The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling.
Authors: Fleming B, Chandrasekaran P, Dillon L, Dalby E, Suresh R, Sarkar A, El-Sayed N, Mosser D
J Leukoc Biol, 2015;98(3):395-407.
Species: Human
Sample Type: Cell Culture Supernates

The effects of cytokines on spontaneous hepatitis B surface antigen seroconversion in chronic hepatitis B virus infection.
Authors: Wu J, Hsu H, Chiu Y, Chen H, Ni Y, Chang M
J Immunol, 2015;194(2):690-6.
Species: Human
Sample Type: Serum

Characterization of host and microbial determinants in individuals with latent tuberculosis infection using a human granuloma model.
Authors: Guirado E, Mbawuike U, Keiser T, Arcos J, Azad A, Wang S, Schlesinger L
MBio, 2015;6(1):e02537-14.
Species: Human
Sample Type: cell supernates

Exposure to diesel exhaust particle extracts (DEPe) impairs some polarization markers and functions of human macrophages through activation of AhR and Nrf2.
Authors: Jaguin M, Fardel O, Lecureur V
PLoS ONE, 2015;10(2):e0116560.
Species: Human
Sample Type: Cell Culture Supernates

Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells.
Authors: Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G
Circulation, 2009;119(10):1424-32.
Species: Human
Sample Type: Plasma

Expression of soluble vascular endothelial growth factor receptor-1 in human monocyte-derived mature dendritic cells contributes to their antiangiogenic property.
Authors: Kishuku M, Nishioka Y, Abe S, Kishi J, Ogino H, Aono Y, Azuma M, Kinoshita K, Batmunkh R, Rentsenhand B, Makino H, Ranjan P, Minakuchi K, Sone S
J. Immunol., 2009;183(12):8176-85.
Species: Human
Sample Type: Cell Culture Supernates

Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12.
Authors: Lamhamedi-Cherradi SE, Martin RE, Ito T, Kheradmand F, Corry DB, Liu YJ, Moyle M
J. Immunol., 2008;180(9):6000-9.
Species: Human
Sample Type: Cell Culture Supernates

B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease.
Authors: Kawai T, Matsuyama T, Hosokawa Y, Makihira S, Seki M, Karimbux NY, Goncalves RB, Valverde P, Dibart S, Li YP, Miranda LA, Ernst CW, Izumi Y, Taubman MA
Am. J. Pathol., 2006;169(3):987-98.
Species: Human
Sample Type: Tissue Homogenates

The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation.
Authors: Blumenthal A, Ehlers S, Lauber J, Buer J, Lange C, Goldmann T, Heine H, Brandt E, Reiling N
Blood, 2006;108(3):965-73.
Species: Human
Sample Type: Cell Culture Supernates

A combination of E. coli DNA fragments and modified lipopolysaccharides as a cancer immunotherapy.
Authors: Cho YJ, Ahn BY, Lee NG, Lee DH, Kim DS
Vaccine, 2006;24(31):5862-71.
Species: Human
Sample Type: Cell Culture Supernates

The direct effects of Toll-like receptor ligands on human NK cell cytokine production and cytotoxicity.
Authors: Lauzon NM, Mian F, MacKenzie R, Ashkar AA
Cell. Immunol., 2006;241(2):102-12.
Species: Human
Sample Type: Cell Culture Supernates

Transmission of Mycobacterium tuberculosis undetected by tuberculin skin testing.
Authors: Anderson ST, Williams AJ, Brown JR, Newton SM, Simsova M, Nicol MP, Sebo P, Levin M, Wilkinson RJ, Wilkinson KA
Am. J. Respir. Crit. Care Med., 2006;173(9):1038-42.
Species: Human
Sample Type: Cell Culture Supernates

Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists.
Authors: Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M, Cavaillon JM, Philpott DJ, Adib-Conquy M
Eur. J. Immunol., 2005;35(8):2459-70.
Species: Human
Sample Type: Cell Culture Supernates

Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody.
Authors: Asselin-Paturel C, Brizard G, Pin JJ, Briere F, Trinchieri G
J. Immunol., 2003;171(12):6466-77.
Species: Mouse
Sample Type: Cell Culture Supernates

Interleukin 12 (IL-12), also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. The IL-12 p40 subunit is shared by IL-23, another heterodimeric cytokine that has biological activities similar to, as well as distinct from, IL-12. IL-12 is produced by macrophages and B cells and has been shown to have multiple effects on T cells and natural killer (NK) cells. While mouse IL-12 is active on both human and mouse cells, human IL-12 is not active on mouse cells.