一抗

克隆类型
多抗单抗
产品类型
标签抗体磷酸化抗体内参抗体甲基化抗体乙酰化抗体药物与化合物抗体植物抗体
研究领域
肿瘤心血管细胞生物免疫学发育生物学染色质和核信号微生物学细胞凋亡信号转导干细胞神经生物学生长因子和激素糖尿病内分泌病转运蛋白植物细菌及病毒转录调节因子海洋生物上皮细胞趋化因子结合蛋白细胞表面分子G蛋白偶联受体胶原蛋白糖蛋白交换蛋白细胞分化血管内皮细胞细胞类型标志物内皮细胞淋巴细胞T-淋巴细胞B-淋巴细胞细胞粘附分子肿瘤细胞生物标志物骨髓细胞细胞骨架跨膜蛋白细胞因子自然杀伤细胞树突状细胞标志物脂蛋白新陈代谢锌指蛋白通道蛋白细胞周期蛋白激酶和磷酸酶昆虫线粒体环指蛋白细胞自噬细胞膜受体药物及化合物泛素干扰素G蛋白信号细胞膜蛋白Alzheimers表观遗传学细胞外基质合成与降解

标记一抗

标记类型
HRPBiotinGoldRBITCAPFITCCy3Cy5Cy5.5Cy7PEPE-Cy3PE-Cy5PE-Cy5.5PE-Cy7APCAlexa Fluor 350Alexa Fluor 488Alexa Fluor 555Alexa Fluor 594Alexa Fluor 647

二抗

克隆类型
多抗单抗
产品分类
二抗二抗血清

标记二抗

标记类型
HRPBiotinGoldRBITCAPFITCCy3Cy5Cy5.5Cy7PEPE-Cy3PE-Cy5PE-Cy5.5PE-Cy7APCAlexa Fluor 350Alexa Fluor 488Alexa Fluor 555Alexa Fluor 594Alexa Fluor 647

蛋白质与多肽

产品分类
蛋白质多肽

标记蛋白质与多肽

所有产品
全部标记蛋白质与多肽

正常动物血清及免疫球蛋白

产品分类
正常动物血清免疫球蛋白

试剂盒

产品分类
ELISA试剂盒

常用试剂

产品分类
免疫组化常用试剂免疫印迹常用试剂常用显色试剂细胞生物学试剂分子生物学生化试剂

亲和层析柱

所有产品
亲和层析柱

配套试剂

所有产品
常用配套试剂

ELISA试剂盒

人ELISA试剂盒 大鼠ELISA试剂盒 小鼠ELISA试剂盒 牛ELISA试剂盒 鸡ELISA试剂盒 植物ELISA试剂盒 猴ELISA试剂盒 猪ELISA试剂盒 山羊ELISA试剂盒 马ELISA试剂盒 仓鼠ELISA试剂盒 绵羊ELISA试剂盒 兔子ELISA试剂盒 犬ELISA试剂盒 豚鼠ELISA试剂盒 其他ELISA试剂盒

生化试剂

色素类 分离材料及耗材 维生素 染色剂 碳水化合物 植物激素及核酸 抗生素 蛋白质 氨基酸 测试盒 其他生物试剂 缓冲剂 表面活性剂

血浆

血浆

血清

Sigma胎牛血清 gibco胎牛血清 Hyclone血清 人血清 国产新生牛血清 国产胎牛血清 其他血清

细胞

其它细胞 仓鼠细胞 猴细胞 大鼠细胞 人细胞 狗细胞 小鼠细胞 猫细胞 鸡细胞

标准品

对照品 农药标准品 标准物质 食品 无机溶液标准物质 有机溶液标准物质

抗体

兔抗 鼠抗 IgY抗体 IgA抗体 IgG抗体 二抗 一抗

裂解血

裂解血

培养基

美国药典培养基 化妆品检验培养基 大肠杆菌、大肠菌群 金黄色葡萄球菌检验 消毒灭菌效果评价 临床检验用培养基 中华人民共和国药典 欧洲药典(EP) 饮用天然矿泉水检验方法 微生物检验 霉菌、酵母菌 肠球菌、链球菌 沙门氏菌、志贺氏菌 弧菌 弯曲杆菌 李斯特氏菌 产气荚膜梭菌 阪崎肠杆菌 乳酸菌、双歧杆菌 小肠结肠炎耶尔森氏菌 蜡样芽孢杆菌检验 小肠结肠炎耶尔森氏菌检验 一次性试管、液体培养基 乳酸菌检验 菌落总数测定、无菌检验 显色培养基 植物组培

产品中心

当前位置:首页>产品中心

RABBIT ANTI MOUSE COLLAGEN IV

货号: 2150-1470 基本售价: 3899.0 元 规格: 0.1 ml

产品信息

概述
货号2150-1470
同种亚型Polyclonal IgG
反应种属Mouse
来源宿主Rabbit
应用E, IF, P
性能
供应商Bio-Rad Antibodies
运输条件
存放说明Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
声明
本官网所有报价均为常温或者蓝冰运输价格,如有产品需要干冰运输,需另外加收干冰运输费。
参考图片
Published customer image:
Rabbit anti Mouse collagen 4 antibody (2150-1470) used for the evaluation of pericytes in wild type and Ang2-GOF mice by immunofluorescence.
Image caption:
Immunohistochemistry analysis of pericytes in Ang-2 GOF mice. a Pericytes (desmin+) were decreased in GOF mice utilizing 10 μm cryosections for analysis (n = 8, scale bars 25 μm). b 50 μm vibratome sections of Ang-2 GOF and WT mice revealed decrease in pericyte area/vessel area [%] (n = 3, scale bars 10 μm) indicating decreased pericyte coverage of the vessels in GOF mice

From: Gurnik S, Devraj K, Macas J, Yamaji M, Starke J, Scholz A, Sommer K, Di Tacchio M, Vutukuri R, Beck H, Mittelbronn M, Foerch C, Pfeilschifter W, Liebner S, Peters KG, Plate KH, Reiss Y.
Angiopoietin-2-induced blood-brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling.
Acta Neuropathol. 2016 May;131(5):753-73.
Published customer image:
Rabbit anti Mouse collagen 4 antibody (2150-1470) used for detectiuon of collagen 4 in rat retina by immunofluorescence on cryostat sections.
Image caption
:Retinal gliosis and subretinal neovascularization in RCS rats. Double label immunostaining was performed using antibodies against vimentin (red) and collagen type IV (green) on frozen sections. (A) Non-dystrophic rat at 21 weeks (w) of age showed a normal distribution of retinal vessels confined to the inner retina and absence of glial cells in the subretinal space. (B, C) RCS rats at 6 w (B) and 9 w (C) of age showed activation of Muller cells but without subretinal neovascularization. Muller cell invasion into the subretinal space was more obvious at 9 w compared with 6 w of age (arrows in C). (D) Subretinal neovascularization (arrows) in RCS rats at 13 w of age. GCL = ganglion cell layer, INL = inner nuclear layer, OPL = outer plexiform layer, ONL = outer nuclear layer, SP = subretinal space, CC = choroidal capillaries. Scale bars: 50 µm.

From: Shen W, Chung SH, Irhimeh MR, Li S, Lee S-R, et al. (2014)
Systemic Administration of Erythropoietin Inhibits Retinopathy in RCS Rats.
PLoS ONE 9(8): e104759.
Published customer image:Rabbit anti Mouse collagen 4 antibody (2150-1470) used for the detection of collogen 4 expression in Elk3 knockout mice by immunofluorescence.
Image caption:
Smooth muscle actin and CollagenIV levels are not altered in Elk3(-/-) knockout retinae. (A) IsolectinB4 (ILB4) (left) and smooth muscle actin (SMA) (middle and right) staining of retinal flat-mounts of control (upper panel) and Elk3(-/-) knockout animals. (B) IsolectinB4 (left) and collagenIV (middle and right) staining of retinal flat-mounts of control (upper panel) and Elk3(-/-) knockout animals. (C) Quantitation of collagenIV RNA levels in control and Elk3(-/-) knockout retinae (n = 5 independent experiments). (D) Representative pairs of control and Elk3(-/-) knockout retinal lysates tested for smooth muscle actin expression in Western Blot analysis. (E) Quantitation of control and Elk3(-/-) knockout retinal levels of SMA (n = 5 independent experiments). Scale bar in (A, B left and middle) 1000 μm, in (A, B right) 100 μm.

From: Weinl C, Wasylyk C, Garcia Garrido M, Sothilingam V, Beck SC, et al. (2014)
Elk3 Deficiency Causes Transient Impairment in Post-Natal Retinal Vascular Development and Formation of Tortuous Arteries in Adult Murine Retinae.
PLoS ONE 9(9): e107048.
Published customer image:Rabbit anti Mouse collagen IV antibody (2150-1470) used for the evaluation of collagen IV expression in murine pupillary membranes by immunofluorescence on cryosections.
Image caption:
Vhltrp1-creKO mice demonstrate a Hif1a-dependent persistence of the pupillary membrane. (A-I) Autofluorescence scanning laser ophthalmoscope (AF-SLO) imaging (A,D,G), indocyanin-green angiography (ICGA; B,E,H) and collagen IV-stained cryosections (C,F,I) of Vhltrp1-creKO, Vhl;Hif1atrp1-creKO and control littermates at P21 show a persistent pupillary membrane in Vhltrp1-creKO mice that is absent in Vhl;Hif1atrp1-creKO and control mice. CB, ciliary body. Scale bar: 75 μm.

