RUNX2 Mutation Impairs 1?,25-Dihydroxyvitamin D3 mediated Osteoclastogenesis in Dental Follicle Cells
Authors: XZ Wang, XY Sun, CY Zhang, X Yang, WJ Yan, LH Ge, SG Zheng
Sci Rep, 2016;6(0):24225.
Species: Human
Sample Type: Cell Culture Supernates

Two Consecutive Days of Crossfit Training Affects Pro and Anti-inflammatory Cytokines and Osteoprotegerin without Impairments in Muscle Power
Front Physiol, 2016;7(0):260.
Species: Human
Sample Type: Serum

Association of TRAIL and Its Receptors with Large-Artery Atherosclerotic Stroke.
Authors: Pan X, Pang M, Ma A, Wang K, Zhang Z, Zhong Q, Yang S
PLoS ONE, 2015;10(9):e0136414.
Species: Human
Sample Type: Plasma

Elevated Circulating Osteoprotegerin and Renal Dysfunction Predict 15-Year Cardiovascular and All-Cause Mortality: A Prospective Study of Elderly Women.
Authors: Lewis J, Lim W, Ueland T, Wong G, Zhu K, Lim E, Bollerslev J, Prince R
PLoS ONE, 2015;10(7):e0134266.
Species: Human
Sample Type: Serum

Bindarit, an inhibitor of monocyte chemotactic protein synthesis, protects against bone loss induced by chikungunya virus infection.
Authors: Chen W, Foo S, Taylor A, Lulla A, Merits A, Hueston L, Forwood M, Walsh N, Sims N, Herrero L, Mahalingam S
J Virol, 2015;89(1):581-93.
Species: Human
Sample Type: Serum

Mesenchymal progenitors expressing TRAIL induce apoptosis in sarcomas.
Authors: Grisendi G, Spano C, Dsouza N, Rasini V, Veronesi E, Prapa M, Petrachi T, Piccinno S, Rossignoli F, Burns J, Fiorcari S, Granchi D, Baldini N, Horwitz E, Guarneri V, Conte P, Paolucci P, Dominici M
Stem Cells, 2015;33(3):859-69.
Species: Human
Sample Type: Cell Culture Supernates

Localization of microfibrillar-associated protein 4 (MFAP4) in human tissues: clinical evaluation of serum MFAP4 and its association with various cardiovascular conditions.
Authors: Wulf-Johansson H, Lock Johansson S, Schlosser A, Trommelholt Holm A, Rasmussen L, Mickley H, Diederichsen A, Munkholm H, Poulsen T, Tornoe I, Nielsen V, Marcussen N, Vestbo J, Saekmose S, Holmskov U, Sorensen G
PLoS ONE, 2013;8(12):e82243.
Species: Human
Sample Type: Serum

CCR2+CCR5+ T Cells Produce Matrix Metalloproteinase-9 and Osteopontin in the Pathogenesis of Multiple Sclerosis.
Authors: Sato W, Tomita A, Ichikawa D, Lin Y, Kishida H, Miyake S, Ogawa M, Okamoto T, Murata M, Kuroiwa Y, Aranami T, Yamamura T
J Immunol, 2012;189(10):5057-65.
Species: Human
Sample Type: Cell Culture Supernates

Osteoprotegerin levels are increased in patients with venous thromboembolic disease.
Authors: Rattazzi M, Faggin E, Galliazzo S
J. Thromb. Haemost., 2012;10(6):1183-5.
Species: Human
Sample Type: Serum

Relationship between bone mineral density and serum osteoprotegerin in patients with chronic heart failure.
Authors: Chen Y, Wu Y, Yang W, Wang S, Lee C, Chou N, Hsu R, Lin Y, Lin M, Ho Y, Chen M
PLoS ONE, 2012;7(8):e44242.
Species: Human
Sample Type: Serum

Plasma osteoprotegerin is related to carotid and peripheral arterial disease, but not to myocardial ischemia in type 2 diabetes mellitus.
Authors: Poulsen MK, Nybo M, Dahl J, Hosbond S, Poulsen TS, Johansen A, Hoilund-Carlsen PF, Beck-Nielsen H, Rasmussen LM, Henriksen JE
Cardiovasc Diabetol, 2011;10(0):76.
Species: Human
Sample Type: Plasma

