Phospho-Stat5 (Tyr694) (C71E5) Rabbit mAb (PE Conjugate)
货号：
5387S 基本售价：
4060.0 元 规格：
100ul
产品信息
概述| 货号 | 5387S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Rabbit |
| 应用 | F |
| 使用方法 | F(1:50) |
性能| 供应商 | CST |
| 标记 | PE |
| 背景 | Stat5 is activated in response to a wide variety of ligands including IL-2, GM-CSF, growth hormone and prolactin. Phosphorylation at Tyr694 is obligatory for Stat5 activation (1,2). This phosphorylation is mediated by Src upon erythropoietin stimulation (3). Stat5 is constitutively active in some leukemic cell types (4). Phosphorylated Stat5 is found in some endothelial cells treated with IL-3, which suggests its involvement in angiogenesis and cell motility (5). Stat5a and Stat5b are independently regulated and activated in various cell types. For instance, interferon treatment predominantly activates Stat5a in U-937 cells and Stat5b in HeLa cells (6). |
| 存放说明 | 4C |
参考图片Flow cytometric analysis of TF-1 cells, untreated (blue) or treated with hGM-CSF #8922 (green), using Phospho-Stat5 (Tyr694) (C71E5) Rabbit mAb (PE Conjugate). |
