Eriobotrya japonica Water Extract Characterization: An Inducer of Interferon-Gamma Production Mainly by the JAK-STAT Pathway
Authors: Khalid Z Matalka
Molecules, 2016;21(6):.
Species: Mouse
Sample Type: Cell Culture Supernates

Poly-N-acetyl glucosamine production by Staphylococcus epidermidis cells increases their in vivo pro-inflammatory effect
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Type: Peritoneal Exudates

Proinflammatory M1 macrophages inhibit RANKL-induced osteoclastogenesis
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Type: Cell Culture Supernates

Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection.
Authors: Brown A, Murphy A, Lalor S, Leech J, OKeeffe K, Mac Aogain M, OHalloran D, Lacey K, Tavakol M, Hearnden C, Fitzgerald-Hughes D, Humphreys H, Fennell J, van Wamel W, Foster T, Geoghegan J, Lavelle E, Rogers T, McLoughlin R
PLoS Pathog, 2015;11(11):e1005226.
Species: Mouse
Sample Type: Cell Culture Supernates

Consistent inhibition of cyclooxygenase drives macrophages towards the inflammatory phenotype.
Authors: Na Y, Yoon Y, Son D, Jung D, Gu G, Seok S
PLoS ONE, 2015;10(2):e0118203.
Species: Mouse
Sample Type: Cell Culture Supernates

IL-10 Production in Macrophages Is Regulated by a TLR-Driven CREB-Mediated Mechanism That Is Linked to Genes Involved in Cell Metabolism.
Authors: Sanin D, Prendergast C, Mountford A
J Immunol, 2015;195(3):1218-32.
Species: Mouse
Sample Type: Cell Culture Supernates

Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM.
Authors: Assi H, Espinosa J, Suprise S, Sofroniew M, Doherty R, Zamler D, Lowenstein P, Castro M
PLoS ONE, 2014;9(5):e96318.
Species: Mouse
Sample Type: Cell Culture Supernates

Role of the aryl hydrocarbon receptor in the immune response profile and development of pathology during Plasmodium berghei Anka infection.
Authors: Brant F, Miranda A, Esper L, Rodrigues D, Kangussu L, Bonaventura D, Soriani F, Pinho V, Souza D, Rachid M, Weiss L, Tanowitz H, Teixeira M, Teixeira A, Machado F
Infect Immun, 2014;82(8):3127-40.
Species: Mouse
Sample Type: Tissue Homogenates

Role of OGR1 in myeloid-derived cells in prostate cancer.
Authors: Yan, L, Singh, L S, Zhang, L, Xu, Y
Oncogene, 2014;33(2):157-64.
Species: Mouse
Sample Type: Cell Culture Supernates

Effects of Lactobacillus kefiranofaciens M1 isolated from kefir grains on germ-free mice.
Authors: Chen Y, Chen M
PLoS ONE, 2013;8(11):e78789.
Species: Mouse
Sample Type: Cell Culture Supernates

Nod1 and Nod2 enhance TLR-mediated invariant NKT cell activation during bacterial infection.
Authors: Selvanantham T, Escalante N, Cruz Tleugabulova M, Fieve S, Girardin S, Philpott D, Mallevaey T
J Immunol, 2013;191(11):5646-54.
Species: Mouse
Sample Type: Cell Culture Supernates

Intravenous mesenchymal stem cells prevented rejection of allogeneic corneal transplants by aborting the early inflammatory response.
Authors: Oh J, Lee R, Yu J, Ko J, Lee H, Ko A, Roddy G, Prockop D
Mol Ther, 2012;20(11):2143-52.
Species: Mouse
Sample Type: Tissue Homogenates

OX40 ligand and programmed cell death 1 ligand 2 expression on inflammatory dendritic cells regulates CD4 T cell cytokine production in the lung during viral disease.
Authors: Wythe SE, Dodd JS, Openshaw PJ, Schwarze J
J. Immunol., 2012;188(4):1647-55.
Species: Mouse
Sample Type: BALF

Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C
Infect. Immun., 2012;80(1):100-9.
Species: Mouse
Sample Type: Serum

Intestinal epithelial cell-derived semaphorin 7A negatively regulates development of colitis via alphavbeta1 integrin.
Authors: Kang S, Okuno T, Takegahara N, Takamatsu H, Nojima S, Kimura T, Yoshida Y, Ito D, Ohmae S, You DJ, Toyofuku T, Jang MH, Kumanogoh A
J. Immunol., 2011;188(3):1108-16.
Species: Mouse
Sample Type: Cell Culture Supernates

Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity.
Authors: Sellge G, Magalhaes JG, Konradt C, Fritz JH, Salgado-Pabon W, Eberl G, Bandeira A, Di Santo JP, Sansonetti PJ, Phalipon A
J. Immunol., 2010;184(4):2076-85.
Species: Mouse
Sample Type: Cell Culture Supernates

A critical role for C5L2 in the pathogenesis of experimental allergic asthma.
Authors: Zhang X, Schmudde I, Laumonnier Y, Pandey MK, Clark JR, Konig P, Gerard NP, Gerard C, Wills-Karp M, Kohl J
J. Immunol., 2010;185(11):6741-52.
Species: Mouse
Sample Type: Cell Culture Supernates

Critical role of the IFN-stimulated gene factor 3 complex in TLR-mediated IL-27p28 gene expression revealing a two-step activation process.
Authors: Molle C, Goldman M, Goriely S
J. Immunol., 2010;184(4):1784-92.
Species: Mouse
Sample Type: Cell Culture Supernates

The IFN regulatory factor 7-dependent type I IFN response is not essential for early resistance against murine cytomegalovirus infection.
Authors: Steinberg C, Eisenacher K, Gross O, Reindl W, Schmitz F, Ruland J, Krug A
Eur. J. Immunol., 2009;39(4):1007-18.
Species: Mouse
Sample Type: Serum

Expression of bioactive single-chain murine IL-12 in transgenic plants.
Authors: Liu J, Dolan MC, Reidy M, Cramer CL
J. Interferon Cytokine Res., 2009;28(0):381-92.
Species: Mouse
Sample Type: Cell Culture Supernates

E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection.
Authors: Aronoff DM, Lewis C, Serezani CH, Eaton KA, Goel D, Phipps JC, Peters-Golden M, Mancuso P
J. Immunol., 2009;183(4):2642-9.
Species: Mouse
Sample Type: Tissue Homogenates

A conjugated linoleic acid-enriched beef diet attenuates lipopolysaccharide-induced inflammation in mice in part through PPARgamma-mediated suppression of toll-like receptor 4.
Authors: Reynolds CM, Draper E, Keogh B, Rahman A, Moloney AP, Mills KH, Loscher CE, Roche HM
J. Nutr., 2009;139(12):2351-7.
Species: Mouse
Sample Type: Cell Culture Supernates

Direct B cell stimulation by dendritic cells in a mouse model of lupus.
Authors: Wan S, Zhou Z, Duan B, Morel L
Arthritis Rheum., 2008;8(0):1741-50.
Species: Mouse
Sample Type: Cell Culture Supernates

CD40L-expressing CD8 T cells prime CD8alpha(+) DC for IL-12p70 production.
Authors: Wong KL, Lew FC, MacAry PA, Kemeny DM
Eur. J. Immunol., 2008;38(8):2251-62.
Species: Mouse
Sample Type: Cell Culture Supernates

Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia.
Authors: Lembo A, Pelletier M, Iyer R, Timko M, Dudda JC, West TE, Wilson CB, Hajjar AM, Skerrett SJ
J. Immunol., 2008;180(11):7574-81.
Species: Mouse
Sample Type: Tissue Homogenates

Immunotherapy for neuroblastoma using syngeneic fibroblasts transfected with IL-2 and IL-12.
Authors: Barker SE, Grosse SM, Siapati EK, Kritz A, Kinnon C, Thrasher AJ, Hart SL
Br. J. Cancer, 2007;97(2):210-7.
Species: Mouse
Sample Type: Cell Culture Supernates

Lung dendritic cells elicited by Fms-like tyrosine 3-kinase ligand amplify the lung inflammatory response to lipopolysaccharide.
Authors: von Wulffen W, Steinmueller M, Herold S, Marsh LM, Bulau P, Seeger W, Welte T, Lohmeyer J, Maus UA
Am. J. Respir. Crit. Care Med., 2007;176(9):892-901.
Species: Mouse
Sample Type: BALF

Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
Immunity, 2007;26(4):445-59.
Species: Mouse
Sample Type: Cell Culture Supernates

Mycobacterium tuberculosis antigens specifically modulate CCR2 and MCP-1/CCL2 on lymphoid cells from human pulmonary hilar lymph nodes.
Authors: Arias MA, Jaramillo G, Lopez YP, Mejia N, Mejia C, Pantoja AE, Shattock RJ, Garcia LF, Griffin GE
J. Immunol., 2007;179(12):8381-91.
Species: Human
Sample Type: Cell Culture Supernates

Role of Toll-like receptor 2 in recognition of Legionella pneumophila in a murine pneumonia model.
Authors: Fuse ET, Tateda K, Kikuchi Y, Matsumoto T, Gondaira F, Azuma A, Kudoh S, Standiford TJ, Yamaguchi K
J. Med. Microbiol., 2007;56(0):305-12.
Species: Mouse
Sample Type: Tissue Homogenates

Glucose-6-phosphate dehydrogenase deficiency and the inflammatory response to endotoxin and polymicrobial sepsis.
Authors: Wilmanski J, Villanueva E, Deitch EA, Spolarics Z
Crit. Care Med., 2007;35(2):510-8.
Species: Mouse
Sample Type: Plasma

Lactoferrin enhanced efficacy of the BCG vaccine to generate host protective responses against challenge with virulent Mycobacterium tuberculosis.
Authors: Hwang SA, Wilk KM, Budnicka M, Olsen M, Bangale YA, Hunter RL, Kruzel ML, Actor JK
Vaccine, 2007;25(37):6730-43.
Species: Mouse
Sample Type: Cell Culture Supernates

Leukemia inhibitory factor is linked to regulatory transplantation tolerance.
Authors: Metcalfe SM, Watson TJ, Shurey S, Adams E, Green CJ
Transplantation, 2005;79(6):726-30.
Species: Mouse
Sample Type: Cell Culture Supernates

Immunosuppressive effects of CCL17 on pulmonary antifungal responses during pulmonary invasive aspergillosis.
Authors: Carpenter KJ, Hogaboam CM
Infect. Immun., 2005;73(11):7198-207.
Species: Mouse
Sample Type: Tissue Homogenates

Cytokine production in association with phagocytosis of apoptotic cells by immature dendritic cells.
Authors: Takahashi M, Kobayashi Y
Cell. Immunol., 2003;226(2):105-15.
Species: Mouse
Sample Type: Cell Culture Supernates

Intracellular thiols contribute to Th2 function via a positive role in IL-4 production.
Authors: Monick MM, Samavati L, Butler NS, Mohning M, Powers LS, Yarovinsky T, Spitz DR, Hunninghake GW
J. Immunol., 2003;171(10):5107-15.
Species: Mouse
Sample Type: Cell Culture Supernates

Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody.
Authors: O'Garra A
J. Exp. Med., 2002;196(4):541-9.
Species: Mouse
Sample Type: Cell Culture Supernates

Interleukin 12 (IL-12), also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. The IL-12 p40 subunit is shared by IL-23, another heterodimeric cytokine that has biological activities similar to, as well as distinct from, IL-12. IL-12 is produced by macrophages and B cells and has been shown to have multiple effects on T cells and natural killer (NK) cells. While mouse IL-12 is active on both human and mouse cells, human IL-12 is not active on mouse cells.