Insulin (C27C9) Rabbit mAb (PE Conjugate)
货号:
8508S 基本售价:
4060.0 元 规格:
100ul
产品信息
概述货号 | 8508S |
描述 | This Cell Signaling Technology antibody is conjugated to phycoerythrin (PE) and tested in-house for direct flow cytometry analysis in human and mouse cells. The antibody is expected to exhibit the same species cross-reactivity as the unconjugated Insulin (C27C9) Rabbit mAb #3014. |
反应种属 | Mouse |
来源宿主 | Rabbit |
应用 | F |
目标/特异性 | Insulin (C27C9) Rabbit mAb (PE Conjugate) detects endogenous levels of total insulin protein. |
使用方法 | F(1:50) |
性能供应商 | CST |
标记 | PE |
背景 | The maintenance of glucose homeostasis is an essential physiological process that is regulated by hormones. An elevation in blood glucose levels during feeding stimulates insulin release from pancreatic β cells through a glucose sensing pathway (1). Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Insulin stimulates glucose uptake from blood into skeletal muscle and adipose tissue. Insulin deficiency leads to type 1 diabetes mellitus (2). |
存放说明 | 4C |
参考图片Flow cytometric analysis of HeLa (blue) and β-TC-6 (green) cells using Insulin (C27C9) Rabbit mAb (PE Conjugate). 对HeLa(蓝)和β-TC-6(绿)细胞使用Insulin (C27C9) Rabbit mAb兔单抗 (PE Conjugate)进行流式细胞仪分析。 |