Oct-4A (C30A3) Rabbit mAb (PE Conjugate)
货号:
56159S 基本售价:
4060.0 元 规格:
100ul
产品信息
概述货号 | 56159S |
反应种属 | Human/Mouse |
来源宿主 | Rabbit IgG |
应用 | F |
使用方法 | F(1:50) |
性能供应商 | CST |
背景 | Oct-4 (POU5F1) is a transcription factor highly expressed in undifferentiated embryonic stem cells and embryonic germ cells (1). A network of key factors that includes Oct-4, Nanog, and Sox2 is necessary for the maintenance of pluripotent potential, and downregulation of Oct-4 has been shown to trigger cell differentiation (2,3). Research studies have demonstrated that Oct-4 is a useful germ cell tumor marker (4). Oct-4 exists as two splice variants, Oct-4A and Oct-4B (5). Recent studies have suggested that the Oct-4A isoform has the ability to confer and sustain pluripotency, while Oct-4B may exist in some somatic, non-pluripotent cells (6,7). |
存放说明 | 4C |
参考图片Flow cytometric analysis of HeLa (blue) and NTERA-2 (green) cells using Oct-4A (C30A3) Rabbit mAb (PE Conjugate). |