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Mouse IL-2 DuoSet ELISA, 5 Plate (1 KT)

货号: DY402-05 基本售价: 3882.5 元 规格: 1 KIT

产品信息

概述
货号DY402-05
别名
aldesleukin; IL2; IL-2; IL-2lymphokine; interleukin 2; interleukin-2; involved in regulation of T-cell clonal expansion; T cell growth factor; T-cell growth factor; TCGF
全称Interleukin 2
反应种属Mouse
目标/特异性Please see the product datasheet
性能
供应商R&D Systems
检测类型Solid Phase Sandwich ELISA
Entrez Gene IDs3558 (Human); 16183 (Mouse); 116562 (Rat); 396868 (Porcine); 280822 (Bovine); 403989 (Canine); 100034204 (Equine); 751114 (Feline); 100302458 (Rabbit);
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Dendritic Cell-Like Cells Accumulate in Regenerating Murine Skeletal Muscle after Injury and Boost Adaptive Immune Responses Only upon a Microbial Challenge
PLoS ONE, 2016;11(5):e0155870.
Species: Mouse
Sample Type: Cell Culture Supernates

Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis
PLoS ONE, 2016;11(5):e0154630.
Species: Mouse
Sample Type: Cell Culture Supernates

Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate Signaling.
Authors: Wu Y, Wu Y, Mo S, Hsiao H, He Y, Lai M
J Immunol, 2015;195(6):2612-23.
Species: Mouse
Sample Type: Cell Culture Supernates

TAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse.
Authors: Na B, Kim H, Piragyte I, Oh H, Kwon M, Akber U, Lee H, Park D, Song W, Park Z, Im S, Rho M, Hyun Y, Kim M, Jun C
J Cell Biol, 2015;209(1):143-62.
Species: Mouse
Sample Type: Cell Culture Supernates

Role of OGR1 in myeloid-derived cells in prostate cancer.
Authors: Yan, L, Singh, L S, Zhang, L, Xu, Y
Oncogene, 2014;33(2):157-64.
Species: Mouse
Sample Type: Cell Culture Supernates

Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C
Infect. Immun., 2012;80(1):100-9.
Species: Mouse
Sample Type: Serum

Api6/AIM/Sp{alpha}/CD5L Overexpression in Alveolar Type II Epithelial Cells Induces Spontaneous Lung Adenocarcinoma.
Authors: Li Y, Qu P, Wu L, Li B, Du H, Yan C
Cancer Res., 2011;71(16):5488-99.
Species: Mouse
Sample Type: Serum

CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1.
Authors: Han Y, Guo Q, Zhang M, Chen Z, Cao X
J. Immunol., 2009;182(1):111-20.
Species: Mouse
Sample Type: Cell Culture Supernates

Mucosal immunity in mice induced by orally administered transgenic rice.
Authors: Zhang X, Yuan Z, Duan Q, Zhu H, Yu H, Wang Q
Vaccine, 2009;27(10):1596-600.
Species: Mouse
Sample Type: Cell Culture Supernates

Adenosine A2A receptor activation inhibits T helper 1 and T helper 2 cell development and effector function.
Authors: Csoka B, Himer L, Selmeczy Z, Vizi ES, Pacher P, Ledent C, Deitch EA, Spolarics Z, Nemeth ZH, Hasko G
FASEB J., 2008;22(10):3491-9.
Species: Mouse
Sample Type: Cell Culture Supernates

Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis.
Authors: Kaya Z, Goser S, Buss SJ, Leuschner F, Ottl R, Li J, Volkers M, Zittrich S, Pfitzer G, Rose NR, Katus HA
Circulation, 2008;118(20):2063-72.
Species: Mouse
Sample Type: Cell Culture Supernates

Effect of intestinal microbiota on the induction of regulatory CD25+ CD4+ T cells.
Authors: Ishikawa H, Tanaka K, Maeda Y, Aiba Y, Hata A, Tsuji NM, Koga Y, Matsumoto T
Clin. Exp. Immunol., 2008;153(1):127-35.
Species: Mouse
Sample Type: Cell Culture Supernates

Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation.
Authors: Lages CS, Suffia I, Velilla PA, Huang B, Warshaw G, Hildeman DA, Belkaid Y, Chougnet C
J. Immunol., 2008;181(3):1835-48.
Species: Mouse
Sample Type: Cell Culture Supernates

Amelioration of delayed-type hypersensitivity responses by IL-27 administration.
Authors: Miyazaki Y, Shimanoe Y, Wang S, Yoshida H
Biochem. Biophys. Res. Commun., 2008;373(3):397-402.
Species: Mouse
Sample Type: Cell Culture Supernates

