货号 | IC1935G-100UG |
别名 | ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; BHLHE78; Class E basic helix-loop-helix protein 78; HIF 1A; HIF1 alpha; HIF-1 alpha; HIF1A; HIF-1a; HIF-1-alpha; HIF1-alpha; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcriptionfactor); hypoxia-inducible factor 1-alpha; Member of PAS protein 1; member of PAS superfamily 1; MOP1HIF1-ALPHA; PAS domain-containing protein 8; PASD8alpha subunit (basic helix-loop-helix transcriptionfactor) | 全称 | Hypoxia-inducible Transcription Factor 1 alpha |
应用 | Intracellular Staining by Flow Cytometry |
目标/特异性 | Recognizes human and mouse HIF-1 alpha in direct ELISAs. |
使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 3091 (Human); 15251 (Mouse); 29560 (Rat) |
免疫原 | E. coli-derived recombinant human HIF-1 alpha Arg575-Asn826 Accession # Q16665.1 |
生物活性 | Human, Mouse |
标记 | Alexa Fluor 488 |
背景 | The hypoxia-inducible transcription factor 1 alpha (HIF-1 alpha ) is the regulated member of the transcription factor heterodimer HIF-1. HIF-1 binds to hypoxia-response elements (HREs) in the promoters of many genes involved in adapting to an environment of insufficient oxygen or hypoxia. Hypoxic tissue environments occur in vascular and pulmonary diseases as well as cancer, which illustrates the broad impact of gene regulation by HIF-1 alpha. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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