Serum osteoprotegerin is a predictor for incident cardiovascular disease and mortality in a general population: the Tromso Study.
Authors: Vik A, Mathiesen EB, Brox J, Wilsgaard T, Njolstad I, Jorgensen L, Hansen JB
J. Thromb. Haemost., 2011;9(4):638-44.
Species: Human
Sample Type: Serum

Systemic inflammatory markers in COPD: results from the Bergen COPD Cohort Study.
Authors: Eagan TM, Ueland T, Wagner PD, Hardie JA, Mollnes TE, Damas JK, Aukrust P, Bakke PS
Eur. Respir. J., 2010;35(3):540-8.
Species: Human
Sample Type: Plasma

The roles of Wnt signaling modulators Dickkopf-1 (Dkk1) and Dickkopf-2 (Dkk2) and cell maturation state in osteogenesis on microstructured titanium surfaces.
Authors: Olivares-Navarrete R, Hyzy S, Wieland M, Boyan BD, Schwartz Z
Biomaterials, 2010;31(8):2015-24.
Species: Human
Sample Type: Cell Lysates

Conjunctival sac fluid contains elevated levels of soluble TRAIL: implications for the anti-tumoral surveillance of the anterior surface of the eye.
Authors: Secchiero P, Lamberti G, Corallini F, Melloni E, Guarnotta C, Sebastiani A, Zauli G
J. Cell. Physiol., 2009;218(1):199-204.
Species: Human
Sample Type: conjunctival fluid

A single-nucleotide polymorphism in the gene encoding osteoprotegerin is associated with diastolic blood pressure in older men.
Authors: Golledge J, Biros E, Clancy P, Cooper M, Palmer LJ, Norman PE
Am. J. Hypertens., 2009;22(11):1167-70.
Species: Human
Sample Type: Plasma

The liberation of fractalkine in the dorsal horn requires microglial cathepsin S.
Authors: Clark AK, Yip PK, Malcangio M
J. Neurosci., 2009;29(21):6945-54.
Species: Human
Sample Type: Serum

Plasma osteoprotegerin levels predict cardiovascular and all-cause mortality and deterioration of kidney function in type 1 diabetic patients with nephropathy.
Authors: Jorsal A, Tarnow L, Flyvbjerg A, Parving HH, Rossing P, Rasmussen LM
Diabetologia, 2008;51(11):2100-7.
Species: Human
Sample Type: Plasma

Osteoprotegerin released from the vascular wall by heparin mainly derives from vascular smooth muscle cells.
Authors: Nybo M, Rasmussen LM
Atherosclerosis, 2008;0(0):.
Species: Human
Sample Type: Cell Culture Supernates

Lack of observed association between high plasma osteoprotegerin concentrations and ischemic stroke risk in a healthy population.
Authors: Nybo M, Johnsen SP, Dethlefsen C, Overvad K, Tjonneland A, Jorgensen JO, Rasmussen LM
Clin. Chem., 2008;54(12):1969-74.
Species: Human
Sample Type: Plasma

Paracrine inhibition of osteoblast differentiation induced by neuroblastoma cells.
Authors: Granchi D, Baglio SR, Amato I, Giunti A, Baldini N
Int. J. Cancer, 2008;123(7):1526-35.
Species: Human
Sample Type: Cell Culture Supernates

Clinical, radiographic, and biochemical characterization of multiple myeloma patients with osteonecrosis of the jaw.
Authors: Raje N, Woo SB, Hande K, Yap JT, Richardson PG, Vallet S, Treister N, Hideshima T, Sheehy N, Chhetri S, Connell B, Xie W, Tai YT, Szot-Barnes A, Tian M, Schlossman RL, Weller E, Munshi NC, Van Den Abbeele AD, Anderson KC
Clin. Cancer Res., 2008;14(8):2387-95.
Species: Human
Sample Type: Serum

