| 货号 | FAB33281T-100UG |
| 别名 | CD223 antigen; CD223; FDC; LAG3; LAG-3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Protein FDC | 全称 | Lymphocyte-activation Gene 3 |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects mouse LAG-3 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinanthuman LAG-3 is observed. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3902 (Human); 16768 (Mouse); 297596 (Rat); 102122272 (Cynomolgus Monkey) |
| 免疫原 | NS0 mouse myeloma cell line transfected with mouse LAG-3 Ser23-Leu442 Accession # Q61790 |
| 生物活性 | Mouse |
| 标记 | Alexa Fluor 594 |
| 背景 | LAG-3 (Lymphocyte activation gene-3; CD223 in the human) is a member of the immunoglobulin superfamily (IgSF). The mature LAG-3 protein is a 496 amino acid (aa) membrane protein with a 421 aa extracellular region which contains four IgSF domains, a 21 aa transmembrane region and a 54 aa cytoplasmic region. LAG-3 shares < 20% amino acid sequence homology with CD4, but has similar structure and binds to MHC class II with higher affinity. The mouse LAG-3 extracellular region shares 69% aa sequence identity with human LAG-3. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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