Mouse GM-CSF DuoSet ELISA, 5 Plate (1 KT)【科瑞奥博】

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Mouse GM-CSF DuoSet ELISA, 5 Plate (1 KT)

货号： DY415-05 基本售价： 3882.5 元规格： 1 KIT

产品信息

概述
货号	DY415-05
别名	colony stimulating factor 2 (granulocyte-macrophage); Colony-stimulating factor; CSF; CSF2; GMCSF; GM-CSF; GMCSFgranulocyte-macrophage colony-stimulating factor; granulocyte-macrophage colony stimulating factor; MGC131935; MGC138897; molgramostin; sargramostim
全称	Granulocyte Macrophage Growth Factor
反应种属	Mouse
目标/特异性	Please see the product datasheet

性能
供应商	R&D Systems
检测类型	Solid Phase Sandwich ELISA
Entrez Gene IDs	1437 (Human); 12981 (Mouse); 116630 (Rat); 397208 (Porcine); 403923 (Canine); 493805 (Feline);
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood Authors: K Klocke, S Sakaguchi, R Holmdahl, K Wing Proc Natl Acad Sci USA, 2016;0(0):. Species: Mouse Sample Type: Cell Culture Supernates ER? in CD4+ T Cells Is Crucial for Ligand-Mediated Suppression of Central Nervous System Autoimmunity J Immunol, 2016;0(0):. Species: Mouse Sample Type: Cell Culture Supernates Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy. Authors: Kim J, Li W, Choi Y, Lewin S, Verbeke C, Dranoff G, Mooney D Nat Biotechnol, 2015;33(1):64-72. Species: Mouse Sample Type: mesoporous silica rods Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection. Authors: Zhao Y, Olonisakin T, Xiong Z, Hulver M, Sayeed S, Yu M, Gregory A, Kochman E, Chen B, Mallampalli R, Sun M, Silverstein R, Stolz D, Shapiro S, Ray A, Ray P, Lee J Mucosal Immunol, 2015;8(4):896-905. Species: Mouse Sample Type: Tissue Homogenates Macrophage Dectin-1 Expression Is Controlled by Leukotriene B4 via a GM-CSF/PU.1 Axis. Authors: Serezani CH, Kane S, Collins L J. Immunol., 2012;189(2):906-15. Species: Mouse Sample Type: BALF The role of alveolar epithelial cells in initiating and shaping pulmonary immune responses: communication between innate and adaptive immune systems. Authors: Chuquimia OD, Petursdottir DH, Rahman MJ, Hartl K, Singh M, Fernandez C PLoS ONE, 2012;7(2):e32125. Species: Mouse Sample Type: Cell Culture Supernates The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. Authors: El-Behi M, Ciric B, Dai H Nat. Immunol., 2011;12(6):568-75. Species: Mouse Sample Type: Cell Culture Supernates Local delivery of GM-CSF protects mice from lethal pneumococcal pneumonia. Authors: Steinwede K, Tempelhof O, Bolte K, Maus R, Bohling J, Ueberberg B, Langer F, Christman JW, Paton JC, Ask K, Maharaj S, Kolb M, Gauldie J, Welte T, Maus UA J. Immunol., 2011;187(10):5346-56. Species: Mouse Sample Type: BALF IL-33-responsive lineage- CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs. Authors: Bartemes KR, Iijima K, Kobayashi T, Kephart GM, McKenzie AN, Kita H J. Immunol., 2011;188(3):1503-13. Species: Mouse Sample Type: Cell Culture Supernates A synthetic analog of alpha-galactosylceramide induces macrophage activation via the TLR4-signaling pathways. Authors: Hung LC, Lin CC, Hung SK, Wu BC, Jan MD, Liou SH, Fu SL Biochem. Pharmacol., 2007;73(12):1957-70. Species: Mouse Sample Type: Cell Culture Supernates The p110delta catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion. Authors: Kim N, Saudemont A, Webb L, Camps M, Ruckle T, Hirsch E, Turner M, Colucci F Blood, 2007;110(9):3202-8. Species: Mouse Sample Type: Cell Culture Supernates
背景	GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor) induces the development of monocytes, neutrophils, eosinophils, and myeloid and dermal dendritic cells. It also acts as a neutrophil and dendritic cell chemoattractant. GM-CSF promotes Th1 and Th17 cell mediated autoimmune inflammation as well as the inflammatory activation of dendritic cells, microglia, alveolar macrophages, and eosinophils. In addition, it cooperates with G-CSF in promoting tumor cell proliferation and invasion. GM-CSF signals through a receptor complex composed of GM-CSF R alpha and the Common beta Chain (beta c) with Syndecan-2 as a potential co-receptor. The beta c subunit is shared by the receptor complexes for IL-3 and IL-5.
运输条件	Blue Ice
存放说明	4℃