Poly-N-acetyl glucosamine production by Staphylococcus epidermidis cells increases their in vivo pro-inflammatory effect
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Type: Peritoneal Exudates

Host Inflammatory Response to Mosquito Bites Enhances the Severity of Arbovirus Infection
Authors: Marieke Pingen
Immunity, 2016;44(6):1455-69.
Species: Mouse
Sample Type: Tissue Homogenates

Plasminogen activator inhibitor-1 stimulates macrophage activation through Toll-like Receptor-4
Authors: Kamlesh K Gupta
Biochem Biophys Res Commun, 2016;0(0):.
Species: Mouse
Sample Type: Whole Cells

C1P Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Preventing NF-?B Activation in Neutrophils
J Immunol, 2016;196(5):2319-26.
Species: Mouse
Sample Type: BALF

Mast cells play an important role in chlamydia pneumoniae lung infection by facilitating immune cell recruitment into the airway.
Authors: Chiba N, Shimada K, Chen S, Jones H, Alsabeh R, Slepenkin A, Peterson E, Crother T, Arditi M
J Immunol, 2015;194(8):3840-51.
Species: Mouse
Sample Type: BALF

A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis.
Authors: Bernard N, Finlay C, Tannahill G, Cassidy J, ONeill L, Mills K
Mucosal Immunol, 2015;8(5):982-92.
Species: Mouse
Sample Type: Tissue Homogenates

C1q Deficiency Promotes Pulmonary Vascular Inflammation and Enhances the Susceptibility of the Lung Endothelium to Injury.
Authors: Shah D, Romero F, Zhu Y, Duong M, Sun J, Walsh K, Summer R
J Biol Chem, 2015;290(49):29642-51.
Species: Mouse
Sample Type: BALF

C-Type Lectin Receptor MCL Facilitates Mincle Expression and Signaling through Complex Formation.
Authors: Miyake Y, Masatsugu O, Yamasaki S
J Immunol, 2015;194(11):5366-74.
Species: Mouse
Sample Type: Cell Culture Supernates

Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.
Authors: Kearney C, Cullen S, Tynan G, Henry C, Clancy D, Lavelle E, Martin S
Cell Death Differ, 2015;22(8):1313-27.
Species: Mouse
Sample Type: Cell Culture Supernates

The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory.
Authors: Yoshida K, Maekawa T, Zhu Y, Renard-Guillet C, Chatton B, Inoue K, Uchiyama T, Ishibashi K, Yamada T, Ohno N, Shirahige K, Okada-Hatakeyama M, Ishii S
Nat Immunol, 2015;16(10):1034-43.
Species: Mouse
Sample Type: Serum

Gene and protein expression in response to different growth temperatures and oxygen availability in Burkholderia thailandensis.
Authors: Peano C, Chiaramonte F, Motta S, Pietrelli A, Jaillon S, Rossi E, Consolandi C, Champion O, Michell S, Freddi L, Falciola L, Basilico F, Garlanda C, Mauri P, De Bellis G, Landini P
PLoS ONE, 2014;9(3):e93009.
Species: Mouse
Sample Type: Cell Culture Supernates

Signaling via tumor necrosis factor receptor 1 but not Toll-like receptor 2 contributes significantly to hydrosalpinx development following Chlamydia muridarum infection.
Authors: Dong X, Liu Y, Chang X, Lei L, Zhong G
Infect Immun, 2014;82(5):1833-9.
Species: Mouse
Sample Type: Cell Culture Supernates

The lung inflammation and skeletal muscle wasting induced by subchronic cigarette smoke exposure are not altered by a high-fat diet in mice.
Authors: Hansen, Michelle, Chen, Hui, Jones, Jessica, Langenbach, Shenna Y, Vlahos, Ross, Gualano, Rosa C, Morris, Margaret, Anderson, Gary P
PLoS ONE, 2013;8(11):e80471.
Species: Mouse
Sample Type: Tissue Homogenates

Myeloid cell sirtuin-1 expression does not alter host immune responses to Gram-negative endotoxemia or Gram-positive bacterial infection.
Authors: Crotty Alexander, Laura E, Marsh, Brenda J, Timmer, Anjuli M, Lin, Ann E, Zainabadi, Kayvan, Czopik, Agnieszk, Guarente, Leonard, Nizet, Victor
PLoS ONE, 2013;8(12):e84481.
Species: Mouse
Sample Type: Plasma

Milk fat globule-epidermal growth factor-factor 8 attenuates neutrophil infiltration in acute lung injury via modulation of CXCR2.
Authors: Aziz M, Matsuda A, Yang WL, Jacob A, Wang P
J. Immunol., 2012;189(1):393-402.
Species: Mouse
Sample Type: Tissue Homogenates

Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C
Infect. Immun., 2012;80(1):100-9.
Species: Mouse
Sample Type: Serum

The role of alveolar epithelial cells in initiating and shaping pulmonary immune responses: communication between innate and adaptive immune systems.
Authors: Chuquimia OD, Petursdottir DH, Rahman MJ, Hartl K, Singh M, Fernandez C
PLoS ONE, 2012;7(2):e32125.
Species: Mouse
Sample Type: Cell Culture Supernates

Fecal lipocalin 2, a sensitive and broadly dynamic non-invasive biomarker for intestinal inflammation.
Authors: Chassaing B, Srinivasan G, Delgado M, Young A, Gewirtz A, Vijay-Kumar M
PLoS ONE, 2012;7(9):e44328.
Species: Mouse
Sample Type: Serum

Altered regulation of Toll-like receptor responses impairs antibacterial immunity in the allergic lung.
Authors: Habibzay, M, Saldana, J I, Goulding, J, Lloyd, C M, Hussell, T
Mucosal Immunol, 2012;5(5):524-34.
Species: Mouse
Sample Type: BALF

Lung-targeted overexpression of the NF-kappaB member RelB inhibits cigarette smoke-induced inflammation.
Authors: McMillan DH, Baglole CJ, Thatcher TH, Maggirwar S, Sime PJ, Phipps RP
Am. J. Pathol., 2011;179(1):125-33.
Species: Mouse
Sample Type: BALF

Local delivery of GM-CSF protects mice from lethal pneumococcal pneumonia.
Authors: Steinwede K, Tempelhof O, Bolte K, Maus R, Bohling J, Ueberberg B, Langer F, Christman JW, Paton JC, Ask K, Maharaj S, Kolb M, Gauldie J, Welte T, Maus UA
J. Immunol., 2011;187(10):5346-56.
Species: Mouse
Sample Type: BALF

Recombinant human tissue factor pathway inhibitor exerts anticoagulant, anti-inflammatory and antimicrobial effects in murine pneumococcal pneumonia.
Authors: Van Den Boogaard FE, Brands X, Schultz MJ, Levi M, Roelofs JJ, Van t Veer C, van der Poll T
J. Thromb. Haemost., 2011;9(1):122-32.

The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa.
Authors: Moalli F, Paroni M, Veliz Rodriguez T, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S, Nebuloni M, Mantovani A, Bragonzi A, Garlanda C
J. Immunol., 2011;186(9):5425-34.
Species: Mouse
Sample Type: Tissue Homogenates

Phosphoinositide 3-kinase gamma plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice.
Authors: Russo RC, Garcia CC, Barcelos LS, Rachid MA, Guabiraba R, Roffe E, Souza AL, Sousa LP, Mirolo M, Doni A, Cassali GD, Pinho V, Locati M, Teixeira MM
J. Leukoc. Biol., 2011;89(2):269-82.
Species: Mouse
Sample Type: Tissue Homogenates

Leukocyte ADAM17 Regulates Acute Pulmonary Inflammation.
Authors: Arndt PG, Strahan B, Wang Y, Long C, Horiuchi K, Walcheck B
PLoS ONE, 2011;6(5):e19938.
Species: Mouse
Sample Type: BALF

Distinct roles of hepatocyte- and myeloid cell-derived IL-1 receptor antagonist during endotoxemia and sterile inflammation in mice.
Authors: Lamacchia C, Palmer G, Bischoff L, Rodriguez E, Talabot-Ayer D, Gabay C
J. Immunol., 2010;185(0):2516-24.
Species: Mouse
Sample Type: Serum

Impact of adiponectin deficiency on pulmonary responses to acute ozone exposure in mice.
Authors: Zhu M, Hug C, Kasahara DI
Am. J. Respir. Cell Mol. Biol., 2010;43(4):487-97.
Species: Mouse
Sample Type: BALF

Ligands of the receptor for advanced glycation end products, including high-mobility group box 1, limit bacterial dissemination during Escherichia coli peritonitis.
Authors: van Zoelen MA, Achouiti A, Schmidt AM, Yang H, Florquin S, Tracey KJ, van der Poll T
Crit. Care Med., 2010;38(6):1414-22.
Species: Mouse
Sample Type: Peritoneal Fluid

Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid.
Authors: van Neerven S, Regen T, Wolf D, Nemes A, Johann S, Beyer C, Hanisch UK, Mey J
J. Neurochem., 2010;114(5):1511-26.
Species: Mouse
Sample Type: Cell Culture Supernates

Spatiotemporal expression of chemokines and chemokine receptors in experimental anti-myeloperoxidase antibody-mediated glomerulonephritis.
Authors: van der Veen BS, Petersen AH, Belperio JA, Satchell SC, Mathieson PW, Molema G, Heeringa P
Clin. Exp. Immunol., 2009;158(1):143-53.
Species: Mouse
Sample Type: Tissue Homogenates

