Mouse LDL R DuoSet ELISA, 15 Plate (1 KT)
货号：
DY2255 基本售价：
10120.7 元 规格：
1 KIT
产品信息
概述| 货号 | DY2255 |
| 别名 | FH; FHC; LDL R; LDL receptor; LDLCQ2; LDLR; low density lipoprotein receptor; low-density lipoprotein receptor class A domain-containing protein 3; low-density lipoprotein receptor |
全称 | Low Density Lipoprotein Receptor | | 反应种属 | Mouse |
| 目标/特异性 | Please see the product datasheet |
性能| 供应商 | R&D Systems |
| 检测类型 | Solid Phase Sandwich ELISA |
| Entrez Gene IDs | 3949 (Human); 16835 (Mouse); 300438 (Rat); |
| 背景 | LDL R (Low Density Lipoprotein Receptor) is a widely expressed cell surface scavenger receptor. LDL R binds ApoB and ApoE, the apolipoproteins of low- and very low-density lipoproteins (LDL and VLDL), respectively. Hepatocyte LDL R is responsible for endocytosis and clearing of most plasma LDL cholesterol. At the low pH of the endocytic vesicle, it dissociates, allowing degradation of LDL and recycling of LDL R to the cell surface. Lack of LDL R expression or function causes familial hypercholesterolemia (FH). The protease PCSK9 can also cause increased plasma cholesterol by promoting LDL R degradation rather than recycling to the cell surface. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
