Human FOLR3 DuoSet ELISA, 15 Plate (1 KT)
货号：
DY5319 基本售价：
10120.7 元 规格：
1 KIT
产品信息
概述| 货号 | DY5319 |
| 别名 | folate receptor 3 (gamma); Folate receptor 3; folate receptor gamma; FOLR3; FR-G; FR-gamma; gamma-hFR |
全称 | Folate Receptor 3 | | 反应种属 | Human |
| 目标/特异性 | Please see the product datasheet |
性能| 供应商 | R&D Systems |
| 检测类型 | Solid Phase Sandwich ELISA |
| Entrez Gene IDs | 2352 (Human); |
| 背景 | Folate receptor 3 (FOLR3), also known as folate receptor gamma, is a 32 kDa protein that binds folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. Mature FOLR3 is a glycosylated protein that contains an imperfect carboxy terminal GPI anchor sequence. A fraction of FOLR3 is GPI-linked to the cell surface, but the majority is released as a secreted protein. Mature human FOLR3 shares 74% and 83% amino acid (aa) sequence identity with FOLR1 and FOLR2, respectively. Orthologs of human FOLR3 have not been described in mouse or rat. A genetic polymorphism generates a truncated isoform that lacks the carboxy terminal 139 aa. FOLR3 is expressed by cells of the myelocyte and B lymphocyte lineage as well as by various carcinomas. FOLR3 is more highly expressed in ovarian carcinomas than in breast carcinomas or mesotheliomas. Unlike other folate receptors, FOLR3 does not exhibit stereoselectivity in the binding of folates. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
