Human/Bovine/Mouse Insulin Allophycocyanin MAb (Cl 182410) (100 TESTS)【科瑞奥博】

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Human/Bovine/Mouse Insulin Allophycocyanin MAb (Cl 182410) (100 TESTS)

货号： IC1417A 基本售价： 5512.4 元规格： 100 Tests

产品信息

概述
货号	IC1417A
别名	IDDM2; ILPR; INS; insulin; IRDN; MODY10; proinsulin
反应种属	Human/Bovine/Mouse
应用	Intracellular Staining by Flow Cytometry
目标/特异性	Detects bovine, human, and mouse insulin.
使用方法	Intracellular Staining by Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3630 (Human); 16333 (Mouse); 397415 (Porcine); 280829 (Bovine); 483665 (Canine)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Pancreatic islet cell phenotype and endocrine function throughout diabetes development in non-obese diabetic mice. Authors: Kornete, Mara, Beauchemin, Hugues, Polychronakos, Constant, Piccirillo, Ciriaco Autoimmunity, 2013;46(4):259-68. Species: Mouse Sample Type: Whole Cells Application: Flow Beta-cell specific deletion of Dicer1 leads to defective insulin secretion and diabetes mellitus. Authors: Kalis M, Bolmeson C, Esguerra JL, Gupta S, Edlund A, Tormo-Badia N, Speidel D, Holmberg D, Mayans S, Khoo NK, Wendt A, Eliasson L, Cilio CM PLoS ONE, 2011;6(12):e29166. Species: Mouse Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	E. coli-derived recombinant human Insulin
生物活性	Human, Mouse, Bovine
标记	Allophycocyanin
背景	Insulin is a disulfide-linked heterodimeric protein secreted by the pancreatic Islets of Langerhans. Mature insulin is generated by the proteolytic removal of a peptide from proinsulin. It is involved in the regulation of glucose metabolism through interactions with the Insulin Receptor.
运输条件	Blue Ice
存放说明	4℃
参考文献	Cytokines in Lipid/Cholesterol Metabolism Diabetes Glucose Homeostasis Growth Hormone/IGF-I Axis ICC / IHC Images: Insulin IGF Family Interactive Pathway: Adipocytokines & Insulin Signaling Metabolism Nutrition and Appetite Pancreatic Endoderm Pancreatic Endoderm Cell Markers Preeclampsia Protein/Peptide Hormones and Regulators

参考图片

Detection of Insulin in beta TC‑6 Mouse Cell Line by Flow Cytometry. beta TC‑6 mouse beta cell insulinoma cell line was stained with Rat Anti-Human/Mouse/Bovine Insulin APC‑conjugated Monoclonal Antibody (Catalog # IC1417A, filled histogram) or isotype control antibody (Catalog # IC006A, open histogram). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules.