R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Tumor-induced pressure in the bone microenvironment causes osteocytes to promote the growth of prostate cancer bone metastases. Authors: Sottnik J, Dai J, Zhang H, Campbell B, Keller E Cancer Res, 2015;75(11):2151-8. Species: Mouse Sample Type: Cell Culture Supernates
Ethanolic Echinacea purpurea Extracts Contain a Mixture of Cytokine-Suppressive and Cytokine-Inducing Compounds, Including Some That Originate from Endophytic Bacteria. Authors: Todd D, Gulledge T, Britton E, Oberhofer M, Leyte-Lugo M, Moody A, Shymanovich T, Grubbs L, Juzumaite M, Graf T, Oberlies N, Faeth S, Laster S, Cech N PLoS ONE, 2015;10(5):e0124276. Species: Mouse Sample Type: Cell culture supernatant
Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection. Authors: Brown A, Murphy A, Lalor S, Leech J, OKeeffe K, Mac Aogain M, OHalloran D, Lacey K, Tavakol M, Hearnden C, Fitzgerald-Hughes D, Humphreys H, Fennell J, van Wamel W, Foster T, Geoghegan J, Lavelle E, Rogers T, McLoughlin R PLoS Pathog, 2015;11(11):e1005226. Species: Mouse Sample Type: Cell Culture Supernates
Dietary galacto-oligosaccharides prevent airway eosinophilia and hyperresponsiveness in a murine house dust mite-induced asthma model. Authors: Verheijden K, Willemsen L, Braber S, Leusink-Muis T, Delsing D, Garssen J, Kraneveld A, Folkerts G Respir Res, 2015;16(0):17. Species: Mouse Sample Type: Homogenized Tissue
Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production. Authors: Kearney C, Cullen S, Tynan G, Henry C, Clancy D, Lavelle E, Martin S Cell Death Differ, 2015;22(8):1313-27. Species: Mouse Sample Type: Cell Culture Supernates
Lack of platelet-activating factor receptor protects mice against diet-induced adipose inflammation and insulin-resistance despite fat pad expansion. Authors: Menezes-Garcia Z, Oliveira M, Lima R, Soriani F, Cisalpino D, Botion L, Teixeira M, Souza D, Ferreira A Obesity (Silver Spring), 2014;22(3):663-72. Species: Mouse Sample Type: Tissue Homogenates
Interleukin-15 modulates adipose tissue by altering mitochondrial mass and activity. Authors: Barra, Nicole G, Palanivel, Rengasam, Denou, Emmanuel, Chew, Marianne, Gillgrass, Amy, Walker, Tina D, Kong, Josh, Richards, Carl D, Jordana, Manel, Collins, Stephen, Trigatti, Bernardo, Holloway, Alison C, Raha, Sandeep, Steinberg, Gregory, Ashkar, Ali A PLoS ONE, 2014;9(12):e114799. Species: Mouse Sample Type: Cell Culture Supernates
Control of allergen-induced inflammation and hyperresponsiveness by the metalloproteinase ADAMTS-12. Authors: Paulissen G, El Hour M, Rocks N, Gueders M, Bureau F, Foidart J, Lopez-Otin C, Noel A, Cataldo D J Immunol, 2012;189(8):4135-43. Species: Mouse Sample Type: Tissue Homogenates
Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, Is crucial for murine asthma. Authors: Suzukawa M, Morita H, Nambu A, Arae K, Shimura E, Shibui A, Yamaguchi S, Suzukawa K, Nakanishi W, Oboki K, Kajiwara N, Ohno T, Ishii A, Korner H, Cua D, Suto H, Yoshimoto T, Iwakura Y, Yamasoba T, Ohta K, Sudo K, Saito H, Okumura K, Broide D, Matsumoto K, Nakae S J Immunol, 2012;189(7):3641-52. Species: Mouse Sample Type: BALF
The role of alveolar epithelial cells in initiating and shaping pulmonary immune responses: communication between innate and adaptive immune systems. Authors: Chuquimia OD, Petursdottir DH, Rahman MJ, Hartl K, Singh M, Fernandez C PLoS ONE, 2012;7(2):e32125. Species: Mouse Sample Type: Cell Culture Supernates
Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection. Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C Infect. Immun., 2012;80(1):100-9. Species: Mouse Sample Type: Serum
Exosomes isolated from mycobacteria-infected mice or cultured macrophages can recruit and activate immune cells in vitro and in vivo. Authors: Singh PP, Smith VL, Karakousis PC, Schorey JS J. Immunol., 2012;189(2):777-85. Species: Mouse Sample Type: Cell Culture Supernates
Chemokine binding protein M3 of murine gammaherpesvirus 68 modulates the host response to infection in a natural host. Authors: Hughes DJ, Kipar A, Leeming GH, Bennett E, Howarth D, Cummerson JA, Papoula-Pereira R, Flanagan BF, Sample JT, Stewart JP PLoS Pathog., 2011;7(3):e1001321. Species: Mouse Sample Type: Tissue Homogenates
Identification and functional characterization of novel phosphorylation sites in TAK1-binding protein (TAB) 1. Authors: Wolf A, Beuerlein K, Eckart C, Weiser H, Dickkopf B, Muller H, Sakurai H, Kracht M PLoS ONE, 2011;6(12):e29256. Species: Mouse Sample Type: Cell Culture Supernates
Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus. Authors: Walsh KB, Teijaro JR, Wilker PR Proc. Natl. Acad. Sci. U.S.A., 2011;108(29):12018-23. Species: Mouse Sample Type: BALF
Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection. Authors: Teijaro JR, Walsh KB, Cahalan S, Fremgen DM, Roberts E, Scott F, Martinborough E, Peach R, Oldstone MB, Rosen H Cell, 2011;146(6):980-91. Species: Mouse Sample Type: BALF
Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid. Authors: van Neerven S, Regen T, Wolf D, Nemes A, Johann S, Beyer C, Hanisch UK, Mey J J. Neurochem., 2010;114(5):1511-26. Species: Mouse Sample Type: Cell Culture Supernates
Chorionic gonadotropin alleviates thioglycollate-induced peritonitis by affecting macrophage function. Authors: Wan H, Coppens JM, van Helden-Meeuwsen CG, Leenen PJ, Van Rooijen N, Khan NA, Kiekens RC, Benner R, Versnel MA J. Leukoc. Biol., 2009;86(2):361-70. Species: Mouse Sample Type: Peritoneal Lavage
Central role of MyD88-dependent dendritic cell maturation and proinflammatory cytokine production to control Brucella abortus infection. Authors: Macedo GC, Magnani DM, Carvalho NB, Bruna-Romero O, Gazzinelli RT, Oliveira SC J. Immunol., 2008;180(2):1080-7. Species: Mouse Sample Type: Cell Culture Supernates
Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes. Authors: Chou SY, Weng JY, Lai HL, Liao F, Sun SH, Tu PH, Dickson DW, Chern Y J. Neurosci., 2008;28(13):3277-90.
IFN-gamma synergizes with LPS to induce nitric oxide biosynthesis through glycogen synthase kinase-3-inhibited IL-10. Authors: Lin CF, Tsai CC, Huang WC, Wang CY, Tseng HC, Wang Y, Kai JI, Wang SW, Cheng YL J. Cell. Biochem., 2008;105(3):746-55. Species: Mouse Sample Type: Cell Culture Supernates
Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia. Authors: Schell JB, Crane CA, Smith MF, Roberts MR J. Neuroimmunol., 2007;189(1):75-87. Species: Mouse Sample Type: Cell Culture Supernates
Mycobacterium tuberculosis antigens specifically modulate CCR2 and MCP-1/CCL2 on lymphoid cells from human pulmonary hilar lymph nodes. Authors: Arias MA, Jaramillo G, Lopez YP, Mejia N, Mejia C, Pantoja AE, Shattock RJ, Garcia LF, Griffin GE J. Immunol., 2007;179(12):8381-91. Species: Human Sample Type: Cell Culture Supernates
Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis. Authors: Hegde A, Zhang H, Moochhala SM, Bhatia M J. Leukoc. Biol., 2007;82(3):678-85. Species: Mouse Sample Type: Plasma
Lipoxin A4 stable analogs reduce allergic airway responses via mechanisms distinct from CysLT1 receptor antagonism. Authors: Levy BD, Lukacs NW, Berlin AA, Schmidt B, Guilford WJ, Serhan CN, Parkinson JF FASEB J., 2007;21(14):3877-84. Species: Mouse Sample Type: Tissue Homogenates
Suppressive effect of simvastatin on interferon-beta-induced expression of CC chemokine ligand 5 in microglia. Authors: Nakamichi K, Saiki M, Kitani H, Kuboyama Y, Morimoto K, Takayama-Ito M, Kurane I Neurosci. Lett., 2006;407(3):205-10. Species: Mouse Sample Type: Cell Culture Supernates
Interleukin-17 is a negative regulator of established allergic asthma. Authors: Schnyder-Candrian S, Togbe D, Couillin I, Mercier I, Brombacher F, Quesniaux V, Fossiez F, Ryffel B, Schnyder B J. Exp. Med., 2006;203(12):2715-25. Species: Mouse Sample Type: Cell Culture Supernates
Mucosal administration of CpG oligodeoxynucleotide elicits strong CC and CXC chemokine responses in the vagina and serves as a potent Th1-tilting adjuvant for recombinant gD2 protein vaccination against genital herpes. Authors: Tengvall S, Lundqvist A, Eisenberg RJ, Cohen GH, Harandi AM J. Virol., 2006;80(11):5283-91. Species: Mouse Sample Type: Tissue Homogenates
Specific engagement of TLR4 or TLR3 does not lead to IFN-beta-mediated innate signal amplification and STAT1 phosphorylation in resident murine alveolar macrophages. Authors: Punturieri A, Alviani RS, Polak T, Copper P, Sonstein J, Curtis JL J. Immunol., 2004;173(2):1033-42. Species: Mouse Sample Type: Cell Culture Supernates
MIP-1 gamma promotes receptor-activator-of-NF-kappa-B-ligand-induced osteoclast formation and survival. Authors: Okamatsu Y, Battaglino R, Spate U, Stashenko P J. Immunol., 2004;173(3):2084-90. Species: Mouse Sample Type: Whole Cells
Orally administered CpG oligodeoxynucleotide induces production of CXC and CC chemokines in the gastric mucosa and suppresses bacterial colonization in a mouse model of Helicobacter pylori infection. Authors: Raghavan S, Nystrom J, Fredriksson M, Holmgren J, Harandi AM Infect. Immun., 2003;71(12):7014-22. Species: Mouse Sample Type: Serum
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