| 货号 | DY2644 |
| 别名 | Gas1; GAS-1; growth arrest-specific 1; Growth arrest-specific gene-1; growth arrest-specific protein 1 | 全称 | Growth-arrest-specific Protein 1 |
| 反应种属 | Mouse |
| 目标/特异性 | Please see the product datasheet |
| 供应商 | R&D Systems |
| 检测类型 | Solid Phase Sandwich ELISA |
| Entrez Gene IDs | 2619 (Human); 14451 (Mouse); |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Growth arrest-specific protein 1 is a novel endogenous inhibitor of glomerular cell activation and proliferation. | |
| 背景 | The growth arrest-specific genes are related by their induction following cellular stress. Gas1 is a GPI-linked membrane glycoprotein that blocks entry to S phase cell cycle. Gas1 inhibits cell proliferation, protects endothelial cells from apoptosis, and promotes excitotoxic neuronal death. Gas6 is a vitamin K-dependent protein with a gamma-carboxylated amino terminus (Gla domain), four EGF-like repeats, and C-terminal globulin-like domains. Gas6 is a ligand for the Axl, Dtk, and Mer tyrosine kinase receptors. Gas6 is mitogenic and anti-apoptotic for some cell types and also promotes cell adhesion. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |