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Human IL-17 DuoSet ELISA, 5 Plate (1 KT)

货号: DY317-05 基本售价: 3882.5 元 规格: 1 KIT

产品信息

概述
货号DY317-05
别名
CTLA-8; CTLA8cytotoxic T-lymphocyte-associated serine esterase 8; Cytotoxic T-lymphocyte-associated antigen 8; IL17; IL-17; IL17A; IL-17A; IL-17Acytotoxic T-lymphocyte-associated protein 8; IL-17CTLA-8; IL17interleukin-17A; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A
全称Interleukin 17
反应种属Human
目标/特异性Please see the product datasheet
性能
供应商R&D Systems
检测类型Solid Phase Sandwich ELISA
Entrez Gene IDs3605 (Human); 16171 (Mouse); 301289 (Rat); 481837 (Canine);
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion
Authors: Mélissa Noack
Arthritis Res Ther, 2016;18(0):148.
Species: Human
Sample Type: Cell Culture Supernates

Stromal fibroblasts support dendritic cells to maintain IL-23/Th17 responses after exposure to ionizing radiation
Authors: A Malecka, Q Wang, S Shah, RV Sutavani, I Spendlove, JM Ramage, J Greensmith, HA Franks, MJ Gough, A Saalbach, PM Patel, AM Jackson
J Leukoc Biol, 2016;0(0):.
Species: Human
Sample Type: Cell Culture Supernates

Analysis of receptor tyrosine kinase genetics identifies two novel risk loci in GAS6 and PROS1 in Beh�et's disease
Sci Rep, 2016;6(0):26662.
Species: Human
Sample Type: Cell Culture Supernates

Cytokine profiles at admission can be related to outcome in AIDS patients with cryptococcal meningitis.
Authors: Mora D, Fortunato L, Andrade-Silva L, Ferreira-Paim K, Rocha I, Vasconcelos R, Silva-Teixeira D, Nascentes G, Silva-Vergara M
PLoS ONE, 2015;10(3):e0120297.
Species: Human
Sample Type: Serum

Cooperation between IL-7 Receptor and Integrin alpha2beta1 (CD49b) Drives Th17-Mediated Bone Loss.
Authors: El Azreq M, Arseneault C, Boisvert M, Page N, Allaeys I, Poubelle P, Tessier P, Aoudjit F
J Immunol, 2015;195(9):4198-209.
Species: Human
Sample Type: Cell Culture Supernates

Interleukin-23 Receptor Gene Polymorphism May Enhance Expression of the IL-23 Receptor, IL-17, TNF-alpha and IL-6 in Behcet's Disease.
Authors: Jiang Z, Hennein L, Tao Y, Tao L
PLoS ONE, 2015;10(7):e0134632.
Species: Human
Sample Type: Cell Culture Supernates

HIF-1alpha- and hypoxia-dependent immune responses in human CD4+CD25high T cells and T helper 17 cells.
Authors: Bollinger T, Gies S, Naujoks J, Feldhoff L, Bollinger A, Solbach W, Rupp J
J Leukoc Biol, 2014;96(2):305-12.
Species: Human
Sample Type: Cell Culture Supernates

CD137 ligand signalling induces differentiation of primary acute myeloid leukaemia cells.
Authors: Cheng K, Wong S, Linn Y, Ho L, Chng W, Schwarz H
Br J Haematol, 2014;165(1):134-44.
Species: Human
Sample Type: Cell Culture Supernates

IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist.
Authors: van de Veerdonk FL, Stoeckman AK, Wu G, Boeckermann AN, Azam T, Netea MG, Joosten LA, Van der Meer JW, Hao R, Kalabokis V, Dinarello CA
Proc. Natl. Acad. Sci. U.S.A., 2012;109(8):3001-5.
Species: Human
Sample Type: Cell Culture Supernates

CCR2+CCR5+ T Cells Produce Matrix Metalloproteinase-9 and Osteopontin in the Pathogenesis of Multiple Sclerosis.
Authors: Sato W, Tomita A, Ichikawa D, Lin Y, Kishida H, Miyake S, Ogawa M, Okamoto T, Murata M, Kuroiwa Y, Aranami T, Yamamura T
J Immunol, 2012;189(10):5057-65.
Species: Human
Sample Type: Cell Culture Supernates

