lineage- CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs.
Authors: Bartemes KR, Iijima K, Kobayashi T, Kephart GM, McKenzie AN, Kita H
J. Immunol., 2011;188(3):1503-13.
Species: Mouse
Sample Type: Cell Culture Supernates

Natural IgM is required for suppression of inflammatory arthritis by apoptotic cells.
Authors: Notley CA, Brown MA, Wright GP, Ehrenstein MR
J. Immunol., 2011;186(8):4967-72.
Species: Mouse
Sample Type: Cell Culture Supernates

The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa.
Authors: Moalli F, Paroni M, Veliz Rodriguez T, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S, Nebuloni M, Mantovani A, Bragonzi A, Garlanda C
J. Immunol., 2011;186(9):5425-34.
Species: Mouse
Sample Type: Tissue Homogenates

The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.
Authors: El-Behi M, Ciric B, Dai H
Nat. Immunol., 2011;12(6):568-75.
Species: Mouse
Sample Type: Cell Culture Supernates

CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition.
Authors: Barber DL, Mayer-Barber KD, Feng CG
J. Immunol., 2011;186(3):1598-607.
Species: Mouse
Sample Type: BALF

Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in mice.
Authors: Nel HJ, Hams E, Saunders SP
J. Immunol., 2011;186(8):4631-9.
Species: Mouse
Sample Type: Cell Culture Supernates

Innate immune responses to systemic Acinetobacter baumannii infection in mice: neutrophils, but not interleukin-17, mediate host resistance.
Authors: Breslow JM, Meissler JJ, Hartzell RR
Infect. Immun., 2011;79(8):3317-27.
Species: Mouse
Sample Type: plueral exudate fluid

Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells.
Authors: Jones GW, McLoughlin RM, Hammond VJ, Parker CR, Williams JD, Malhotra R, Scheller J, Williams AS, Rose-John S, Topley N, Jones SA
J. Immunol., 2010;184(4):2130-9.
Species: Mouse
Sample Type: Cell Culture Supernates

A critical role for C5L2 in the pathogenesis of experimental allergic asthma.
Authors: Zhang X, Schmudde I, Laumonnier Y, Pandey MK, Clark JR, Konig P, Gerard NP, Gerard C, Wills-Karp M, Kohl J
J. Immunol., 2010;185(11):6741-52.
Species: Mouse
Sample Type: Cell Culture Supernates

IL-27 mediates the response to IFN-beta therapy in multiple sclerosis patients by inhibiting Th17 cells.
Authors: Sweeney CM, Lonergan R, Basdeo SA, Kinsella K, Dungan LS, Higgins SC, Kelly PJ, Costelloe L, Tubridy N, Mills KH, Fletcher JM
Brain Behav. Immun., 2010;0(0):.
Species: Mouse
Sample Type: Cell Culture Supernates

Importance of TLR2 in the direct response of T lymphocytes to Schistosoma mansoni antigens.
Authors: Burton OT, Gibbs S, Miller N, Jones FM, Wen L, Dunne DW, Cooke A, Zaccone P
Eur. J. Immunol., 2010;40(8):2221-9.
Species: Mouse
Sample Type: Cell Culture Supernates

Chronic cigarette smoke exposure generates pathogenic T cells capable of driving COPD-like disease in Rag2-/- mice.
Authors: Motz GT, Eppert BL, Wesselkamper SC, Flury JL, Borchers MT
Am. J. Respir. Crit. Care Med., 2010;181(11):1223-33.
Species: Mouse
Sample Type: BALF

Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity.
Authors: Sellge G, Magalhaes JG, Konradt C, Fritz JH, Salgado-Pabon W, Eberl G, Bandeira A, Di Santo JP, Sansonetti PJ, Phalipon A
J. Immunol., 2010;184(4):2076-85.
Species: Mouse
Sample Type: Cell Culture Supernates

IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice.
Authors: Cho JS, Pietras EM, Garcia NC, Ramos RI, Farzam DM, Monroe HR, Magorien JE, Blauvelt A, Kolls JK, Cheung AL, Cheng G, Modlin RL, Miller LS
J. Clin. Invest., 2010;120(5):1762-73.
Species: Mouse
Sample Type: Cell Culture Supernates

Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses.
Authors: Ishigame H, Kakuta S, Nagai T, Kadoki M, Nambu A, Komiyama Y, Fujikado N, Tanahashi Y, Akitsu A, Kotaki H, Sudo K, Nakae S, Sasakawa C, Iwakura Y
Immunity, 2009;30(1):108-19.
Species: Mouse
Sample Type: Whole Tissue

CCR5 is involved in resolution of inflammation in proteoglycan-induced arthritis.
Authors: Doodes PD, Cao Y, Hamel KM, Wang Y, Rodeghero RL, Kobezda T, Finnegan A
Arthritis Rheum., 2009;60(10):2945-53.
Species: Mouse
Sample Type: Synovial Fluid

Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis.
Authors: Siegemund S, Schutze N, Schulz S, Wolk K, Nasilowska K, Straubinger RK, Sabat R, Alber G
Int. Immunol., 2009;21(5):555-65.
Species: Mouse
Sample Type: Peritoneal Lavage

CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1.
Authors: Han Y, Guo Q, Zhang M, Chen Z, Cao X
J. Immunol., 2009;182(1):111-20.
Species: Mouse
Sample Type: Cell Culture Supernates

Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities.
Authors: Rickel EA, Siegel LA, Yoon BR, Rottman JB, Kugler DG, Swart DA, Anders PM, Tocker JE, Comeau MR, Budelsky AL
J. Immunol., 2008;181(6):4299-310.
Species: Mouse
Sample Type: BALF

Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis.
Authors: Kaya Z, Goser S, Buss SJ, Leuschner F, Ottl R, Li J, Volkers M, Zittrich S, Pfitzer G, Rose NR, Katus HA
Circulation, 2008;118(20):2063-72.
Species: Mouse
Sample Type: Cell Culture Supernates

Interferon-gamma regulates idiopathic pneumonia syndrome, a Th17+CD4+ T-cell-mediated graft-versus-host disease.
Authors: Mauermann N, Burian J, von Garnier C, Dirnhofer S, Germano D, Schuett C, Tamm M, Bingisser R, Eriksson U, Hunziker L
Am. J. Respir. Crit. Care Med., 2008;178(4):379-88.
Species: Mouse
Sample Type: Cell Culture Supernates

Amelioration of delayed-type hypersensitivity responses by IL-27 administration.
Authors: Miyazaki Y, Shimanoe Y, Wang S, Yoshida H
Biochem. Biophys. Res. Commun., 2008;373(3):397-402.
Species: Mouse
Sample Type: Cell Culture Supernates

Protective immunity to systemic infection with attenuated Salmonella enterica serovar enteritidis in the absence of IL-12 is associated with IL-23-dependent IL-22, but not IL-17.
Authors: Schulz SM, Kohler G, Schutze N, Knauer J, Straubinger RK, Chackerian AA, Witte E, Wolk K, Sabat R, Iwakura Y, Holscher C, Muller U, Kastelein RA, Alber G
J. Immunol., 2008;181(11):7891-901.
Species: Mouse
Sample Type: Serum

Tyk2-signaling plays an important role in host defense against Escherichia coli through IL-23-induced IL-17 production by gammadelta T cells.
Authors: Nakamura R, Shibata K, Yamada H, Shimoda K, Nakayama K, Yoshikai Y
J. Immunol., 2008;181(3):2071-5.
Species: Mouse
Sample Type: Cell Culture Supernates

Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection.
Authors: Bozza S, Zelante T, Moretti S, Bonifazi P, DeLuca A, DAngelo C, Giovannini G, Garlanda C, Boon L, Bistoni F, Puccetti P, Mantovani A, Romani L
J. Immunol., 2008;180(6):4022-31.
Species: Mouse
Sample Type: Cell Culture Supernates

CD8+ T cells are not required for vaccine-induced immunity against Leishmania amazonensis in IL-12/23P40(-/-) C57BL/6 mice.
Authors: Hernandez Sanabria MX, Afonso LC, Golgher D, Tafuri WL, Vieira LQ
Microbes Infect., 2007;9(9):1124-34.
Species: Mouse
Sample Type: Cell Culture Supernates

Suppressive effect of IL-27 on encephalitogenic Th17 cells and the effector phase of experimental autoimmune encephalomyelitis.
Authors: Fitzgerald DC, Ciric B, Touil T, Harle H, Grammatikopolou J, Das Sarma J, Gran B, Zhang GX, Rostami A
J. Immunol., 2007;179(5):3268-75.
Species: Mouse
Sample Type: Cell Culture Supernates

IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice.
Authors: Smith E, Zarbock A, Stark MA, Burcin TL, Bruce AC, Foley P, Ley K
J. Immunol., 2007;179(12):8274-9.
Species: Mouse
Sample Type: Serum

T-bet regulates the fate of Th1 and Th17 lymphocytes in autoimmunity.
Authors: Gocke AR, Cravens PD, Ben LH, Hussain RZ, Northrop SC, Racke MK, Lovett-Racke AE
J. Immunol., 2007;178(3):1341-8.
Species: Mouse
Sample Type: Cell Culture Supernates

Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
Immunity, 2007;26(4):445-59.
Species: Mouse
Sample Type: Cell Culture Supernates

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells.
Authors: Fitzgerald DC, Zhang GX, El-Behi M, Fonseca-Kelly Z, Li H, Yu S, Saris CJ, Gran B, Ciric B, Rostami A
Nat. Immunol., 2007;8(12):1372-9.
Species: Mouse
Sample Type: Cell Culture Supernates

Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 production.
Authors: Shibata K, Yamada H, Hara H, Kishihara K, Yoshikai Y
J. Immunol., 2007;178(7):4466-72.
Species: Mouse
Sample Type: Peritoneal Fluid

Interleukin-17 is a negative regulator of established allergic asthma.
Authors: Schnyder-Candrian S, Togbe D, Couillin I, Mercier I, Brombacher F, Quesniaux V, Fossiez F, Ryffel B, Schnyder B
J. Exp. Med., 2006;203(12):2715-25.
Species: Mouse
Sample Type: Cell Culture Supernates

背景The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.
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