From: Lange CA, Luhmann UF, Mowat FM, Georgiadis A, West EL, Abrahams S, Sayed H, Powner MB, Fruttiger M, Smith AJ, Sowden JC, Maxwell PH, Ali RR, Bainbridge JW.
Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development.
Development. 2012 Jul;139(13):2340-50.
Published customer image:
Rabbit anti Mouse collagen IV antibody used for the evaluation of collagen IV expression in retinal flat-mountsby immunofluorescence.
Image caption:
Vhltrp1-creKO mice show a persistence of the hyaloid vasculature and a disorganised retinal vasculature that is independent of Hif1a. (A,B,F,G,K,L) Indocyanin-green angiography (A,F,K) and corresponding collagen 4-stained retinal flatmounts (B,G,L) show a persistent hyaloid vasculature in Vhltrp1-creKO and Vhl;Hif1atrp1-creKO mice that is absent in control littermates at P21. Inset in K shows angiography focussed on the persistent hyaloid vasculature. Inset in L shows a light microscopy image of a retinal flat mount with haemorrhage. (C,H,M) Vhltrp1-creKO and Vhl;Hif1atrp1-creKO mice demonstrate a disorganised retinal vasculature with areas of intra-retinal vascular proliferation compared with age-matched controls (hyaloid vessels were removed). Outlined regions indicate the areas selected for IMARES imaging. (D,E,I,J,N,O) IMARES reconstruction reveals a disorganised retinal vasculature with abrogated vascular layering and retinal vessels growing into the outer retina in Vhltrp1-creKO and Vhl;Hif1atrp1-creKO mice. Scale bars: 1 mm for B; 500 μm for C,M; 700 μm for H; 50 μm for D,E,I,J,N,O.

From: Lange CA, Luhmann UF, Mowat FM, Georgiadis A, West EL, Abrahams S, Sayed H, Powner MB, Fruttiger M, Smith AJ, Sowden JC, Maxwell PH, Ali RR, Bainbridge JW.
Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development.
Development. 2012 Jul;139(13):2340-50.
Published customer image:
Rabbit anti Mouse collagen IV antibody (2150-1470) used for the detection of collagen IV in mouse retina by immunofluorescence.
Deletion of Vhl in the RPE results in disruption of the retinal vascular architecture and formation of chorioretinal anastomoses. (A-L) Representative collagen IV-stained cryosections of control (A-D), Vhltrp1-creKO mice (E-H) and Vhl;Hif1atrp1-creKO (I-L) and at different time points during development show a disorganised retinal vasculature and the formation of chorioretinal anastomoses in Vhl;Hif1atrp1-creKO and Vhltrp1-creKO mice (G,K). GCL, ganglion cell layer; NBL, neuroblast layer; Cho, choroid; INL, inner nuclear layer, ONL, outer nuclear layer. Scale bars: 25 μm.

From: Lange CA, Luhmann UF, Mowat FM, Georgiadis A, West EL, Abrahams S, Sayed H, Powner MB, Fruttiger M, Smith AJ, Sowden JC, Maxwell PH, Ali RR, Bainbridge JW. Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development. Development. 2012 Jul;139(13):2340-50.
Published customer image:
Rabbit anti Mouse collagen IV antibody used to visualize collagen IV expression in murine retina by immunofluorecence.
Image caption:
Overexpression of ATX causes abnormal vessel morphology and vessel regression. (A and B) Magnification view of angiogenic front in retina from ATX cTg mice at P6. Control and ATX cTg retinas had similar filopodia protrusion. Scale bar, 50 µm. TM, tamoxifen. (C and D) ATX cTg retinas displayed vessel regression at vascular plexus. Control (wild type) and ATX cTg retinas labeled for CD31 (green) and collagen IV (red). Arrows highlight empty collagen IV sleeves, indicating vessel regression. Scale bar, 100 µm. (E and F) Vessel regression was evaluated quantitatively. Error bars indicate s.d. (control; n = 7, ATX cTg; n = 5). P-values were estimated by student’s t-test, ***P < 0.001. Data were pooled from three independent experiments.

From: Yukiura H, Kano K, Kise R, Inoue A, Aoki J (2015)
Autotaxin Overexpression Causes Embryonic Lethality and Vascular Defects.Citation: Yukiura H, Kano K, Kise R, Inoue A, Aoki J (2015) Autotaxin Overexpression Causes Embryonic Lethality and Vascular Defects.
PLoS ONE 10(5): e0126734.
Published customer image:
Rabbit anti Mouse collagen IV antibody (2150-1470) used for the detection of collagen IV in Murine choroidal flatmounts by immunofluorescence on paraformaldehyde fixed sections.
Image caption:
Choroidal neovascularisation in CCL2-/-CX3CR1GFP/GFP DKO mice. (A) CNV was induced in adult (8~12-week) WT and CCL2-/-CX3CR1GFP/GFP mice. RPE/choroidal flatmounts were collected at day 10 and stained for isolectin B4 (green) and collagen IV (red) and examined by confocal microscopy. (B) CNV size in WT and CCL2-/-CX3CR1GFP/GFP mice at day 10. N?=?6. (C, D) VEGF-A mRNA expression in RPE cells (C) and BM-DMs (D) from WT and CCL2-/-CX3CR1GFP/GFP mice. N?=?5.

From: Chen M, Hombrebueno JR, Luo C, Penalva R, Zhao J, Colhoun L, et al. (2013)
Age- and Light-Dependent Development of Localised Retinal Atrophy in CCL2-/-CX3CR1GFP/GFP Mice.
PLoS ONE 8(4): e61381.