Streptococcus equi antigens adsorbed onto surface modified poly-epsilon-caprolactone microspheres induce humoral and cellular specific immune responses.
Authors: Florindo HF, Pandit S, Goncalves LM, Alpar HO, Almeida AJ
Vaccine, 2008;26(33):4168-77.
Species: Mouse
Sample Type: Cell Culture Supernates

Differing effects of clarithromycin and azithromycin on cytokine production by murine dendritic cells.
Authors: Sugiyama K, Shirai R, Mukae H, Ishimoto H, Nagata T, Sakamoto N, Ishii H, Nakayama S, Yanagihara K, Mizuta Y, Kohno S
Clin. Exp. Immunol., 2007;147(3):540-6.
Species: Mouse
Sample Type: Cell Culture Supernates

Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
Immunity, 2007;26(4):445-59.
Species: Mouse
Sample Type: Cell Culture Supernates

An alternative pathway of NF-kappaB activation results in maturation and T cell priming activity of dendritic cells overexpressing a mutated IkappaBalpha.
Authors: Moore F, Buonocore S, Aksoy E, Ouled-Haddou N, Goriely S, Lazarova E, Paulart F, Heirman C, Vaeremans E, Thielemans K, Goldman M, Flamand V
J. Immunol., 2007;178(3):1301-11.
Species: Mouse
Sample Type: Cell Culture Supernates

Lactoferrin enhanced efficacy of the BCG vaccine to generate host protective responses against challenge with virulent Mycobacterium tuberculosis.
Authors: Hwang SA, Wilk KM, Budnicka M, Olsen M, Bangale YA, Hunter RL, Kruzel ML, Actor JK
Vaccine, 2007;25(37):6730-43.
Species: Mouse
Sample Type: Cell Culture Supernates

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells.
Authors: Fitzgerald DC, Zhang GX, El-Behi M, Fonseca-Kelly Z, Li H, Yu S, Saris CJ, Gran B, Ciric B, Rostami A
Nat. Immunol., 2007;8(12):1372-9.
Species: Mouse
Sample Type: Cell Culture Supernates

CD8+ T cells are not required for vaccine-induced immunity against Leishmania amazonensis in IL-12/23P40(-/-) C57BL/6 mice.
Authors: Hernandez Sanabria MX, Afonso LC, Golgher D, Tafuri WL, Vieira LQ
Microbes Infect., 2007;9(9):1124-34.
Species: Mouse
Sample Type: Cell Culture Supernates

The related adaptors, adaptor in lymphocytes of unknown function X and Rlk/Itk-binding protein, have nonredundant functions in lymphocytes.
Authors: Perchonock CE, Pajerowski AG, Nguyen C, Shapiro MJ, Shapiro VS
J. Immunol., 2007;179(3):1768-75.
Species: Mouse
Sample Type: Cell Culture Supernates

Osteopontin regulates hindlimb-unloading-induced lymphoid organ atrophy and weight loss by modulating corticosteroid production.
Authors: Wang KX, Shi Y, Denhardt DT
Proc. Natl. Acad. Sci. U.S.A., 2007;104(37):14777-82.
Species: Mouse
Sample Type: Cell Culture Supernates

CD40L disruption enhances Abeta vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation.
Authors: Obregon D, Hou H, Bai Y, Nikolic WV, Mori T, Luo D, Zeng J, Ehrhart J, Fernandez F, Morgan D, Giunta B, Town T, Tan J
Neurobiol. Dis., 2007;29(2):336-53.
Species: Mouse
Sample Type: Cell Culture Supernates

Negative regulation of interleukin-2 and p38 mitogen-activated protein kinase during T-cell activation by the adaptor ALX.
Authors: Perchonock CE, Fernando MC, Quinn WJ, Nguyen CT, Sun J, Shapiro MJ, Shapiro VS
Mol. Cell. Biol., 2006;26(16):6005-15.
Species: Mouse
Sample Type: Cell Culture Supernates

Exogenous IL-12 suppresses experimental autoimmune encephalomyelitis (EAE) by tuning IL-10 and IL-5 levels in an IFN-gamma-dependent way.
Authors: Berghmans N, Dillen C, Heremans H
J. Neuroimmunol., 2006;176(1):63-75.
Species: Mouse
Sample Type: Cell Culture Supernates

Induction of CTLA-4-mediated anergy contributes to persistent colonization in the murine model of gastric Helicobacter pylori infection.
Authors: Anderson KM, Czinn SJ, Redline RW, Blanchard TG
J. Immunol., 2006;176(9):5306-13.
Species: Mouse
Sample Type: Cell Culture Supernates

Transgenic expression of a CD83-immunoglobulin fusion protein impairs the development of immune-competent CD4-positive T cells.
Authors: Luthje K, Cramer SO, Ehrlich S, Veit A, Steeg C, Fleischer B, Bonin A, Breloer M
Eur. J. Immunol., 2006;36(8):2035-45.
Species: Mouse
Sample Type: Cell Culture Supernates