Elevated adaptive immune responses are associated with latent infections of Wuchereria bancrofti.
Authors: Arndts K, Deininger S, Specht S, Klarmann U, Mand S, Adjobimey T, Debrah AY, Batsa L, Kwarteng A, Epp C, Taylor M, Adjei O, Layland LE, Hoerauf A
PLoS Negl Trop Dis, 2012;6(4):e1611.
Species: Human
Sample Type: Cell Culture Supernates

IFN-alpha blocks IL-17 production by peripheral blood mononuclear cells in Behcet's disease.
Authors: Liu X, Yang P, Wang C, Li F, Kijlstra A
Rheumatology (Oxford), 2011;50(2):293-8.
Species: Human
Sample Type: Cell Culture Supernates

Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.
Authors: Jones GW, Stumhofer JS, Foster T, Twohig JP, Hertzog P, Topley N, Williams AS, Hunter CA, Jenkins BJ, Wang EC, Jones SA
FASEB J., 2011;25(1):409-19.
Species: Human
Sample Type: Cell Culture Supernates

Elevated serum osteopontin levels and genetic polymorphisms of osteopontin are associated with Vogt-Koyanagi-Harada disease.
Authors: Chu M, Yang P, Hu R, Hou S, Li F, Chen Y, Kijlstra A
Invest. Ophthalmol. Vis. Sci., 2011;52(10):7084-9.
Species: Human
Sample Type: Cell Culture Supernates

Up-regulation of platelet activation in hemophilia A.
Authors: van Bladel ER, Roest M
Haematologica, 2011;0(0):.
Species: Human
Sample Type: Plasma

Serum levels of Th17-related cytokines in Behcet disease patients after cataract surgery.
Authors: Jiang S, Liu X, Luo L, Qu B, Huang X, Lin Y, Ye S, Liu Y
Mol. Vis., 2011;17(0):1425-30.
Species: Human
Sample Type: Serum

A naturally occurring, soluble antagonist of human IL-23 inhibits the development and in vitro function of human Th17 cells.
Authors: Yu RY, Gallagher G
J. Immunol., 2010;185(12):7302-8.
Species: Human
Sample Type: Cell Culture Supernates

IL-27 mediates the response to IFN-beta therapy in multiple sclerosis patients by inhibiting Th17 cells.
Authors: Sweeney CM, Lonergan R, Basdeo SA, Kinsella K, Dungan LS, Higgins SC, Kelly PJ, Costelloe L, Tubridy N, Mills KH, Fletcher JM
Brain Behav. Immun., 2010;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Neut
TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23.
Authors: Aliahmadi E, Gramlich R, Grutzkau A, Hitzler M, Kruger M, Baumgrass R, Schreiner M, Wittig B, Wanner R, Peiser M
Eur. J. Immunol., 2009;39(5):1221-30.
Species: Human
Sample Type: Cell Culture Supernates

Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin.
Authors: Johansen C, Usher PA, Kjellerup RB
Br. J. Dermatol., 2009;160(2):319-24.
Species: Human
Sample Type: Tissue Homogenates

Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells.
Authors: Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G
Circulation, 2009;119(10):1424-32.
Species: Human
Sample Type: Plasma

Diminished frequency and function of CD4+CD25high regulatory T cells associated with active uveitis in Vogt-Koyanagi-Harada syndrome.
Authors: Chen L, Yang P, Zhou H, He H, Ren X, Chi W, Wang L, Kijlstra A
Invest. Ophthalmol. Vis. Sci., 2008;49(8):3475-82.
Species: Human
Sample Type: Cell Culture Supernates

Cutting edge: Human Th17 cells are identified as bearing CCR2+CCR5- phenotype.
Authors: Sato W, Aranami T, Yamamura T
J. Immunol., 2007;178(12):7525-9.
Species: Human
Sample Type: Cell Culture Supernates

Blockade of TLR9 agonist-induced type I interferons promotes inflammatory cytokine IFN-gamma and IL-17 secretion by activated human PBMC.
Authors: Meyers JA, Mangini AJ, Nagai T, Roff CF, Sehy D, van Seventer JM
Cytokine, 2006;35(5):235-46.
Species: Human
Sample Type: Cell Culture Supernates

IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate.
Authors: Miranda-Carus ME, Balsa A, Benito-Miguel M, Perez de Ayala C, Martin-Mola E
J. Immunol., 2004;173(2):1463-76.
Species: Human
Sample Type: Cell Culture Supernates

背景The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.
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