Jak2 (D2E12) XP® Rabbit mAb (PE Conjugate)
货号：
5941S 基本售价：
4264.0 元 规格：
100ul
产品信息
概述| 货号 | 5941S |
| 描述 | This Cell Signaling Technology antibody is conjugated to phycoerythrin (PE) and tested in-house for direct flow cytometry analysis in human cells. The antibody is expected to exhibit the same species cross-reactivity as the unconjugated Jak2 (D2E12) XP® Rabbit mAb #3230. |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | F |
| 目标/特异性 | Jak2 (D2E12) XP® Rabbit mAb (PE Conjugate) detects endogenous levels of total Jak2 protein. No cross-reactivity was observed with other family members. |
| 使用方法 | F(1:50) |
性能| 供应商 | CST |
| 标记 | PE |
| 背景 | Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3, and Tyk2) are activated by ligands binding to a number of associated cytokine receptors (1). Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats (2), Shc (3), insulin receptor substrates (4), and focal adhesion kinase (FAK) (5), typically contain SH2 or other phospho-tyrosine-binding domains. |
| 存放说明 | 4C |
参考图片Flow cytometric analysis of K-562 cells using Jak2 (D2E12) XP® Rabbit mAb (PE Conjugate) (green) compared to concentration-matched Rabbit (DA1E) mAb IgG XP® Isotype Control (PE Conjugate) #5742 (red).流式细胞仪分析K-562 细胞，所用抗体为Jak2 (D2E12) XP® Rabbit mAb (PE Conjugate)(绿色) 与浓度相匹配的Rabbit (DA1E) mAb IgG XP® Isotype Control (PE Conjugate) #5742 抗体(红色)对比。 |
