R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells. Authors: Saulep-Easton D, Vincent F, Quah P, Wei A, Ting S, Croce C, Tam C, Mackay F Leukemia, 2016;30(1):163-72. Species: Human Sample Type: Cell Culture Supernates
Acanthamoeba castellanii (Genotype T4) Stimulates the Production of Interleukin-10 as well as Pro-inflammatory Cytokines in THP-1 Cells, Human Peripheral Blood Mononuclear Cells and Human Monocyte-Derived Macrophages Infect Immun, 2016;0(0):. Species: Human Sample Type: Cell Culture Supernates
Soluble alpha-enolase activates monocytes by CD14-dependent TLR4 signalling pathway and exhibits a dual function Authors: C Guillou, M Fréret, E Fondard, C Derambure, G Avenel, ML Golinski, M Verdet, O Boyer, F Caillot, P Musette, T Lequerré, O Vittecoq Sci Rep, 2016;6(0):23796. Species: Human Sample Type: Cell Culture Supernates
Genetic polymorphisms of cell adhesion molecules in Behcet's disease in a Chinese Han population Authors: M Zheng, L Zhang, H Yu, J Hu, Q Cao, G Huang, Y Huang, G Yuan, A Kijlstra, P Yang Sci Rep, 2016;6(0):24974. Species: Human Sample Type: Cell Culture Supernates
Analysis of receptor tyrosine kinase genetics identifies two novel risk loci in GAS6 and PROS1 in Beh�et's disease Sci Rep, 2016;6(0):26662. Species: Human Sample Type: Cell Culture Supernates
In vitro progesterone modulation on bacterial endotoxin-induced production of IL-1beta, TNFalpha, IL-6, IL-8, IL-10, MIP-1alpha, and MMP-9 in pre-labor human term placenta. Authors: Garcia-Ruiz G, Flores-Espinosa P, Preciado-Martinez E, Bermejo-Martinez L, Espejel-Nunez A, Estrada-Gutierrez G, Maida-Claros R, Flores-Pliego A, Zaga-Clavellina V Reprod Biol Endocrinol, 2015;13(0):115. Species: Human Sample Type: Cell Culture Supernates
Exposure to diesel exhaust particle extracts (DEPe) impairs some polarization markers and functions of human macrophages through activation of AhR and Nrf2. Authors: Jaguin M, Fardel O, Lecureur V PLoS ONE, 2015;10(2):e0116560. Species: Human Sample Type: Cell Culture Supernates
The effects of cytokines on spontaneous hepatitis B surface antigen seroconversion in chronic hepatitis B virus infection. Authors: Wu J, Hsu H, Chiu Y, Chen H, Ni Y, Chang M J Immunol, 2015;194(2):690-6. Species: Human Sample Type: Serum
Sourcing of an alternative pericyte-like cell type from peripheral blood in clinically relevant numbers for therapeutic angiogenic applications. Authors: Blocki A, Wang Y, Koch M, Goralczyk A, Beyer S, Agarwal N, Lee M, Moonshi S, Dewavrin J, Peh P, Schwarz H, Bhakoo K, Raghunath M Mol Ther, 2015;23(3):510-22. Species: Human Sample Type: Cell Culture Supernates
LPS-Stimulated Whole Blood Cytokine Production Is Not Related to Disease Behavior in Patients with Quiescent Crohn's Disease. Authors: Broekman M, Roelofs H, Hoentjen F, Wiegertjes R, Stoel N, Joosten L, de Jong D, Wanten G PLoS ONE, 2015;10(7):e0133932. Species: Human Sample Type: Plasma
Characterization of host and microbial determinants in individuals with latent tuberculosis infection using a human granuloma model. Authors: Guirado E, Mbawuike U, Keiser T, Arcos J, Azad A, Wang S, Schlesinger L MBio, 2015;6(1):e02537-14. Species: Human Sample Type: cell supernates
CD137 ligand signalling induces differentiation of primary acute myeloid leukaemia cells. Authors: Cheng K, Wong S, Linn Y, Ho L, Chng W, Schwarz H Br J Haematol, 2014;165(1):134-44. Species: Human Sample Type: Cell Culture Supernates
Human CD4+ T cell responses to the dog major allergen Can f 1 and its human homologue tear lipocalin resemble each other. Authors: Liukko A, Kinnunen T, Rytkonen-Nissinen M, Kailaanmaki A, Randell J, Maillere B, Virtanen T PLoS ONE, 2014;9(5):e98461. Species: Human Sample Type: Cell Culture Supernates
