Human Prostatic Acid Phosphatase/ACPP DuoSet ELISA, 5 Plate (1 KT)
货号：
DY6240-05 基本售价：
4667.7 元 规格：
1 KIT
产品信息
概述| 货号 | DY6240-05 |
| 别名 | acid phosphatase, prostate; ACP3; ACP-3; ACPP; EC 3.1.3.2; PAP; Prostatic Acid Phosphatase; prostatic acid phosphotase |
| 反应种属 | Human |
| 目标/特异性 | Please see the product datasheet |
性能| 供应商 | R&D Systems |
| 检测类型 | Solid Phase Sandwich ELISA |
| Entrez Gene IDs | 55 (Human); 563181 (Mouse); 56780 (Rat); |
| 背景 | ACPP (Acid phosphatase, prostate; also PAP and ACP3) is a 48-52 kDa glycoprotein member of the histidine acid phosphatase family of enzymes. It exists as a 95-100 kDa nondisulfide-linked homodimer that hydrolyzes phosphate esters under low pH to generate free phosphate. ACPP is expressed by prostate epithelium and pain-detecting spinal cord neurons. In the spinal cord, ACPP dephosphorylates AMP. This generates adenosine which acts as a strong analgesic agent. Mature human ACPP is 354 amino acids (aa) in length (aa 33-386). It contains one histidine phosphatase domain (aa 34-332), plus a nucleophile acceptor site at His44, and a proton donor site at Asp290. There are two potential alternative splice variants. One shows a deletion of aa 153-185, while another is transmembrane (previously called TMPase) and shows a 38 aa substitution for the C-terminal seven amino acids. Over aa 33-379, human ACPP shares 84% aa identity with mouse ACPP. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
