Bcl-xL (54H6) Rabbit mAb (Alexa Fluor® 488 Conjugate)
货号：
2767S 基本售价：
4060.0 元 规格：
100ul
产品信息
概述| 货号 | 2767S |
| 描述 | This Cell Signaling Technology antibody is conjugated to Alexa Fluor® 488 fluorescent dye and tested in-house for direct flow cytometric analysis of human cells. The unconjugated antibody #2764 reacts with human, mouse, rat and monkey Bcl-xL protein. CST expects that Bcl-xL (54H6) Rabbit mAb (Alexa Fluor® 488 Conjugate) will also recognize Bcl-xL in these species. |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | F |
| 使用方法 | F(1:50) |
性能| 供应商 | CST |
| 标记 | Alexa Fluor 488 |
| 背景 | Bcl-xL prevents apoptosis through two different mechanisms: heterodimerization with an apoptotic protein inhibits its apoptotic effect (1,2) and formation of mitochondrial outer membrane pores help maintain a normal membrane state under stressful conditions (3). Bcl-xL is phosphorylated by JNK following treatment with microtubule-damaging agents such as paclitaxel, vinblastine and nocodazole (4,5). |
| 存放说明 | 4C |
参考图片Flow cytometric analysis of SEM (blue) and K-562 (green) cells using Bcl-xL (54H6) Rabbit mAb (Alexa Fluor® 488 Conjugate) compared to nonspecific Rabbit IgG Isotype Control (Alexa Fluor® 488 Conjugate) #4340 (red). 流式细胞仪分析SEM (蓝色) 和 K-562 (绿色)细胞，所用抗体为Bcl-xL (54H6) Rabbit mAb (Alexa Fluor® 488 Conjugate)兔单抗，非特异性的Rabbit IgG Isotype Control (Alexa Fluor® 488 Conjugate) #4340 (红色)做比对。 |
