R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. On the cytokine/chemokine network during Plasmodium vivax malaria: new insights to understand the disease Authors: NS Hojo-Souza, DB Pereira, FS de Souza, TA de Oliveir, MS Cardoso, MS Tada, GM Zanini, DC Bartholome, RT Fujiwara, LL Bueno Malar. J, 2017;16(1):42. Species: Human Sample Type: Plasma
Mumps Virus Induces Protein-Kinase-R-Dependent Stress Granules, Partly Suppressing Type III Interferon Production PLoS ONE, 2016;11(8):e0161793. Species: Human Sample Type: Cell Culture Supernates
Bortezomib treatment sensitizes oncolytic HSV-1 treated tumors to NK cell immunotherapy Clin Cancer Res, 2016;0(0):. Species: Mouse Sample Type: Serum
Dual Inhibition of Rip2 and IRAK1/4 Regulates IL-1? and IL-6 in Sarcoidosis Alveolar Macrophages and Peripheral Blood Mononuclear Cells J Immunol, 2016;0(0):. Species: Human Sample Type: Cell Culture Supernates
Analysis of receptor tyrosine kinase genetics identifies two novel risk loci in GAS6 and PROS1 in Beh�et's disease Sci Rep, 2016;6(0):26662. Species: Human Sample Type: Cell Culture Supernates
Reduced systemic and mycobacterial antigen-stimulated concentrations of IL-1? and IL-18 in tuberculous lymphadenitis Cytokine, 2016;90(0):66-72. Species: Human Sample Type: Whole Blood Supernates
DNA Sensing via TLR-9 Constitutes a Major Innate Immunity Pathway Activated during Erythema Nodosum Leprosum J Immunol, 2016;0(0):. Species: Human Sample Type: Cell Culture Supernates
Acanthamoeba castellanii (Genotype T4) Stimulates the Production of Interleukin-10 as well as Pro-inflammatory Cytokines in THP-1 Cells, Human Peripheral Blood Mononuclear Cells and Human Monocyte-Derived Macrophages Infect Immun, 2016;0(0):. Species: Human Sample Type: Cell Culture Supernates
An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells. Authors: Campia I, Buondonno I, Castella B, Rolando B, Kopecka J, Gazzano E, Ghigo D, Riganti C PLoS ONE, 2015;10(5):e0126159. Species: Human Sample Type: Cell Culture Supernates
Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1beta, IFN-beta, and IL-15 Pathways. Authors: Mattiola I, Pesant M, Tentorio P, Molgora M, Marcenaro E, Lugli E, Locati M, Mavilio D J Immunol, 2015;195(6):2818-28. Species: Human Sample Type: Cell Culture Supernates
UNC-45A Is a Nonmuscle Myosin IIA Chaperone Required for NK Cell Cytotoxicity via Control of Lytic Granule Secretion. Authors: Iizuka Y, Cichocki F, Sieben A, Sforza F, Karim R, Coughlin K, Isaksson Vogel R, Gavioli R, McCullar V, Lenvik T, Lee M, Miller J, Bazzaro M J Immunol, 2015;195(10):4760-70. Species: Human Sample Type: Cell Culture Supernates
B7H6-Specific Bispecific T Cell Engagers Lead to Tumor Elimination and Host Antitumor Immunity. Authors: Wu M, Zhang T, Gacerez A, Coupet T, DeMars L, Sentman C J Immunol, 2015;194(11):5305-11.
B7H6-specific chimeric antigen receptors lead to tumor elimination and host antitumor immunity. Authors: Wu M, Zhang T, DeMars L, Sentman C Gene Ther, 2015;22(8):675-84.
