| 货号 | FAB4504R-100UG |
| 别名 | AI463180; Chandra; Ly116; MS4A4B | 全称 | Membrane-spanning 4-domains, Subfamily A, Member 4B |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects mouse MS4A4B. Stains mouse MS4A4B transfectants but not irrelevant transfectants. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 60361 (Mouse) |
| 免疫原 | HEK293 human embryonic kidney cell line transfected with mouse MS4A4B Met1-Val226 Accession # NP_068364 |
| 生物活性 | Mouse |
| 标记 | Alexa Fluor 647 |
| 背景 | MS4A4B, also called Chandra, is a member of the MS4A family of four-transmembrane proteins that includes CD20. It is expressed in immature CD4-CD8- T cells, and later in mature Th1 but not Th2 cells. MS4A4B is enriched in lipid rafts of activated T cells, and overexpression enhances Th1 cytokine expression, indicating a possible role in cell signaling. Mouse MS4A4B shares 69% overall amino acid (aa) identity with rat, and low (< 40%) aa identity with human MS4A4B. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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