Phospho-p90RSK (Ser380) (D5D8) Rabbit mAb (Alexa Fluor® 488 Conjugate)
货号:
13588S 基本售价:
4060.0 元 规格:
100ul
产品信息
概述货号 | 13588S |
反应种属 | Human/Mouse/Rat/Monkey |
来源宿主 | Rabbit |
应用 | F |
使用方法 | F(1:50) |
性能供应商 | CST |
标记 | Alexa Fluor 488 |
背景 | The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases characterized by two nonidentical, functional kinase domains (1) and a carboxy-terminal docking site for extracellular signal-regulated kinases (ERKs) (2). Several sites both within and outside of the RSK kinase domain, including Ser380, Thr359, Ser363, and Thr573, are important for kinase activation (3). RSK1-3 are activated via coordinated phosphorylation by MAPKs, autophosphorylation, and phosphoinositide-3-OH kinase (PI3K) in response to many growth factors, polypeptide hormones, and neurotransmitters (3). |
存放说明 | 4C |
参考图片Flow cytometric analysis of Jurkat cells, untreated (blue) or treated with TPA #4174 (green), using Phospho-p90RSK (Ser380) (D5D8) Rabbit mAb (Alexa Fluor® 488 Conjugate). |