Mouse R-Spondin 3 DuoSet ELISA, 5 Plate (1 KT)
货号:
DY4120-05 基本售价:
4667.7 元 规格:
1 KIT
产品信息
概述货号 | DY4120-05 |
别名 | Cristin 1; CRISTIN1; FLJ14440; hPWTSR; hRspo3; Protein with TSP type-1 repeat; PWTSR; Roof plate-specific spondin-3; RSPO3; R-spondin 3 homolog (Xenopus laevis); RSpondin 3; R-Spondin 3; R-spondin-3; Thrombospondin type-1 domain-containing protein 2; thrombospondin, type I, domain containing 2; THSD2 |
全称 | Roof Plate-specific Spondin 3 | 反应种属 | Mouse |
目标/特异性 | Please see the product datasheet |
性能供应商 | R&D Systems |
检测类型 | Solid Phase Sandwich ELISA |
Entrez Gene IDs | 84870 (Human); 72780 (Mouse); |
背景 | R-Spondin 3 (RSPO3; Cristin 1) is a secreted Wnt regulating protein that is critical for development of the placental labyrinthine layer. It is expressed in the roof plate, tail, somites, otic vesicles, cephalic mesoderm, truncus arteriosus, atrioventricular canal of the developing heart, and strongly but transiently in developing limbs. R-Spondins regulate Wnt/ beta -catenin by competing with the Wnt antagonist DKK-1 for binding to the Wnt co-receptors LRP-6 and Kremen, reducing their DKK-1-mediated internalization. Reports differ on whether R-Spondins bind LRP-6 directly. |
运输条件 | Blue Ice |
存放说明 | 4℃ |