Human CXCL12/SDF-1 DuoSet ELISA, 5 Plate (1 KT)【科瑞奥博】

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Human CXCL12/SDF-1 DuoSet ELISA, 5 Plate (1 KT)

货号： DY350-05 基本售价： 3882.5 元规格： 1 KIT

产品信息

概述
货号	DY350-05
别名	chemokine (C-X-C motif) ligand 12; C-X-C motif chemokine 12; CXCL12; hIRH; hSDF-1; Intercrine reduced in hepatomas; IRH; PBSF; PBSFSDF-1a; Pre-B cell growth-stimulating factor; SCYB12; SDF1; SDF-1; SDF1A; SDF1B; SDF1SDF-1b; stromal cell-derived factor 1; TLSF; TLSF-a; TLSF-b; TPAR1
反应种属	Human
目标/特异性	Please see the product datasheet

性能
供应商	R&D Systems
检测类型	Solid Phase Sandwich ELISA
Entrez Gene IDs	6387 (Human); 20315 (Mouse); 493806 (Feline); 574334 (Rhesus Macaque);
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. CXCR4 positive and angiogenic monocytes in myocardial infarction. Thromb Haemost, 2013;109(2):255-62. Species: Human Sample Type: Plasma Identification of a New Phenotype of Tolerogenic Human Dendritic Cells Induced by Fungal Proteases from Aspergillus oryzae. Authors: Zimmer A, Luce S, Gaignier F, Nony E, Naveau M, Biola-Vidamment A, Pallardy M, Van Overtvelt L, Mascarell L, Moingeon P J. Immunol., 2011;186(7):3966-76. Species: Human Sample Type: Cell Culture Supernates Distinct platelet packaging, release, and surface expression of proangiogenic and antiangiogenic factors on different platelet stimuli. Authors: Chatterjee M, Huang Z, Zhang W, Jiang L, Hultenby K, Zhu L, Hu H, Nilsson GP, Li N Blood, 2011;117(14):3907-11. Species: Human Sample Type: Cell Culture Supernates The EGFR ligands amphiregulin and heparin-binding egf-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer. Authors: Yasumoto K, Yamada T, Kawashima A, Wang W, Li Q, Donev IS, Tacheuchi S, Mouri H, Yamashita K, Ohtsubo K, Yano S Clin. Cancer Res., 2011;17(11):3619-30. Species: Human Sample Type: ascitic fluid from mice bearing human gastric cancer tumors CXCL12 is essential for migration of activated Langerhans cells from epidermis to dermis. Authors: Ouwehand K, Santegoets SJ, Bruynzeel DP, Scheper RJ, de Gruijl TD, Gibbs S Eur. J. Immunol., 2008;38(11):3050-9. Species: Human Sample Type: Cell Culture Supernates Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing. Authors: Jung Y, Wang J, Schneider A, Sun YX, Koh-Paige AJ, Osman NI, McCauley LK, Taichman RS Bone, 2006;38(4):497-508. Species: Human Sample Type: Cell Culture Supernates
背景	CXCL12/Stromal Cell-derived Factor 1 (SDF-1) is a member of the CXC chemokine ligand superfamily. Six alternatively spliced CXCL12/SDF-1 isoforms have been identified including, CXCL12/SDF-1 alpha, CXCL12/SDF-1 beta, and CXCL12/SDF-1 gamma. CXCL12/SDF-1 alpha is 89 amino acids (aa) in length with a predicted molecular weight of 10 kDa, CXCL12/SDF-1 beta is 93 aa in length with a predicted molecular weight of 10.6 kDa, and CXCL12/SDF-1 gamma is 119 aa in length with a predicted molecular weight of 13.7 kDa. The mouse CXCL12/SDF-1 orthologs share 99% aa sequence identity with the human protein. The alpha and beta isoforms are ubiquitously expressed while the gamma isoform is primarily expressed in the heart. CXCL12/SDF-1 isoforms are chemotactic for T lymphocytes and monocytes. It is cardio protective and has also been shown to hinder CXCR4-mediated HIV infection of T cells.
运输条件	Blue Ice
存放说明	4℃