Cleaved Caspase-8 (Asp387) (D5B2) XP® Rabbit mAb (Mouse Specific) (PE Conjugate)
货号：
14071S 基本售价：
4460.0 元 规格：
100ul
产品信息
概述| 货号 | 14071S |
| 反应种属 | Mouse |
| 来源宿主 | Rabbit |
| 应用 | F |
| 使用方法 | F(1:50) |
性能| 供应商 | CST |
| 标记 | PE |
| 背景 | Apoptosis induced through the CD95 receptor (Fas/APO-1) and tumor necrosis factor receptor 1 (TNFR1) activates caspase-8 and leads to the release of the caspase-8 active fragments, p18 and p10 (1-3). Activated caspase-8 cleaves and activates downstream effector caspases such as caspase-1, -3, -6, and -7. Caspase-3 ultimately elicits the morphological hallmarks of apoptosis, including DNA fragmentation and cell shrinkage. |
| 存放说明 | 4C |
参考图片Flow cytometric analysis of Raw 264.7 cells, untreated (blue) or treated with Cycloheximide #2112 (10 μg/ml, overnight) and mTNF-α #5178 (20 ng/ml, 4 hr; green), using Cleaved Caspase-8 (Asp387) (D5B2) XP® Rabbit mAb (Mouse Specific) (PE Conjugate). |