Interleukin-23 Receptor Gene Polymorphism May Enhance Expression of the IL-23 Receptor, IL-17, TNF-alpha and IL-6 in Behcet's Disease. Authors: Jiang Z, Hennein L, Tao Y, Tao L PLoS ONE, 2015;10(7):e0134632. Species: Human Sample Type: Cell Culture Supernates
Characterization of host and microbial determinants in individuals with latent tuberculosis infection using a human granuloma model. Authors: Guirado E, Mbawuike U, Keiser T, Arcos J, Azad A, Wang S, Schlesinger L MBio, 2015;6(1):e02537-14. Species: Human Sample Type: cell supernates
Phenotypic profiling of CD8(+) T cells during Plasmodium vivax blood-stage infection. Authors: Hojo-Souza N, Pereira D, Passos L, Gazzinelli-Guimaraes P, Cardoso M, Tada M, Zanini G, Bartholomeu D, Fujiwara R, Bueno L BMC Infect Dis, 2015;15(0):35. Species: Human Sample Type: Plasma
T-cell engager-armed oncolytic vaccinia virus significantly enhances antitumor therapy. Authors: Yu F, Wang X, Guo Z, Bartlett D, Gottschalk S, Song X Mol Ther, 2014;22(1):102-11. Species: Human Sample Type: Cell Culture Supernates
Interferon-gamma production by human neutrophils upon stimulation by IL-12, IL-15 and IL-18 and challenge with Paracoccidioides brasiliensis. Authors: Rodrigues D, Fernandes R, Balderramas H, Penitenti M, Bachiega T, Calvi S, Dias-Melicio L, Ikoma M, Soares A Cytokine, 2014;69(1):102-9. Species: Human Sample Type: Cell Culture Supernates
CD137 ligand signalling induces differentiation of primary acute myeloid leukaemia cells. Authors: Cheng K, Wong S, Linn Y, Ho L, Chng W, Schwarz H Br J Haematol, 2014;165(1):134-44. Species: Human Sample Type: Cell Culture Supernates
TNF-alpha blockade induces IL-10 expression in human CD4+ T cells. Authors: Evans H, Roostalu U, Walter G, Gullick N, Frederiksen K, Roberts C, Sumner J, Baeten D, Gerwien J, Cope A, Geissmann F, Kirkham B, Taams L Nat Commun, 2014;5(0):3199. Species: Human Sample Type: Cell Culture Supernates
Human CD4+ T cell responses to the dog major allergen Can f 1 and its human homologue tear lipocalin resemble each other. Authors: Liukko A, Kinnunen T, Rytkonen-Nissinen M, Kailaanmaki A, Randell J, Maillere B, Virtanen T PLoS ONE, 2014;9(5):e98461.
Specific targeting of a naturally presented osteosarcoma antigen, papillomavirus binding factor peptide, using an artificial monoclonal antibody. Authors: Tsukahara T, Emori M, Murata K, Hirano T, Muroi N, Kyono M, Toji S, Watanabe K, Torigoe T, Kochin V, Asanuma H, Matsumiya H, Yamashita K, Himi T, Ichimiya S, Wada T, Yamashita T, Hasegawa T, Sato N J Biol Chem, 2014;289(32):22035-47. Species: Human Sample Type: Cell Culture Supernates
A functional variant of PTPN22 confers risk for Vogt-Koyanagi-Harada syndrome but not for ankylosing spondylitis. Authors: Zhang Q, Qi J, Hou S, DU L, Yu H, Cao Q, Zhou Y, Liao D, Kijlstra A, Yang P PLoS ONE, 2014;9(5):e96943. Species: Human Sample Type: Cell Culture Supernates
TLR3 impairment in human newborns. Authors: Slavica L, Nordstrom I, Karlsson M, Valadi H, Kacerovsky M, Jacobsson B, Eriksson K J Leukoc Biol, 2013;94(5):1003-11. Species: Human Sample Type: Cell Culture Supernates
CD137L-stimulated dendritic cells are more potent than conventional dendritic cells at eliciting cytotoxic T-cell responses. Authors: Harfuddin Z, Kwajah S, Chong Nyi Sim A, Macary P, Schwarz H Oncoimmunology, 2013;2(11):e26859. Species: Human Sample Type: Cell culture supernatant
Elevated adaptive immune responses are associated with latent infections of Wuchereria bancrofti. Authors: Arndts K, Deininger S, Specht S, Klarmann U, Mand S, Adjobimey T, Debrah AY, Batsa L, Kwarteng A, Epp C, Taylor M, Adjei O, Layland LE, Hoerauf A PLoS Negl Trop Dis, 2012;6(4):e1611. Species: Human Sample Type: Cell Culture Supernates
IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist. Authors: van de Veerdonk FL, Stoeckman AK, Wu G, Boeckermann AN, Azam T, Netea MG, Joosten LA, Van der Meer JW, Hao R, Kalabokis V, Dinarello CA Proc. Natl. Acad. Sci. U.S.A., 2012;109(8):3001-5. Species: Human Sample Type: Cell Culture Supernates