Role of endothelial TLR4 for neutrophil recruitment into central nervous system microvessels in systemic inflammation.
Authors: Zhou H, Andonegui G, Wong CH, Kubes P
J. Immunol., 2009;183(8):5244-50.
Species: Mouse
Sample Type: Plasma

TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia.
Authors: Lagler H, Sharif O, Haslinger I, Matt U, Stich K, Furtner T, Doninger B, Schmid K, Gattringer R, de Vos AF, Knapp S
J. Immunol., 2009;183(3):2027-36.
Species: Mouse
Sample Type: Tissue Homogenates

Expression of inflammatory mediators in the otitis media induced by Helicobacter pylori antigen in mice.
Authors: Kariya S, Okano M, Fukushima K, Nomiya S, Kataoka Y, Nomiya R, Akagi H, Nishizaki K
Clin. Exp. Immunol., 2008;154(1):134-40.
Species: Mouse
Sample Type: middle ear wash

Surfactant protein D alters allergic lung responses in mice and human subjects.
Authors: Brandt EB, Mingler MK, Stevenson MD, Wang N, Khurana Hershey GK, Whitsett JA, Rothenberg ME
J. Allergy Clin. Immunol., 2008;121(5):1140-1147.e2.
Species: Mouse
Sample Type: BALF

Scavenging roles of chemokine receptors: chemokine receptor deficiency is associated with increased levels of ligand in circulation and tissues.
Authors: Cardona AE, Sasse ME, Liu L, Cardona SM, Mizutani M, Savarin C, Hu T, Ransohoff RM
Blood, 2008;112(2):256-63.
Species: Mouse
Sample Type: Tissue Homogenates

Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia.
Authors: Lembo A, Pelletier M, Iyer R, Timko M, Dudda JC, West TE, Wilson CB, Hajjar AM, Skerrett SJ
J. Immunol., 2008;180(11):7574-81.
Species: Mouse
Sample Type: Tissue Homogenates

The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature.
Authors: Coelho FM, Pinho V, Amaral FA, Sachs D, Costa VV, Rodrigues DH, Vieira AT, Silva TA, Souza DG, Bertini R, Teixeira AL, Teixeira MM
Arthritis Rheum., 2008;58(8):2329-37.
Species: Mouse
Sample Type: Tissue Homogenates

Neurokinin A engages neurokinin-1 receptor to induce NF-kappaB-dependent gene expression in murine macrophages: implications of ERK1/2 and PI 3-kinase/Akt pathways.
Authors: Sun J, Ramnath RD, Tamizhselvi R, Bhatia M
Am. J. Physiol., Cell Physiol., 2008;295(3):C679-91.
Species: Mouse
Sample Type: Cell Culture Supernates

An age-associated increase in pulmonary inflammation after burn injury is abrogated by CXCR2 inhibition.
Authors: Nomellini V, Faunce DE, Gomez CR, Kovacs EJ
J. Leukoc. Biol., 2008;83(6):1493-501.

Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
Immunity, 2007;26(4):445-59.
Species: Mouse
Sample Type: Cell Culture Supernates

Role of mesothelial cell-derived granulocyte colony-stimulating factor in interleukin-17-induced neutrophil accumulation in the peritoneum.
Authors: Witowski J, Ksiazek K, Warnecke C, Kuzlan M, Korybalska K, Tayama H, Wisniewska-Elnur J, Pawlaczyk K, Trominska J, Breborowicz A, Jorres A
Kidney Int., 2007;71(6):514-25.
Species: Mouse
Sample Type: Peritoneal Lavage

Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis.
Authors: Hegde A, Zhang H, Moochhala SM, Bhatia M
J. Leukoc. Biol., 2007;82(3):678-85.
Species: Mouse
Sample Type: Plasma

Dual effect of AMD3100, a CXCR4 antagonist, on bleomycin-induced lung inflammation.
Authors: Watanabe M, Matsuyama W, Shirahama Y, Mitsuyama H, Oonakahara K, Noma S, Higashimoto I, Osame M, Arimura K
J. Immunol., 2007;178(9):5888-98.
Species: Mouse
Sample Type: Tissue Homogenates

Role of Toll-like receptor 2 in recognition of Legionella pneumophila in a murine pneumonia model.
Authors: Fuse ET, Tateda K, Kikuchi Y, Matsumoto T, Gondaira F, Azuma A, Kudoh S, Standiford TJ, Yamaguchi K
J. Med. Microbiol., 2007;56(0):305-12.
Species: Mouse
Sample Type: Tissue Homogenates

Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infection.
Authors: Cheng W, Shivshankar P, Li Z, Chen L, Yeh IT, Zhong G
Infect. Immun., 2007;76(2):515-22.
Species: Mouse
Sample Type: Cell Culture Supernates

Minocycline modulates neuroinflammation independently of its antimicrobial activity in staphylococcus aureus-induced brain abscess.
Authors: Kielian T, Esen N, Liu S, Phulwani NK, Syed MM, Phillips N, Nishina K, Cheung AL, Schwartzman JD, Ruhe JJ
Am. J. Pathol., 2007;171(4):1199-214.
Species: Mouse
Sample Type: Cell Culture Supernates

Involvement of vitronectin in lipopolysaccaride-induced acute lung injury.
Authors: Tsuruta Y, Park YJ, Siegal GP, Liu G, Abraham E
J. Immunol., 2007;179(10):7079-86.
Species: Mouse
Sample Type: Tissue Homogenates

Effects of dexamethazone on LPS-induced activationand migration of mouse dendritic cells revealed by a genome-wide transcriptional analysis.
Authors: Vizzardelli C, Pavelka N, Luchini A, Zanoni I, Bendickson L, Pelizzola M, Beretta O, Foti M, Granucci F, Nilsen-Hamilton M, Ricciardi-Castagnoli P
Eur. J. Immunol., 2006;36(6):1504-15.
Species: Mouse
Sample Type: Cell Culture Supernates

Differential involvement of TLR2 and TLR4 in host survival during pulmonary infection with Chlamydia pneumoniae.
Authors: Rodriguez N, Wantia N, Fend F, Durr S, Wagner H, Miethke T
Eur. J. Immunol., 2006;36(5):1145-55.
Species: Mouse
Sample Type: Tissue Homogenates

Mucosal administration of CpG oligodeoxynucleotide elicits strong CC and CXC chemokine responses in the vagina and serves as a potent Th1-tilting adjuvant for recombinant gD2 protein vaccination against genital herpes.
Authors: Tengvall S, Lundqvist A, Eisenberg RJ, Cohen GH, Harandi AM
J. Virol., 2006;80(11):5283-91.
Species: Mouse
Sample Type: Tissue Homogenates

Increased pulmonary responses to acute ozone exposure in obese db/db mice.
Authors: Lu FL, Johnston RA, Flynt L, Theman TA, Terry RD, Schwartzman IN, Lee A, Shore SA
Am. J. Physiol. Lung Cell Mol. Physiol., 2006;290(5):L856-65.
Species: Mouse
Sample Type: Serum

TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.
Authors: Higgins SC, Jarnicki AG, Lavelle EC, Mills KH
J. Immunol., 2006;177(11):7980-9.
Species: Mouse
Sample Type: Tissue Homogenates

The pulmonary and hepatic immune microenvironment and its contribution to the early systemic inflammation following blunt chest trauma.
Authors: Perl M, Gebhard F, Braumuller S, Tauchmann B, Bruckner UB, Kinzl L, Knoferl MW
Crit. Care Med., 2006;34(4):1152-9.
Species: Mouse
Sample Type: BALF

Toll-like receptor 4 signaling leads to neutrophil migration impairment in polymicrobial sepsis.
Authors: Alves-Filho JC, de Freitas A, Russo M, Cunha FQ
Crit. Care Med., 2006;34(2):461-70.
Species: Mouse
Sample Type: Tissue Homogenates

Pyocyanin production by Pseudomonas aeruginosa induces neutrophil apoptosis and impairs neutrophil-mediated host defenses in vivo.
Authors: Allen L, Dockrell DH, Pattery T, Lee DG, Cornelis P, Hellewell PG, Whyte MK
J. Immunol., 2005;174(6):3643-9.
Species: Mouse
Sample Type: BALF

Tissue inhibitor of metalloproteinase-1 deficiency amplifies acute lung injury in bleomycin-exposed mice.
Authors: Kim KH, Burkhart K, Chen P, Frevert CW, Randolph-Habecker J, Hackman RC, Soloway PD, Madtes DK
Am. J. Respir. Cell Mol. Biol., 2005;33(3):271-9.
Species: Mouse
Sample Type: BALF

An essential role for non-bone marrow-derived cells in control of Pseudomonas aeruginosa pneumonia.
Authors: Hajjar AM, Harowicz H, Liggitt HD, Fink PJ, Wilson CB, Skerrett SJ
Am. J. Respir. Cell Mol. Biol., 2005;33(5):470-5.
Species: Mouse
Sample Type: Tissue Homogenates

Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus.
Authors: Esen N, Tanga FY, DeLeo JA, Kielian T
J. Neurochem., 2004;88(3):746-58.
Species: Mouse
Sample Type: Cell Culture Supernates