Human Phospho-VEGF R2/KDR DuoSet IC ELISA, 2 Plate (1 KT)【科瑞奥博】

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Human Phospho-VEGF R2/KDR DuoSet IC ELISA, 2 Plate (1 KT)

货号： DYC1766-2 基本售价： 5125.8 元规格： 1 KIT

产品信息

概述
货号	DYC1766-2
别名	CD309 antigen; CD309; EC 2.7.10; EC 2.7.10.1; Fetal liver kinase 1; fetal liver kinase-1; Flk1; Flk-1; FLK1tyrosine kinase growth factor receptor; KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); Kinase insert domain receptor; Protein-tyrosine kinase receptor flk-1; soluble VEGFR2; vascular endothelial growth factor receptor 2; VEGF R2; VEGFR; VEGFR2; VEGFR-2
全称	Vascular Endothelial Growth Factor Receptor 2
反应种属	Human
目标/特异性	Please see the product datasheet

性能
供应商	R&D Systems
检测类型	Solid Phase Sandwich ELISA
Entrez Gene IDs	3791 (Human); 16542 (Mouse);
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Biomarkers for antitumor activity of bevacizumab in gastric cancer models. Authors: Yamashita-Kashima Y, Fujimoto-Ouchi K, Yorozu K, Kurasawa M, Yanagisawa M, Yasuno H, Mori K BMC Cancer, 2012;12(0):37. Species: Human Sample Type: Cell Lysates AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family. Authors: Gavine PR, Mooney L, Kilgour E Cancer Res., 2012;72(8):2045-56. Species: Human Sample Type: Cell Lysate The 12th-14th type III repeats of fibronectin function as a highly promiscuous growth factor-binding domain. Authors: Martino MM, Hubbell JA FASEB J., 2010;24(12):4711-21. Species: Human Sample Type: Cell Lysates Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3. Authors: Xu Y, Yuan L, Mak J, Pardanaud L, Caunt M, Kasman I, Larrivee B, Del Toro R, Suchting S, Medvinsky A, Silva J, Yang J, Thomas JL, Koch AW, Alitalo K, Eichmann A, Bagri A J. Cell Biol., 2010;188(1):115-30. Species: Human Sample Type: Cell Lysates Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting. Authors: Pan Q, Chathery Y, Wu Y, Rathore N, Tong RK, Peale F, Bagri A, Tessier-Lavigne M, Koch AW, Watts RJ J. Biol. Chem., 2007;282(33):24049-56. Species: Human Sample Type: Cell Lysates Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration. Authors: Favier B, Alam A, Barron P, Bonnin J, Laboudie P, Fons P, Mandron M, Herault JP, Neufeld G, Savi P, Herbert JM, Bono F Blood, 2006;108(4):1243-50. Species: Human Sample Type: Cell Lysates
背景	VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
运输条件	Blue Ice
存放说明	4℃