Selective targeting of death receptor 5 circumvents resistance of MG-63 osteosarcoma cells to TRAIL-induced apoptosis.
Authors: Locklin RM, Federici E, Espina B, Hulley PA, Russell RG, Edwards CM
Mol. Cancer Ther., 2007;6(12):3219-28.
Species: Human
Sample Type: Cell Culture Supernates

Soluble receptor activator of nuclear factor-kappa B ligand and risk for cardiovascular disease.
Authors: Kiechl S, Schett G, Schwaiger J, Seppi K, Eder P, Egger G, Santer P, Mayr A, Xu Q, Willeit J
Circulation, 2007;116(4):385-91.
Species: Human
Sample Type: Serum

Differential gene expression in cultured osteoblasts and bone marrow stromal cells from patients with Paget's disease of bone.
Authors: Naot D, Bava U, Matthews B, Callon KE, Gamble GD, Black M, Song S, Pitto RP, Cundy T, Cornish J, Reid IR
J. Bone Miner. Res., 2007;22(2):298-309.
Species: Human
Sample Type: Serum

Heparin induces mobilization of osteoprotegerin into the circulation.
Authors: Vik A, Brodin E, Sveinbjornsson B, Hansen JB
Thromb. Haemost., 2007;98(1):148-54.
Species: Human
Sample Type: Plasma

Therapeutic relevance of osteoprotegerin gene therapy in osteosarcoma: blockade of the vicious cycle between tumor cell proliferation and bone resorption.
Authors: Lamoureux F, Richard P, Wittrant Y, Battaglia S, Pilet P, Trichet V, Blanchard F, Gouin F, Pitard B, Heymann D, Redini F
Cancer Res., 2007;67(15):7308-18.
Species: Mouse
Sample Type: Cell Culture Supernates

Cardiovascular effects of intravenous ghrelin infusion in healthy young men.
Authors: Vestergaard ET, Andersen NH, Hansen TK, Rasmussen LM, Moller N, Sorensen KE, Sloth E, Jorgensen JO
Am. J. Physiol. Heart Circ. Physiol., 2007;293(5):H3020-6.
Species: Human
Sample Type: Serum

B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease.
Authors: Kawai T, Matsuyama T, Hosokawa Y, Makihira S, Seki M, Karimbux NY, Goncalves RB, Valverde P, Dibart S, Li YP, Miranda LA, Ernst CW, Izumi Y, Taubman MA
Am. J. Pathol., 2006;169(3):987-98.
Species: Human
Sample Type: Tissue Homogenates

PAPP-A and osteoprotegerin, together with interleukin-8 and RANTES, are elevated in the peritoneal fluid of women with endometriosis.
Authors: Bersinger NA, von Roten S, Wunder DM, Raio L, Dreher E, Mueller MD
Am. J. Obstet. Gynecol., 2006;195(1):103-8.
Species: Human
Sample Type: Peritoneal Fluid

Gingival fibroblasts are better at inhibiting osteoclast formation than periodontal ligament fibroblasts.
Authors: de Vries TJ, Schoenmaker T, Wattanaroonwong N, van den Hoonaard M, Nieuwenhuijse A, Beertsen W, Everts V
J. Cell. Biochem., 2006;98(2):370-82.
Species: Human
Sample Type: Cell Culture Supernates

Differential expression of RANKL and osteoprotegerin in gingival crevicular fluid of patients with periodontitis.
Authors: Mogi M, Otogoto J, Ota N, Togari A
J. Dent. Res., 2004;83(2):166-9.
Species: Human
Sample Type: Gingival Crevicular Fluid (GCF)

Receptor activator of nuclear factor kappaB ligand (RANKL)/osteoprotegerin (OPG) ratio is increased in severe osteolysis.
Authors: Grimaud E, Soubigou L, Couillaud S, Coipeau P, Moreau A, Passuti N, Gouin F, Redini F, Heymann D
Am. J. Pathol., 2003;163(5):2021-31.
Species: Human
Sample Type: Serum

A variant in the osteoprotegerin gene is associated with coronary atherosclerosis in patients with rheumatoid arthritis: results from a candidate gene study.
Authors: Chung C, Solus J, Oeser A, Li C, Raggi P, Smith J, Stein C
Int J Mol Sci, 0;16(2):3885-94.
Species: Human
Sample Type: Serum