Effects of dexamethazone on LPS-induced activationand migration of mouse dendritic cells revealed by a genome-wide transcriptional analysis.
Authors: Vizzardelli C, Pavelka N, Luchini A, Zanoni I, Bendickson L, Pelizzola M, Beretta O, Foti M, Granucci F, Nilsen-Hamilton M, Ricciardi-Castagnoli P
Eur. J. Immunol., 2006;36(6):1504-15.
Species: Mouse
Sample Type: Cell Culture Supernates

The effects of dehydroepiandrosterone (DHEA) on in vitro spleen cell proliferation and cytokine production.
Authors: Powell JM, Sonnenfeld G
J. Interferon Cytokine Res., 2006;26(1):34-9.
Species: Mouse
Sample Type: Cell Culture Supernates

Subcellular fractions of Brucella ovis distinctively induce the production of interleukin-2, interleukin-4, and interferon-gamma in mice.
Authors: Salas-Tellez E, Nunez del Arco A, Tenorio V, Diaz-Aparicio E, de la Garza M, Suarez-Guemes F
Can. J. Vet. Res., 2005;69(1):53-7.
Species: Mouse
Sample Type: Cell Culture Supernates

Leukemia inhibitory factor is linked to regulatory transplantation tolerance.
Authors: Metcalfe SM, Watson TJ, Shurey S, Adams E, Green CJ
Transplantation, 2005;79(6):726-30.
Species: Mouse
Sample Type: Cell Culture Supernates

Comparative immunomodulatory properties of a chitosan-MDP adjuvant combination following intranasal or intramuscular immunisation.
Authors: Moschos SA, Bramwell VW, Somavarapu S, Alpar HO
Vaccine, 2005;23(16):1923-30.
Species: Mouse
Sample Type: Cell Culture Supernates

Leukaemia inhibitory factor (LIF) is functionally linked to axotrophin and both LIF and axotrophin are linked to regulatory immune tolerance.
Authors: Metcalfe SM, Muthukumarana PA, Thompson HL, Haendel MA, Lyons GE
FEBS Lett., 2005;579(3):609-14.
Species: Human
Sample Type: Cell Culture Supernates

Active hexose correlated compound enhances the immune function of mice in the hindlimb-unloading model of spaceflight conditions.
Authors: Aviles H, Belay T, Vance M, Sun B, Sonnenfeld G
J. Appl. Physiol., 2004;97(4):1437-44.
Species: Mouse
Sample Type: Cell Culture Supernates

Comparison of immunogenicities of recombinant Plasmodium vivax merozoite surface protein 1 19- and 42-kiloDalton fragments expressed in Escherichia coli.
Authors: Sachdeva S, Ahmad G, Malhotra P, Mukherjee P, Chauhan VS
Infect. Immun., 2004;72(10):5775-82.
Species: Mouse
Sample Type: Cell Culture Supernates

Intracellular thiols contribute to Th2 function via a positive role in IL-4 production.
Authors: Monick MM, Samavati L, Butler NS, Mohning M, Powers LS, Yarovinsky T, Spitz DR, Hunninghake GW
J. Immunol., 2003;171(10):5107-15.
Species: Mouse
Sample Type: Cell Culture Supernates

Transcutaneous immunization with cholera toxin B subunit adjuvant suppresses IgE antibody responses via selective induction of Th1 immune responses.
Authors: Anjuere F, George-Chandy A, Audant F, Rousseau D, Holmgren J, Czerkinsky C
J. Immunol., 2003;170(3):1586-92.
Species: Mouse
Sample Type:

TARM1 Is a Novel Leukocyte Receptor Complex-Encoded ITAM Receptor That Costimulates Proinflammatory Cytokine Secretion by Macrophages and Neutrophils.
Authors: Radjabova V, Mastroeni P, Skjodt K, Zaccone P, de Bono B, Goodall J, Chilvers E, Juss J, Jones D, Trowsdale J, Barrow A
J Immunol, 0;195(7):3149-59.
Species: Mouse
Sample Type: Cell Culture Supernates

背景IL-2 (Interleukin 2) is a critical cytokine in T cell biology. It promotes T cell activation and expansion, the development, maintenance and function of regulatory T cells (Treg), and the differentiation of CD8+ T cells into terminal effector cells and memory cells. IL-2 signals through a receptor complex composed of CD25/IL-2 R alpha, IL-2 R beta, and the Common gamma Chain (gamma c). IL-2 R beta is also a component of the IL-15 receptor complex. Gamma c is also a signaling subunit in the receptors for IL-4, -7, -9, -15, and -21.
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