NG2 expression in microglial cells affects the expression of neurotrophic and proinflammatory factors by regulating FAK phosphorylation
Authors: Lie Zhu
Sci Rep, 2016;6(0):27983.
Species: Mouse
Sample Type: Serum

Age and lesion-induced increases of GDNF transgene expression in brain following intracerebral injections of DNA nanoparticles.
Authors: Yurek D, Hasselrot U, Cass W, Sesenoglu-Laird O, Padegimas L, Cooper M
Neuroscience, 2015;284(0):500-12.
Species: Human
Sample Type: Tissue Homogenates

Transplantation of human adipose tissue-derived stem cells delays clinical onset and prolongs life span in ALS mouse model.
Authors: Kim, Kwang S, Lee, Hong J, An, Jin, Kim, Yun B, Ra, Jung Cha, Lim, Inja, Kim, Seung U
Cell Transplant, 2014;23(12):1585-97.
Species: Human
Sample Type: cell culture supernate

Repeated systemic administration of human adipose-derived stem cells attenuates overt diabetic nephropathy in rats.
Authors: Zhang L, Li K, Liu X, Li D, Luo C, Fu B, Cui S, Zhu F, Zhao R, Chen X
Stem Cells Dev, 2013;22(23):3074-86.
Species: Human
Sample Type: cell culture supernate

Non-viral gene therapy for GDNF production in RCS rat: the crucial role of the plasmid dose.
Gene Ther., 2012;19(9):886-98.
Species: Rat
Sample Type: Cell Culture Supernates

A Monoclonal Antibody-GDNF Fusion Protein Is Not Neuroprotective and Is Associated with Proliferative Pancreatic Lesions in Parkinsonian Monkeys.
Authors: Ohshima-Hosoyama S, Simmons HA, Goecks N
PLoS ONE, 2012;7(6):e39036.
Species: Primate - Macaca mulatta (Rhesus monkey)
Sample Type: Tissue Homogenates

Improvement in disability after alemtuzumab treatment of multiple sclerosis is associated with neuroprotective autoimmunity.
Authors: Jones JL, Anderson JM, Phuah CL, Fox EJ, Selmaj K, Margolin D, Lake SL, Palmer J, Thompson SJ, Wilkins A, Webber DJ, Compston DA, Coles AJ
Brain, 2010;133(0):2232-47.
Species: Human
Sample Type: Cell Culture Supernates

Pharmacokinetics and bioactivity of glial cell line-derived factor (GDNF) and neurturin (NTN) infused into the rat brain.
Authors: Hadaczek P, Johnston L, Forsayeth J, Bankiewicz KS
Neuropharmacology, 2010;58(7):1114-21.
Species: Rat
Sample Type: Tissue Homogenates

Lack of humoral immune response to the tetracycline (Tet) activator in rats injected intracranially with Tet-off rAAV vectors.
Authors: Han Y, Chang QA, Virag T
Gene Ther., 2010;17(5):616-25.
Species: Rat
Sample Type: Tissue Homogenates

Glial cell line-derived neurotrophic factor-secreting genetically modified human bone marrow-derived mesenchymal stem cells promote recovery in a rat model of Parkinsons disease.
Authors: Glavaski-Joksimovic A, Virag T, Mangatu TA
J. Neurosci. Res., 2010;88(12):2669-81.
Species: Human
Sample Type: Cell Culture Supernates

Effect of nigrostriatal damage induced by 6-hydroxydopamine on the expression of glial cell line-derived neurotrophic factor in the striatum of the rat.
Authors: Mertens B, Massie A, Michotte Y, Sarre S
Neuroscience, 2009;162(1):148-54.
Species: Rat
Sample Type: Tissue Homogenates

Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF.
Authors: Emborg ME, Moirano J, Raschke J, Bondarenko V, Zufferey R, Peng S, Ebert AD, Joers V, Roitberg B, Holden JE, Koprich J, Lipton J, Kordower JH, Aebischer P
Neurobiol. Dis., 2009;36(2):303-11.
Species: Primate - Macaca mulatta (Rhesus monkey)
Sample Type: Tissue Homogenates

Sustained intraspinal delivery of neurotrophic factor encapsulated in biodegradable nanoparticles following contusive spinal cord injury.
Authors: Wang YC, Wu YT, Huang HY, Lin HI, Lo LW, Tzeng SF, Yang CS
Biomaterials, 2008;29(34):4546-53.
Species: Human
Sample Type: recombinant GDNF

Direct muscle delivery of GDNF with human mesenchymal stem cells improves motor neuron survival and function in a rat model of familial ALS.
Authors: Suzuki M, McHugh J, Tork C, Shelley B, Hayes A, Bellantuono I, Aebischer P, Svendsen CN
Mol. Ther., 2008;16(12):2002-10.
Species: Human
Sample Type: Cell Culture Supernates

Transient striatal delivery of GDNF via encapsulated cells leads to sustained behavioral improvement in a bilateral model of Parkinson disease.
Authors: Sajadi A, Bensadoun JC, Schneider BL, Lo Bianco C, Aebischer P
Neurobiol. Dis., 2006;22(1):119-29.
Species: Human
Sample Type: Cell Culture Supernates

Neurotrophic factors in relapsing remitting and secondary progressive multiple sclerosis patients during interferon beta therapy.
Authors: Caggiula M, Batocchi AP, Frisullo G, Angelucci F, Patanella AK, Sancricca C, Nociti V, Tonali PA, Mirabella M
Clin. Immunol., 2005;118(1):77-82.
Species: Human
Sample Type: Cell Culture Supernates

Intracerebral transplantation of carotid body in rats with transient middle cerebral artery occlusion.
Authors: Yu G, Xu L, Hadman M, Hess DC, Borlongan CV
Brain Res., 2004;1015(1):50-6.
Species: Rat
Sample Type: Tissue Homogenates

Prolonged biologically active transgene expression driven by HSV LAP2 in brain in vivo.
Authors: Puskovic V, Wolfe D, Goss J, Huang S, Mata M, Glorioso JC, Fink DJ
Mol. Ther., 2004;10(1):67-75.
Species: Rat
Sample Type: Tissue Homogenates

AF5, a CNS cell line immortalized with an N-terminal fragment of SV40 large T: growth, differentiation, genetic stability, and gene expression.
Authors: Truckenmiller ME, Vawter MP, Zhang P, Conejero-Goldberg C, Dillon-Carter O, Morales N, Cheadle C, Becker KG, Freed WJ
Exp. Neurol., 2002;175(0):318.
Species: Rat
Sample Type: Cell Culture Supernates

Lentiviral vectors as a gene delivery system in the mouse midbrain: cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF.
Authors: Bensadoun JC, Deglon N, Tseng JL, Ridet JL, Zurn AD, Aebischer P
Exp. Neurol., 2000;164(1):15-24.
Species: Human
Sample Type: Tissue Homogenates