货号 | IC1834R-100UG |
别名 | IL-27 p28 subunit; IL-27 subunit alpha; IL27; IL-27; IL27A; IL-27-A; IL27-A; IL27p28; IL30; interleukin 27; interleukin 30; interleukin-27 subunit alpha; MGC71873; p28IL-27A | 全称 | Interleukin 27 |
应用 | Intracellular Staining by Flow Cytometry |
目标/特异性 | Detects mouse IL-27 in Western blots. This antibody recognizes the p28 subunit either as part of a p28/EBI-3 heterodimer or as a free subunit. |
使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 246778 (Human); 246779 (Mouse) |
免疫原 | Chinese hamster ovary cell line CHO-derived recombinant mouse IL‑27 Tyr19-Pro228 (EBI3) & Phe29-Ser234 (p28) Accession # O35228 (EBI3) & Q8K3I6 (p28) |
生物活性 | Mouse |
标记 | Alexa Fluor 647 |
背景 | Interleukin 27 (IL-27) is a novel heterodimeric cytokine comprised of the IL-12 p35-related protein, p28, and the IL-12 p40-related protein, EBI-3 (Epstein‑Barr virus‑induced gene 3). IL-27 binds TCCR/WSX-1 on naïve CD4+ T cells and induces the expression of a functional IL-12 receptor, making these cells sensitive to IL‑12‑mediated Th1 cell development. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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