Tumour microenvironment of both early- and late-stage colorectal cancer is equally immunosuppressive. Authors: OToole A, Michielsen A, Nolan B, Tosetto M, Sheahan K, Mulcahy H, Winter D, Hyland J, OConnell P, Fennelly D, ODonoghue D, OSullivan J, Doherty G, Ryan E Br J Cancer, 2014;111(5):927-32. Species: Human Sample Type: Cell Culture Supernates
Quiescent innate response to infective filariae by human Langerhans cells suggests a strategy of immune evasion. Authors: Boyd A, Bennuru S, Wang Y, Sanprasert V, Law M, Chaussabel D, Nutman T, Semnani R Infect Immun, 2013;81(5):1420-9. Species: Human Sample Type: Cell Culture Supernates
Leishmania braziliensis-reactive T cells are down-regulated in long-term cured cutaneous Leishmaniasis, but the renewal capacity of T effector memory compartments is preserved. Authors: Pereira-Carvalho R, Mendes-Aguiar C, Oliveira-Neto M, Covas C, Bertho A, Da-Cruz A, Gomes-Silva A PLoS ONE, 2013;8(11):e81529. Species: Human Sample Type: Cell Culture Supernates
Association of TLR2 gene polymorphisms with ocular Behcet's disease in a Chinese Han population. Authors: Fang J, Hu R, Hou S, Ye Z, Xiang Q, Qi J, Zhou Y, Kijlstra A, Yang P Invest Ophthalmol Vis Sci, 2013;54(13):8384-92. Species: Human Sample Type: Cell Culture Supernates
Selective activation of human dendritic cells by OM-85 through a NF-kB and MAPK dependent pathway. Authors: Parola C, Salogni L, Vaira X, Scutera S, Somma P, Salvi V, Musso T, Tabbia G, Bardessono M, Pasquali C, Mantovani A, Sozzani S, Bosisio D PLoS ONE, 2013;8(12):e82867. Species: Human Sample Type: cell culture supernate
Urinary neutrophil gelatinase-associated lipocalin is a potential biomarker for renal damage in patients with systemic lupus erythematosus. Authors: Yang CC, Hsieh SC, Li KJ, Wu CH, Lu MC, Tsai CY, Yu CL J. Biomed. Biotechnol., 2012;2012(0):759313. Species: Human Sample Type: Urine
Elevated adaptive immune responses are associated with latent infections of Wuchereria bancrofti. Authors: Arndts K, Deininger S, Specht S, Klarmann U, Mand S, Adjobimey T, Debrah AY, Batsa L, Kwarteng A, Epp C, Taylor M, Adjei O, Layland LE, Hoerauf A PLoS Negl Trop Dis, 2012;6(4):e1611. Species: Human Sample Type: Cell Culture Supernates
Impact of vitamin D supplementation on markers of inflammation in adults with cystic fibrosis hospitalized for a pulmonary exacerbation. Eur J Clin Nutr, 2012;66(9):1072-4. Species: Human Sample Type: Serum
Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse. J Neuroinflammation, 2012;9(0):203. Species: Human Sample Type: Cell Culture Supernates
Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12). Authors: Suh HS, Choi N, Tarassishin L, Lee SC PLoS ONE, 2012;7(4):e35115. Species: Human Sample Type: Cell Culture Supernates
IFN-alpha blocks IL-17 production by peripheral blood mononuclear cells in Behcet's disease. Authors: Liu X, Yang P, Wang C, Li F, Kijlstra A Rheumatology (Oxford), 2011;50(2):293-8. Species: Human Sample Type: Cell Culture Supernates
Possible involvement of IL-21 and IL-10 on salivary IgA levels in chronic periodontitis subjects. Authors: Napimoga MH, Nunes LH, Maciel AA, Demasi AP, Benatti BB, Santos VR, Bastos MF, de Miranda TS, Duarte PM Scand. J. Immunol., 2011;74(6):596-602. Species: Human Sample Type: Tissue Homogenates
IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes. Authors: Pennino D, Eyerich K, Scarponi C, Carbone T, Eyerich S, Nasorri F, Garcovich S, Traidl-Hoffmann C, Albanesi C, Cavani A J. Immunol., 2010;184(9):4880-8. Species: Human Sample Type: Cell Culture Supernates
Immunoregulation of autocrine prolactin: suppressing the expression of costimulatory molecules and cytokines in T lymphocytes by prolactin receptor knockdown. Authors: Xu D, Lin L, Lin X Cell. Immunol., 2010;263(1):71-8. Species: Human Sample Type: Cell Culture Supernates
Human uterine epithelial cell secretions regulate dendritic cell differentiation and responses to TLR ligands. Authors: Ochiel DO, Ghosh M, Fahey JV J. Leukoc. Biol., 2010;88(3):435-44. Species: Human Sample Type: Cell Culture Supernates
Investigation of functional IL-10 gene polymorphism and IL-10 levels in acute graft-versus-host disease. Authors: Resende RG, Correia-Silva Jde F, Arao TC, Silva TA, Abreu MH, Bittencourt H, Gomez RS J. Clin. Immunol., 2010;30(3):465-73. Species: Human Sample Type: Saliva
PEGylation of interleukin-10 for the mitigation of enhanced pain states. Authors: Soderquist RG, Milligan ED, Harrison JA, Chavez RA, Johnson KW, Watkins LR, Mahoney MJ J Biomed Mater Res A, 2010;93(3):1169-79. Species: Human Sample Type: CSF
Anemia in Hodgkins lymphoma: the role of interleukin-6 and hepcidin. Authors: Hohaus S, Massini G, Giachelia M, Vannata B, Bozzoli V, Cuccaro A, DAlo F, Larocca LM, Raymakers RA, Swinkels DW, Voso MT, Leone G J. Clin. Oncol., 2010;28(15):2538-43. Species: Human Sample Type: Plasma
Clinical significance of interleukin-10 gene polymorphisms and plasma levels in Hodgkin lymphoma. Authors: Hohaus S, Giachelia M, Massini G, Vannata B, Criscuolo M, Martini M, DAlo F, Voso MT, Larocca LM, Leone G Leuk. Res., 2009;33(10):1352-6. Species: Human Sample Type: Plasma
Helminth antigens modulate immune responses in cells from multiple sclerosis patients through TLR2-dependent mechanisms. Authors: Correale J, Farez M J. Immunol., 2009;183(9):5999-6012. Species: Human Sample Type: Cell Culture Supernates
Reduced ex vivo interleukin-6 production by dietary fish oil is not modified by linoleic acid intake in healthy men. Authors: Damsgaard CT, Lauritzen L, Calder PC, Kjaer TR, Frokiaer H J. Nutr., 2009;139(7):1410-4. Species: Human Sample Type: Cell Culture Supernates
Divergent effects of hypoxia on dendritic cell functions. Authors: Mancino A, Schioppa T, Larghi P, Pasqualini F, Nebuloni M, Chen IH, Sozzani S, Austyn JM, Mantovani A, Sica A Blood, 2008;112(9):3723-34. Species: Human Sample Type: Cell Culture Supernates
Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12. Authors: Lamhamedi-Cherradi SE, Martin RE, Ito T, Kheradmand F, Corry DB, Liu YJ, Moyle M J. Immunol., 2008;180(9):6000-9. Species: Human Sample Type: Cell Culture Supernates
Reduced response to adiponectin and lower abundance of adiponectin receptor proteins in type 2 diabetic monocytes. Authors: Weigert J, Neumeier M, Wanninger J, Wurm S, Kopp A, Schober F, Filarsky M, Schaffler A, Zeitoun M, Aslanidis C, Buechler C FEBS Lett., 2008;582(12):1777-82. Species: Human Sample Type: Cell Culture Supernates
Adenosine receptors in regulation of dendritic cell differentiation and function. Authors: Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM Blood, 2008;112(5):1822-31. Species: Human Sample Type: Cell Culture Supernates
Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells. Authors: Spadaro M, Caorsi C, Ceruti P, Varadhachary A, Forni G, Pericle F, Giovarelli M FASEB J., 2008;22(8):2747-57. Species: Human Sample Type: Cell Culture Supernates
Helminth infections associated with multiple sclerosis induce regulatory B cells. Authors: Correale J, Farez M, Razzitte G Ann. Neurol., 2008;64(2):187-99. Species: Human Sample Type: Cell Culture Supernates
Early cytokine responses after percutaneous magnetic resonance imaging guided laser thermoablation of malignant liver tumors. Authors: Kallio R, Sequeiros R, Surcel HM, Ohtonen P, Kiviniemi H, Syrjala H Cytokine, 2007;34(5):278-83.
Human tumor-derived exosomes selectively impair lymphocyte responses to interleukin-2. Authors: Clayton A, Mitchell JP, Court J, Mason MD, Tabi Z Cancer Res., 2007;67(15):7458-66.
Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells. Authors: Duluc D, Delneste Y, Tan F, Moles MP, Grimaud L, Lenoir J, Preisser L, Anegon I, Catala L, Ifrah N, Descamps P, Gamelin E, Gascan H, Hebbar M, Jeannin P Blood, 2007;110(13):4319-30. Species: Human Sample Type: Cell Culture Supernates
The differential effect of Eriobotrya japonica hydrophilic leaf extract on cytokines production and modulation. Authors: Matalka KZ, Ali D, Khawad AE, Qadan F Cytokine, 2007;40(3):235-40. Species: Human Sample Type: Cell Culture Supernates
Airway remodelling in children with cystic fibrosis. Authors: Hilliard TN, Regamey N, Shute JK, Nicholson AG, Alton EW, Bush A, Davies JC Thorax, 2007;62(12):1074-80.
B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease. Authors: Kawai T, Matsuyama T, Hosokawa Y, Makihira S, Seki M, Karimbux NY, Goncalves RB, Valverde P, Dibart S, Li YP, Miranda LA, Ernst CW, Izumi Y, Taubman MA Am. J. Pathol., 2006;169(3):987-98. Species: Human Sample Type: Tissue Homogenates
Splice variants of human FOXP3 are functional inhibitors of human CD4+ T-cell activation. Authors: Smith EL, Finney HM, Nesbitt AM, Ramsdell F, Robinson MK Immunology, 2006;119(2):203-11.
Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists. Authors: Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M, Cavaillon JM, Philpott DJ, Adib-Conquy M Eur. J. Immunol., 2005;35(8):2459-70. Species: Human Sample Type: Cell Culture Supernates
Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt's lymphoma. Authors: Pound JD, Batth BK, Johannessen I, Wood K J. Immunol., 2005;174(5):3015-23. Species: Human Sample Type: Cell Culture Supernates
Association of type 2 cytokines with hepatic fibrosis in human Schistosoma mansoni infection. Authors: de Jesus AR, Magalhaes A, Miranda DG, Miranda RG, Araujo MI, de Jesus AA, Silva A, Santana LB, Pearce E, Carvalho EM Infect. Immun., 2004;72(6):3391-7. Species: Human Sample Type: Cell Culture Supernates
The Toll-like receptor-2/6 agonist macrophage-activating lipopeptide-2 cooperates with IFN-gamma to reverse the Th2 skew in an in vitro allergy model. Authors: Weigt H, Muhlradt PF, Larbig M, Krug N, Braun A J. Immunol., 2004;172(10):6080-6. Species: Human Sample Type: Cell Culture Supernates
Differential effect of serotonin on cytokine production in lipopolysaccharide-stimulated human peripheral blood mononuclear cells: involvement of 5-hydroxytryptamine2A receptors. Authors: Cloez-Tayarani I, Petit-Bertron AF, Venters HD, Cavaillon JM Int. Immunol., 2003;15(2):233-40. Species: Human Sample Type: Cell Culture Supernates
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