| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Modulation of Endothelial Inflammation by Low and High Magnitude Cyclic Stretch
PLoS ONE, 2016;11(4):e0153387.
Species: Human
Sample Type: Cell Culture Supernates
Inflammatory and Angiogenic Factors at Mid-Pregnancy Are Associated with Spontaneous Preterm Birth in a Cohort of Tanzanian Women.
Authors: McDonald C, Darling A, Conroy A, Tran V, Cabrera A, Liles W, Wang M, Aboud S, Urassa W, Fawzi W, Kain K
PLoS ONE, 2015;10(8):e0134619.
Species: Human
Sample Type: Plasma
Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.
Authors: Kearney C, Cullen S, Tynan G, Henry C, Clancy D, Lavelle E, Martin S
Cell Death Differ, 2015;22(8):1313-27.
Species: Human
Sample Type: Cell Culture Supernates
Benefits of whole body vibration training in patients hospitalised for COPD exacerbations - a randomized clinical trial.
Authors: Greulich T, Nell C, Koepke J, Fechtel J, Franke M, Schmeck B, Haid D, Apelt S, Filipovic S, Kenn K, Janciauskiene S, Vogelmeier C, Koczulla A
BMC Pulm Med, 2014;14(0):60.
Species: Human
Sample Type: Serum
Induction of pro-inflammatory response of the placental trophoblast by Plasmodium falciparum infected erythrocytes and TNF.
Authors: Vasquez A, Segura C, Blair S
Malar J, 2013;12(0):421.
Species: Human
Sample Type: Cell Culture Supernates
Combinations of Host Biomarkers Predict Mortality among Ugandan Children with Severe Malaria: A Retrospective Case-Control Study.
Authors: Erdman LK, Dhabangi A, Musoke C, Conroy AL, Hawkes M, Higgins S, Rajwans N, Wolofsky KT, Streiner DL, Liles WC, Cserti-Gazdewich CM, Kain KC
PLoS ONE, 2011;6(2):e17440.
Species: Human
Sample Type: Plasma
Endothelium-based biomarkers are associated with cerebral malaria in Malawian children: a retrospective case-control study.
Authors: Conroy AL, Phiri H, Hawkes M, Glover S, Mallewa M, Seydel KB, Taylor TE, Molyneux ME, Kain KC
PLoS ONE, 2010;5(12):e15291.
Species: Human
Sample Type: Plasma
The role of RGD-tagged helical rosette nanotubes in the induction of inflammation and apoptosis in human lung adenocarcinoma cells through the P38 MAPK pathway.
Authors: Suri SS, Rakotondradany F, Myles AJ, Fenniri H, Singh B
Biomaterials, 2009;30(17):3084-90.
Species: Human
Sample Type: Cell Culture Supernates
Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women.
Authors: Hawn TR, Scholes D, Wang H, Li SS, Stapleton AE, Janer M, Aderem A, Stamm WE, Zhao LP, Hooton TM
PLoS ONE, 2009;4(12):e8300.
Species: Human
Sample Type: Urine
Suspension microarrays for the identification of the response patterns in hyperinflammatory diseases.
Authors: Hsu HY, Wittemann S, Schneider EM, Weiss M, Joos TO
Med Eng Phys, 2008;30(8):976-83.
Species: Human
Sample Type: Plasma
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| 背景 | ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin, Fibrinogen, Hyaluronan, rhinoviruses, and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease, type 2 diabetes, organ transplant dysfunction, oxidant stress, increased abdominal fat mass, hypertension, liver disease, certain malignancies, and cerebral malaria. |
