| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. RAF inhibitors that evade paradoxical MAPK pathway activation.
Authors: Zhang C, Spevak W, Zhang Y, Burton E, Ma Y, Habets G, Zhang J, Lin J, Ewing T, Matusow B, Tsang G, Marimuthu A, Cho H, Wu G, Wang W, Fong D, Nguyen H, Shi S, Womack P, Nespi M, Shellooe R, Carias H, Powell B, Light E, Sanftner L, Walters J, Tsai J, West B, Visor G, Rezaei H, Lin P, Nolop K, Ibrahim P, Hirth P, Bollag G
Nature, 2015;526(7574):583-6.
Species: Mouse
Sample Type: Cell Culture Supernates
Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes.
Authors: Dreymueller D, Martin C, Schumacher J, Groth E, Boehm J, Reiss L, Uhlig S, Ludwig A
J Immunol, 2014;192(2):722-31.
Species: Human
Sample Type: Cell Culture Supernates
Anti-Tumour Effects of a Specific Anti-ADAM17 Antibody in an Ovarian Cancer Model In Vivo.
Authors: Richards FM, Tape CJ, Jodrell DI, Murphy G
PLoS ONE, 2012;7(7):e40597.
Species: Human
Sample Type: Tissue Homogenates
A disintegrin and metalloproteinase 17 (ADAM17) and epidermal growth factor receptor (EGFR) signaling drive the epithelial response to Staphylococcus aureus toxic shock syndrome toxin-1 (TSST-1).
Authors: Breshears L, Schlievert P, Peterson M
J Biol Chem, 2012;287(39):32578-87.
Species: Human
Sample Type: Cell Culture Supernates
LPA-producing enzyme PA-PLA(1)alpha regulates hair follicle development by modulating EGFR signalling.
Authors: Inoue A, Arima N, Ishiguro J, Prestwich GD, Arai H, Aoki J
EMBO J., 2011;30(20):4248-60.
Species: Mouse
Sample Type: Cell Culture Supernates
The EGFR ligands amphiregulin and heparin-binding egf-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer.
Authors: Yasumoto K, Yamada T, Kawashima A, Wang W, Li Q, Donev IS, Tacheuchi S, Mouri H, Yamashita K, Ohtsubo K, Yano S
Clin. Cancer Res., 2011;17(11):3619-30.
Species: Human
Sample Type: ascitic fluid from mice bearing human gastric cancer tumors
Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice.
Authors: Murthy A, Defamie V, Smookler DS
J. Clin. Invest., 2010;120(8):2731-44.
Species: Mouse
Sample Type: Cell Culture Supernates
Identification of biomarkers in human head and neck tumor cell lines that predict for in vitro sensitivity to gefitinib.
Authors: Hickinson DM, Marshall GB, Beran GJ
Clin Transl Sci, 2009;2(3):183-92.
Species: Human
Sample Type: Cell Lysates
Amphiregulin is much more abundantly expressed than transforming growth factor-alpha and epidermal growth factor in human follicular fluid obtained from patients undergoing in vitro fertilization-embryo transfer.
Authors: Inoue Y, Miyamoto S, Fukami T, Shirota K, Yotsumoto F, Kawarabayashi T
Fertil. Steril., 2009;91(4):1035-41.
Species: Human
Sample Type: Follicular Fluid
Expression and role of EGFR ligands induced in airway cells by PM2.5 and its components.
Authors: Rumelhard M, Ramgolam K, Hamel R, Marano F, Baeza-Squiban A
Eur. Respir. J., 2007;30(6):1064-73.
Species: Human
Sample Type: Cell Culture Supernates
Validation of HB-EGF and amphiregulin as targets for human cancer therapy.
Authors: Yotsumoto F, Yagi H, Suzuki SO, Oki E, Tsujioka H, Hachisuga T, Sonoda K, Kawarabayashi T, Mekada E, Miyamoto S
Biochem. Biophys. Res. Commun., 2007;365(3):555-61.
Species: Human
Sample Type: Cell Culture Supernates
Cigarette smoke synergistically enhances respiratory mucin induction by proinflammatory stimuli.
Authors: Baginski TK, Dabbagh K, Satjawatcharaphong C, Swinney DC
Am. J. Respir. Cell Mol. Biol., 2006;35(2):165-74.
Species: Human
Sample Type: Cell Culture Supernates
Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer.
Authors: Zhou BB, Peyton M, He B, Liu C, Girard L, Caudler E, Lo Y, Baribaud F, Mikami I, Reguart N, Yang G, Li Y, Yao W, Vaddi K, Gazdar AF, Friedman SM, Jablons DM, Newton RC, Fridman JS, Minna JD, Scherle PA
Cancer Cell, 2006;10(1):39-50.
Species: Human
Sample Type: Cell Culture Supernates
In-frame deletion in the EGF receptor alters kinase inhibition by gefitinib.
Authors: Sakai K, Yokote H, Murakami-Murofushi K, Tamura T, Saijo N, Nishio K
Biochem. J., 2006;397(3):537-43.
Species: Human
Sample Type: Cell Culture Supernates
Heparin-binding EGF-like growth factor is a promising target for ovarian cancer therapy.
Authors: Miyamoto S, Hirata M, Yamazaki A, Kageyama T, Hasuwa H, Mizushima H, Tanaka Y, Yagi H, Sonoda K, Kai M, Kanoh H, Nakano H, Mekada E
Cancer Res., 2004;64(16):5720-7.
Species: Human
Sample Type: Ascites
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