NKG2D receptor regulates human effector T-cell cytokine production. Authors: Barber A, Sentman CL Blood, 2011;117(24):6571-81. Species: Human Sample Type: Cell Culture Supernates
Mutations of the von Hippel-Lindau gene confer increased susceptibility to natural killer cells of clear-cell renal cell carcinoma. Authors: Perier A, Fregni G, Wittnebel S, Gad S, Allard M, Gervois N, Escudier B, Azzarone B, Caignard A Oncogene, 2011;30(23):2622-32. Species: Human Sample Type: Cell Culture Supernates
Elevated serum osteopontin levels and genetic polymorphisms of osteopontin are associated with Vogt-Koyanagi-Harada disease. Authors: Chu M, Yang P, Hu R, Hou S, Li F, Chen Y, Kijlstra A Invest. Ophthalmol. Vis. Sci., 2011;52(10):7084-9. Species: Human Sample Type: Cell Culture Supernates
Serum levels of Th17-related cytokines in Behcet disease patients after cataract surgery. Authors: Jiang S, Liu X, Luo L, Qu B, Huang X, Lin Y, Ye S, Liu Y Mol. Vis., 2011;17(0):1425-30. Species: Human Sample Type: Serum
The effects of vaccine timing on the efficacy of an acute eccentric exercise intervention on the immune response to an influenza vaccine in young adults. Authors: Campbell JP, Edwards KM, Ring C Brain Behav. Immun., 2010;24(2):236-42. Species: Human Sample Type: Plasma
Immunoregulation of autocrine prolactin: suppressing the expression of costimulatory molecules and cytokines in T lymphocytes by prolactin receptor knockdown. Authors: Xu D, Lin L, Lin X Cell. Immunol., 2010;263(1):71-8. Species: Human Sample Type: Cell Culture Supernates
IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes. Authors: Pennino D, Eyerich K, Scarponi C, Carbone T, Eyerich S, Nasorri F, Garcovich S, Traidl-Hoffmann C, Albanesi C, Cavani A J. Immunol., 2010;184(9):4880-8. Species: Human Sample Type: Cell Culture Supernates
Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma. Authors: Maneechotesuwan K, Wamanuttajinda V, Kasetsinsombat K, Huabprasert S, Yaikwawong M, Barnes PJ, Wongkajornsilp A J. Allergy Clin. Immunol., 2009;123(1):239-48. Species: Human Sample Type: Cell Culture Supernates
Detuning CD8+ T lymphocytes by down-regulation of the activating receptor NKG2D: role of NKG2D ligands released by activated T cells. Authors: Cerboni C, Ardolino M, Santoni A, Zingoni A Blood, 2009;113(13):2955-64. Species: Human Sample Type: Cell Culture Supernates
Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Authors: Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G Circulation, 2009;119(10):1424-32. Species: Human Sample Type: Plasma
TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23. Authors: Aliahmadi E, Gramlich R, Grutzkau A, Hitzler M, Kruger M, Baumgrass R, Schreiner M, Wittig B, Wanner R, Peiser M Eur. J. Immunol., 2009;39(5):1221-30. Species: Human Sample Type: Cell Culture Supernates
Interferon-beta treatment in multiple sclerosis attenuates inflammatory gene expression through inducible activity of the phosphatase SHP-1. Authors: Christophi GP, Panos M, Hudson CA, Tsikkou C, Mihai C, Mejico LJ, Jubelt B, Massa PT Clin. Immunol., 2009;133(1):27-44. Species: Human Sample Type: Plasma
Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12. Authors: Lamhamedi-Cherradi SE, Martin RE, Ito T, Kheradmand F, Corry DB, Liu YJ, Moyle M J. Immunol., 2008;180(9):6000-9. Species: Human Sample Type: Cell Culture Supernates
Helminth infections associated with multiple sclerosis induce regulatory B cells. Authors: Correale J, Farez M, Razzitte G Ann. Neurol., 2008;64(2):187-99. Species: Human Sample Type: Cell Culture Supernates
alpha1beta1 integrin and interleukin-7 receptor up-regulate the expression of RANKL in human T cells and enhance their osteoclastogenic function. Authors: Gendron S, Boisvert M, Chetoui N, Aoudjit F Immunology, 2008;125(0):359. Species: Human Sample Type: Cell Culture Supernates
Diminished frequency and function of CD4+CD25high regulatory T cells associated with active uveitis in Vogt-Koyanagi-Harada syndrome. Authors: Chen L, Yang P, Zhou H, He H, Ren X, Chi W, Wang L, Kijlstra A Invest. Ophthalmol. Vis. Sci., 2008;49(8):3475-82. Species: Human Sample Type: Cell Culture Supernates
Adenosine receptors in regulation of dendritic cell differentiation and function. Authors: Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM Blood, 2008;112(5):1822-31. Species: Human Sample Type: Cell Culture Supernates
Neuroimmune crosstalk in asthma: dual role of the neurotrophin receptor p75NTR. Authors: Nassenstein C, Kammertoens T, Veres TZ, Uckert W, Spies E, Fuchs B, Krug N, Braun A J. Allergy Clin. Immunol., 2007;120(5):1089-96. Species: Mouse Sample Type: BALF
Chimeric NKG2D receptor-bearing T cells as immunotherapy for ovarian cancer. Authors: Barber A, Zhang T, DeMars LR, Conejo-Garcia J, Roby KF, Sentman CL Cancer Res., 2007;67(10):5003-8. Species: Human Sample Type: Cell Culture Supernates
IL-24 modulates IFN-gamma expression in patients with tuberculosis. Authors: Wu B, Huang C, Kato-Maeda M, Hopewell PC, Daley CL, Krensky AM, Clayberger C Immunol. Lett., 2007;117(1):57-62. Species: Human Sample Type: Cell Culture Supernates
The differential effect of Eriobotrya japonica hydrophilic leaf extract on cytokines production and modulation. Authors: Matalka KZ, Ali D, Khawad AE, Qadan F Cytokine, 2007;40(3):235-40. Species: Human Sample Type: Cell Culture Supernates
The direct effects of Toll-like receptor ligands on human NK cell cytokine production and cytotoxicity. Authors: Lauzon NM, Mian F, MacKenzie R, Ashkar AA Cell. Immunol., 2006;241(2):102-12. Species: Human Sample Type: Cell Culture Supernates
An investigation of auto-reactivity after head injury. Authors: Cox AL, Coles AJ, Nortje J, Bradley PG, Chatfield DA, Thompson SJ, Menon DK J. Neuroimmunol., 2006;174(1):180-6. Species: Human Sample Type: Cell Culture Supernates
A combination of E. coli DNA fragments and modified lipopolysaccharides as a cancer immunotherapy. Authors: Cho YJ, Ahn BY, Lee NG, Lee DH, Kim DS Vaccine, 2006;24(31):5862-71. Species: Human Sample Type: Cell Culture Supernates
IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate. Authors: Miranda-Carus ME, Balsa A, Benito-Miguel M, Perez de Ayala C, Martin-Mola E J. Immunol., 2004;173(2):1463-76. Species: Human Sample Type: Cell Culture Supernates
Immune responses in normal Indian langur monkeys (Presbytis entellus)--a primate model for visceral leishmaniasis. Authors: Misra A, Dube A, Naik S J. Med. Primatol., 2004;33(2):65-9. Species: Primate - Presbytis entellus (Indian langur) Sample Type: Cell Culture Supernates
Association of type 2 cytokines with hepatic fibrosis in human Schistosoma mansoni infection. Authors: de Jesus AR, Magalhaes A, Miranda DG, Miranda RG, Araujo MI, de Jesus AA, Silva A, Santana LB, Pearce E, Carvalho EM Infect. Immun., 2004;72(6):3391-7. Species: Human Sample Type: Cell Culture Supernates
The Toll-like receptor-2/6 agonist macrophage-activating lipopeptide-2 cooperates with IFN-gamma to reverse the Th2 skew in an in vitro allergy model. Authors: Weigt H, Muhlradt PF, Larbig M, Krug N, Braun A J. Immunol., 2004;172(10):6080-6. Species: Human Sample Type: Cell Culture Supernates
Activation of resting human primary T cells with chimeric receptors: costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain. Authors: Finney HM, Akbar AN, Lawson AD J. Immunol., 2004;172(1):104-13. Species: Human Sample Type: Cell Culture Supernates
Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. Authors: Groh V, Bruhl A, El-Gabalawy H, Nelson JL, Spies T Proc. Natl. Acad. Sci. U.S.A., 2003;100(16):9452-7. Species: Human Sample Type: Cell Culture Supernates
Toxoplasma gondii induces granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor secretion by human fibroblasts: implications for neutrophil apoptosis. Authors: Channon JY, Miselis KA, Minns LA, Dutta C, Kasper LH Infect. Immun., 2002;70(11):6048-57. Species: Human Sample Type: Cell Culture Supernates
Natural killer cell-produced IFN-gamma and TNF-alpha induce target cell cytolysis through up-regulation of ICAM-1. Authors: Wang R, Jaw JJ, Jaw J, Stutzman N, Stutzman NC, Zou Z, Sun PD J Leukoc Biol, 0;91(2):299-309. Species: Human Sample Type: Cell Culture Supernates
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