| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Biomarkers of Host Response Predict Primary End-Point Radiological Pneumonia in Tanzanian Children with Clinical Pneumonia: A Prospective Cohort Study.
Authors: Erdman L, DAcremont V, Hayford K, Rajwans N, Kilowoko M, Kyungu E, Hongoa P, Alamo L, Streiner D, Genton B, Kain K
PLoS ONE, 2015;10(9):e0137592.
Species: Human
Sample Type: Plasma
Highly invasive melanoma cells activate the vascular endothelium via an MMP-2/integrin alphavbeta5-induced secretion of VEGF-A.
Am. J. Pathol., 2012;181(2):693-705.
Species: Human
Sample Type: Cell Culture Supernates
Combinations of Host Biomarkers Predict Mortality among Ugandan Children with Severe Malaria: A Retrospective Case-Control Study.
Authors: Erdman LK, Dhabangi A, Musoke C, Conroy AL, Hawkes M, Higgins S, Rajwans N, Wolofsky KT, Streiner DL, Liles WC, Cserti-Gazdewich CM, Kain KC
PLoS ONE, 2011;6(2):e17440.
Species: Human
Sample Type: Plasma
High platelet reactivity is associated with myocardial infarction in premenopausal women: a population-based case-control study.
Authors: Snoep JD, Roest M, Barendrecht AD
J. Thromb. Haemost., 2010;8(5):906-13.
Species: Human
Sample Type: Plasma
Thrombocytopenia in early malaria is associated with GP1b shedding in absence of systemic platelet activation and consumptive coagulopathy.
Authors: de Mast Q, de Groot PG, van Heerde WL, Roestenberg M, van Velzen JF, Verbruggen B, Roest M, McCall M, Nieman AE, Westendorp J, Syafruddin D, Fijnheer R, van Dongen-Lases EC, Sauerwein RW, van der Ven AJ
Br. J. Haematol., 2010;151(5):495-503.
Species: Human
Sample Type: Plasma
Cardiovascular risk factors are reduced with a low dose of acarbose in obese patients with polycystic ovary syndrome.
Authors: Araujo Penna I, Canella PR, Vieira CS, Silva de Sa MF, dos Reis RM, Ferriani RA
Fertil. Steril., 2007;88(2):519-22.
Species: Human
Sample Type: Serum
Delay of acute intracellular pH recovery after acidosis decreases endothelial cell activation.
Authors: Huck V, Niemeyer A, Goerge T, Schnaeker EM, Ossig R, Rogge P, Schneider MF, Oberleithner H, Schneider SW
J. Cell. Physiol., 2007;211(2):399-409.
Species: Human
Sample Type: Cell Culture Supernates
Plasma cytokine and P-selectin levels in advanced malignancy: prognostic value and impact of low-molecular weight heparin administration.
Authors: Di Nisio M, Niers TM, Reitsma PH, Buller HR
Cancer, 2005;104(10):2275-81.
Species: Human
Sample Type: Plasma
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| 背景 | The Selectin family is comprised of three members, E-Selectin, L-Selectin, and P-Selectin. E-Selectin [endothelial leukocyte adhesion molecule-1 (ELAM-1), CD62E] is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. The human and rat proteins share approximately 67% amino acid sequence identity. The mouse and rat proteins share approximately 78% amino acid sequence identity. L-Selectin (Leukocyte Selectin, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L) is expressed constitutively on a wide variety of leukocytes. Two forms of L-Selectin have been reported, apparently arising as a result of post-translational modifications. Human and mouse L-Selectin share 76% amino acid sequence identity. Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P) is expressed by activated platelets and endothelial cells. The extracellular domains of human and mouse P-Selectin share approximately 73% amino acid sequence identity. |
