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Human CCL5/RANTES DuoSet ELISA, 5 Plate (1 KT)

货号: DY278-05 基本售价: 3882.5 元 规格: 1 KIT

产品信息

概述
货号DY278-05
别名
CCL5; chemokine (C-C motif) ligand 5; D17S136Enormally T-expressed, and presumably secreted; EoCP; Eosinophil chemotactic cytokine; RANTES; SISd; SIS-delta; small inducible cytokine A5 (RANTES); small inducible cytokine subfamily A (Cys-Cys), member 5; Small-inducible cytokine A5; T cell-specific protein P228; T-cell specific protein p288; TCP228T-cell-specific protein RANTES
反应种属Human
目标/特异性Please see the product datasheet
性能
供应商R&D Systems
检测类型Solid Phase Sandwich ELISA
Entrez Gene IDs6352 (Human); 20304 (Mouse); 403522 (Canine); 493689 (Feline);
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Unfractionated Heparin Selectively Modulates the Expression of CXCL8, CCL2 and CCL5 in Endometrial Carcinoma Cells
Authors: A Doster, U Schwarzig, M Zygmunt, J Rom, F Schütz, H Fluhr
Anticancer Res, 2016;36(4):1535-44.
Species: Human
Sample Type: Cell Culture Supernates

Experimental hyperglycemia induces an increase of monocyte and T-lymphocyte content in adipose tissue of healthy obese women.
Authors: Tencerova M, Kracmerova J, Krauzova E, Malisova L, Kovacova Z, Wedellova Z, Siklova M, Stich V, Rossmeislova L
PLoS ONE, 2015;10(3):e0122872.
Species: Human
Sample Type: Plasma

Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.
Authors: Kearney C, Cullen S, Tynan G, Henry C, Clancy D, Lavelle E, Martin S
Cell Death Differ, 2015;22(8):1313-27.
Species: Human
Sample Type: Cell Culture Supernates

Role of hydrogen sulfide in paramyxovirus infections.
Authors: Li H, Ma Y, Escaffre O, Ivanciuc T, Komaravelli N, Kelley J, Coletta C, Szabo C, Rockx B, Garofalo R, Casola A
J Virol, 2015;89(10):5557-68.
Species: Human
Sample Type: cell supernates

Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction.
Authors: Projahn D, Simsekyilmaz S, Singh S, Kanzler I, Kramp B, Langer M, Burlacu A, Bernhagen J, Klee D, Zernecke A, Hackeng T, Groll J, Weber C, Liehn E, Koenen R
J Cell Mol Med, 2014;18(5):790-800.
Species: Human
Sample Type: cell supernates

Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays.
Authors: Shen K, Luk S, Hicks D, Elman J, Bohr S, Iwamoto Y, Murray R, Pena K, Wang F, Seker E, Weissleder R, Yarmush M, Toner M, Sgroi D, Parekkadan B
Nat Commun, 2014;5(0):5662.
Species: Human
Sample Type: cell culture supernate

Human cytomegalovirus induces a biphasic inflammatory response in primary endothelial cells.
Authors: Jeffery H, Soderberg-Naucler C, Butler L
J Virol, 2013;87(11):6530-5.
Species: Human
Sample Type: cell culture supernate

Measles virus causes immunogenic cell death in human melanoma.
Authors: Donnelly, O G, Errington-Mais, F, Steele, L, Hadac, E, Jennings, V, Scott, K, Peach, H, Phillips, R M, Bond, J, Pandha, H, Harrington, K, Vile, R, Russell, S, Selby, P, Melcher, A A
Gene Ther, 2013;20(1):7-15.
Species: Human
Sample Type: cell culture supernate

IRF5 promotes inflammatory macrophage polarization and T(H)1-T(H)17 responses.
Authors: Krausgruber T, Blazek K, Smallie T
Nat. Immunol., 2011;12(3):231-8.
Species: Human
Sample Type: Cell Culture Supernates

A role for the human nucleotide-binding domain, leucine-rich repeat-containing family member NLRC5 in antiviral responses.
Authors: Neerincx A, Lautz K, Menning M, Kremmer E, Zigrino P, Hosel M, Buning H, Schwarzenbacher R, Kufer TA
J. Biol. Chem., 2010;285(34):26223-32.
Species: Human
Sample Type: Cell Culture Supernates

IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes.
Authors: Pennino D, Eyerich K, Scarponi C, Carbone T, Eyerich S, Nasorri F, Garcovich S, Traidl-Hoffmann C, Albanesi C, Cavani A
J. Immunol., 2010;184(9):4880-8.
Species: Human
Sample Type: Cell Culture Supernates

Thrombocytopenia in early malaria is associated with GP1b shedding in absence of systemic platelet activation and consumptive coagulopathy.
Authors: de Mast Q, de Groot PG, van Heerde WL, Roestenberg M, van Velzen JF, Verbruggen B, Roest M, McCall M, Nieman AE, Westendorp J, Syafruddin D, Fijnheer R, van Dongen-Lases EC, Sauerwein RW, van der Ven AJ
Br. J. Haematol., 2010;151(5):495-503.
Species: Human
Sample Type: Plasma

Novel markers of inflammation identified in tumor necrosis factor receptor-associated periodic syndrome (TRAPS) by transcriptomic analysis of effects of TRAPS-associated tumor necrosis factor receptor type I mutations in an endothelial cell line.
Authors: Rebelo SL, Amel-Kashipaz MR, Radford PM, Bainbridge SE, Fiets R, Fang J, McDermott EM, Powell RJ, Todd I, Tighe PJ
Arthritis Rheum., 2009;60(1):269-80.
Species: Human
Sample Type: Cell Culture Supernates

Altered levels of CC chemokines during pulmonary CMV predict BOS and mortality post-lung transplantation.
Authors: Weigt SS, Elashoff RM, Keane MP, Strieter RM, Gomperts BN, Xue YY, Ardehali A, Gregson AL, Kubak B, Fishbein MC, Saggar R, Ross DJ, Lynch JP, Zisman DA, Belperio JA
Am. J. Transplant., 2008;8(7):1512-22.
Species: Human
Sample Type: BALF

Vitamin D and glucocorticoids differentially modulate chemokine expression in human airway smooth muscle cells.
Authors: Banerjee A, Damera G, Bhandare R, Gu S, Lopez-Boado Y, Panettieri R, Tliba O
Br. J. Pharmacol., 2008;155(1):84-92.
Species: Human
Sample Type: Cell Culture Supernates

Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes.
Authors: Chou SY, Weng JY, Lai HL, Liao F, Sun SH, Tu PH, Dickson DW, Chern Y
J. Neurosci., 2008;28(13):3277-90.
Species: Human
Sample Type: Cell Culture Supernates

CD8 chemokine receptors in chronic obstructive pulmonary disease.
Authors: Smyth LJ, Starkey C, Gordon FS, Vestbo J, Singh D
Clin. Exp. Immunol., 2008;154(1):56-63.
Species: Human
Sample Type: BALF

Preadipocyte response and impairment of differentiation in an inflammatory environment.
Authors: Poulain-Godefroy O, Froguel P
Biochem. Biophys. Res. Commun., 2007;356(3):662-7.
Species: Human
Sample Type: Cell Culture Supernates

PAPP-A and osteoprotegerin, together with interleukin-8 and RANTES, are elevated in the peritoneal fluid of women with endometriosis.
Authors: Bersinger NA, von Roten S, Wunder DM, Raio L, Dreher E, Mueller MD
Am. J. Obstet. Gynecol., 2006;195(1):103-8.
Species: Human
Sample Type: Peritoneal Fluid

The cytokine IL-1beta activates IFN response factor 3 in human fetal astrocytes in culture.
Authors: Rivieccio MA, John GR, Song X, Suh HS, Zhao Y, Lee SC, Brosnan CF
J. Immunol., 2005;174(6):3719-26.
Species: Human
Sample Type: Cell Culture Supernates

Manipulation of host cytokine network by ticks: a potential gateway for pathogen transmission.
Authors: Hajnicka V, Vancova I, Kocakova P, Slovak M, Gasperik J, Slavikova M, Hails RS, Labuda M, Nuttall PA
Parasitology, 2005;130(0):333-42.
Species: Human
Sample Type: Saliva

Chemokine secretion of rheumatoid arthritis synovial fibroblasts stimulated by Toll-like receptor 2 ligands.
Authors: Pierer M, Rethage J, Seibl R, Lauener R, Brentano F, Wagner U, Hantzschel H, Michel BA, Gay RE, Gay S, Kyburz D
J. Immunol., 2004;172(2):1256-65.
Species: Human
Sample Type: Cell Culture Supernates

Virally stimulated plasmacytoid dendritic cells produce chemokines and induce migration of T and NK cells.
Authors: Megjugorac NJ, Young HA, Amrute SB, Olshalsky SL, Fitzgerald-Bocarsly P
J. Leukoc. Biol., 2004;75(3):504-14.
Species: Human
Sample Type: Cell Culture Supernates

Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments.
Authors: Oynebraten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G
Blood, 2004;104(2):314-20.
Species: Human
Sample Type: Cell Culture Supernates

Involvement of Fc gamma RI (CD64) in the mechanism of HIV-1 inhibition by polyclonal IgG purified from infected patients in cultured monocyte-derived macrophages.
Authors: Holl V, Hemmerter S, Burrer R, Schmidt S, Bohbot A, Aubertin AM, Moog C
J. Immunol., 2004;173(10):6274-83.
Species: Human
Sample Type: Cell Culture Supernates

Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS.
Authors: Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle MT, Pedemonte E, Noonan D, Albini A, Bernardi G, Mancardi GL, Battistini L, Uccelli A
J. Leukoc. Biol., 2003;73(5):584-90.
Species: Human
Sample Type: CSF

Differential production of RANTES and MCP-1 in synovial fluid from the inflamed human knee.
Authors: Conti P, Reale M, Barbacane RC, Castellani ML, Orso C
Immunol. Lett., 2002;80(2):105-11.
Species: Human
Sample Type: Serum

背景CCL5/RANTES is a secreted beta-chemokine that plays a primary role in the inflammatory immune response through chemoattraction and activation of leukocytes that express CCR1, 3, 4, or 5. The two N-terminal residues of CCL5 can be removed by CD26/DPPIV, generating a protein that functions as a chemotaxis inhibitor. The deposition of CCL5 on activated vascular endothelial cells is crucial for monocyte adhesion to damaged vasculature. CCL5 is upregulated in breast cancer and promotes tumor progression through the attraction of proinflammatory macrophages in addition to its actions on tumor cells, stromal cells, and the vasculature. In humans, CCR5 binding to CCL5 inhibits the infectivity of R5 (M-tropic) but not X4 (T-tropic) strains of HIV-1.
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