| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment
EMBO Mol Med, 2016;0(0):.
Species: Mouse
Sample Type: Plasma
Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge
Authors: A Savers, O Rasid, M Parlato, M Brock, G Jouvion, B Ryffel, JM Cavaillon, G Eberl, O Ibrahim-Gr
PLoS ONE, 2016;11(4):e0153829.
Species: Mouse
Sample Type: tissue lysates
Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor
Sci Rep, 2016;6(0):26490.
Species: Mouse
Sample Type: Tissue Homogenates
Epidermal RAF prevents allergic skin disease
Elife, 2016;5(0):.
Species: Mouse
Sample Type: Serum
Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection.
Authors: Zhao Y, Olonisakin T, Xiong Z, Hulver M, Sayeed S, Yu M, Gregory A, Kochman E, Chen B, Mallampalli R, Sun M, Silverstein R, Stolz D, Shapiro S, Ray A, Ray P, Lee J
Mucosal Immunol, 2015;8(4):896-905.
Species: Mouse
Sample Type: Tissue Homogenates
Regulation of adult hematopoiesis by the a disintegrin and metalloproteinase 10 (ADAM10).
Authors: Weber S, Wetzel S, Prox J, Lehmann T, Schneppenheim J, Donners M, Saftig P
Biochem Biophys Res Commun, 2013;442(3):234-41.
Species: Mouse
Sample Type: Plasma
The interaction between C5a and both C5aR and C5L2 receptors is required for production of G-CSF during acute inflammation.
Authors: Bosmann M, Haggadone M, Zetoune F, Sarma J, Ward P
Eur J Immunol, 2013;43(7):1907-13.
Species: Mouse
Sample Type: Plasma
Defective regulation of CXCR2 facilitates neutrophil release from bone marrow causing spontaneous inflammation in severely NF-kappa B-deficient mice.
Authors: von Vietinghoff S, Asagiri M, Azar D
J. Immunol., 2010;185(1):670-8.
Species: Mouse
Sample Type: Plasma
IL-17A controls IL-17F production and maintains blood neutrophil counts in mice.
Authors: von Vietinghoff S, Ley K
J. Immunol., 2009;183(2):865-73.
Species: Mouse
Sample Type: Cell Culture Supernates
Role of mesothelial cell-derived granulocyte colony-stimulating factor in interleukin-17-induced neutrophil accumulation in the peritoneum.
Authors: Witowski J, Ksiazek K, Warnecke C, Kuzlan M, Korybalska K, Tayama H, Wisniewska-Elnur J, Pawlaczyk K, Trominska J, Breborowicz A, Jorres A
Kidney Int., 2007;71(6):514-25.
Species: Mouse
Sample Type: Peritoneal Lavage
IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice.
Authors: Smith E, Zarbock A, Stark MA, Burcin TL, Bruce AC, Foley P, Ley K
J. Immunol., 2007;179(12):8274-9.
Species: Mouse
Sample Type: Serum
Choosing the frequency of deep inflation in mice: balancing recruitment against ventilator-induced lung injury.
Authors: Allen GB, Suratt BT, Rinaldi L, Petty JM, Bates JH
Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(4):L710-7.
Species: Mouse
Sample Type: BALF
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| 背景 | G-CSF (granulocyte-colony stimulating factor) is a secreted glycoprotein that regulates the proliferation, differentiation, and activation of neutrophilic granulocyte lineage cells. It also enhances M-CSF induced monocyte differentiation and the proliferation of Th2-inducing dendritic cells. G-CSF promotes the development of T cell immune tolerance as well as tissue recovery following myocardial infarction and cerebral ischemia. It signals through G-CSF R/CD114 on monocytes, neutrophils, megakaryocytes, platelets, myeloid progenitors, trophoblasts and placenta, endothelial cells, and various tumor cell types. Mutations in G-CSF R are associated with congenital neutropenia. |
