IRF-1 (D5E4) XP® Rabbit mAb (PE Conjugate)
货号：
12732S 基本售价：
4264.0 元 规格：
100ul
产品信息
概述| 货号 | 12732S |
| 描述 | This Cell Signaling Technology antibody is conjugated to phycoerythrin (PE) and tested in-house for direct flow cytometry analysis in human cells. The antibody is expected to exhibit the same species cross-reactivity as the unconjugated IRF-1 (D5E4) XP® Rabbit mAb #8478. |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | F |
| 目标/特异性 | IRF-1 (D5E4) XP® Rabbit mAb (PE Conjugate) recognizes endogenous levels of total IRF-1 protein. |
| 使用方法 | F(1:50) |
性能| 供应商 | CST |
| 标记 | PE |
| 背景 | Interferon regulatory factors (IRFs) comprise a family of transcription factors that function within the Jak/Stat pathway to regulate interferon (IFN) and IFN-inducible gene expression in response to viral infection (1). IRFs play an important role in pathogen defense, autoimmunity, lymphocyte development, cell growth, and susceptibility to transformation. The IRF family includes nine members: IRF-1, IRF-2, ISGF3γ/p48, IRF-3, IRF-4 (Pip/LSIRF/ICSAT), IRF-5, IRF-6, IRF-7, and IRF-8/ICSBP. All IRF proteins share homology in their amino-terminal DNA-binding domains. IRF family members regulate transcription through interactions with proteins that share similar DNA-binding motifs, such as IFN-stimulated response elements (ISRE), IFN consensus sequences (ICS), and IFN regulatory elements (IRF-E) (2). |
| 存放说明 | 4C |
参考图片Flow cytometric analysis of HeLa cells, untreated (blue) or treated with Human Interferon-γ (hIFN-γ) #8901 (green), using IRF-1 (D5E4) XP® Rabbit mAb (PE Conjugate).流式细胞术分析HeLa细胞，未处理（蓝色）或Human Interferon-γ (hIFN-γ) #8901处理（绿色），使用抗体是IRF-1 (D5E4) XP® Rabbit mAb (PE Conjugate)。 |
